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Regulation of basal cellular physiology by the homeostatic unfolded protein response

The Journal of cell biology, 2010-05, Vol.189 (5), p.783-794

2010

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Experimental reconstitution of chronic ER stress in the liver reveals feedback suppression of BiP mRNA expression

eLife, 2016-12, Vol.5

2016

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Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins

PLoS biology, 2006-11, Vol.4 (11), p.e374

2006

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Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response

Cell, 2006-02, Vol.124 (3), p.587-599

2006

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The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis

PLoS genetics, 2013-12, Vol.9 (12), p.e1003937

2013

Volltextzugriff (PDF)

Influenza A Viral Replication Is Blocked by Inhibition of the Inositol-requiring Enzyme 1 (IRE1) Stress Pathway

The Journal of biological chemistry, 2012-02, Vol.287 (7), p.4679-4689

2012

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Liver function and dysfunction – a unique window into the physiological reach of ER stress and the unfolded protein response

The FEBS journal, 2019-01, Vol.286 (2), p.356-378

Rutkowski, D. Thomas

2019

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UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

Developmental cell, 2008-12, Vol.15 (6), p.829-840

2008

Volltextzugriff (PDF)

Endoplasmic reticulum stress impairs IL-4/IL-13 signaling through C/EBPβ-mediated transcriptional suppression

Journal of cell science, 2013-09, Vol.126 (Pt 17), p.4026-4036

2013

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A data-entrained computational model for testing the regulatory logic of the vertebrate unfolded protein response

Molecular biology of the cell, 2018-06, Vol.29 (12), p.1502-1517

2018

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ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis

Cell reports (Cambridge), 2017-05, Vol.19 (9), p.1794-1806

2017

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NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis

iScience, 2020-05, Vol.23 (5), p.101116-101116, Article 101116

2020

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Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences

Frontiers in genetics, 2013-12, Vol.4, p.256-256

2013

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Pathways Linking Nicotinamide Adenine Dinucleotide Phosphate Production to Endoplasmic Reticulum Protein Oxidation and Stress

Frontiers in molecular biosciences, 2022-05, Vol.9, p.858142-858142

2022

Volltextzugriff (PDF)

Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (5), p.1392-1397

2009

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Interference with the HNF4-dependent gene regulatory network diminishes endoplasmic reticulum stress in hepatocytes

Hepatology communications, 2023-11, Vol.7 (11)

2023

Volltextzugriff (PDF)

Compliance and Dead Space Fraction Indicate an Optimal Level of Positive End-Expiratory Pressure After Recruitment in Anesthetized Patients

Anesthesia and analgesia, 2008, Vol.106 (1), p.175-181

2008

Volltextzugriff (PDF)

That which does not kill me makes me stronger: adapting to chronic ER stress

Trends in biochemical sciences (Amsterdam. Regular ed.), 2007-10, Vol.32 (10), p.469-476

2007

Volltextzugriff (PDF)

A beneficial adaptive role for CHOP in driving cell fate selection during ER stress

EMBO reports, 2024-01, Vol.25 (1), p.228-253

2024

Volltextzugriff (PDF)

Temporal clustering of gene expression links the metabolic transcription factor HNF4α to the ER stress-dependent gene regulatory network

Frontiers in genetics, 2013, Vol.4, p.188-188

2013

Volltextzugriff (PDF)

A trip to the ER: coping with stress

Trends in cell biology, 2004, Vol.14 (1), p.20-28

2004

Volltextzugriff (PDF)

Heightened Induction of Proapoptotic Signals in Response to Endoplasmic Reticulum Stress in Primary Fibroblasts from a Mouse Model of Longevity

The Journal of biological chemistry, 2011-09, Vol.286 (35), p.30344-30351

2011

Volltextzugriff (PDF)

ATF6α Optimizes Long-Term Endoplasmic Reticulum Function to Protect Cells from Chronic Stress

Developmental cell, 2007-09, Vol.13 (3), p.351-364

2007

Volltextzugriff (PDF)

The Unfolded Protein Response Mediates Adaptation to Exercise in Skeletal Muscle through a PGC-1α/ATF6α Complex

Cell metabolism, 2011-02, Vol.13 (2), p.160-169

2011

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Signal Sequences Initiate the Pathway of Maturation in the Endoplasmic Reticulum Lumen

The Journal of biological chemistry, 2003-08, Vol.278 (32), p.30365-30372

2003

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Regulation of basal cellular physiology by the homeostatic unfolded protein response

Experimental reconstitution of chronic ER stress in the liver reveals feedback suppression of BiP mRNA expression

Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins

Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response

The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis

Influenza A Viral Replication Is Blocked by Inhibition of the Inositol-requiring Enzyme 1 (IRE1) Stress Pathway

Liver function and dysfunction – a unique window into the physiological reach of ER stress and the unfolded protein response

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

Endoplasmic reticulum stress impairs IL-4/IL-13 signaling through C/EBPβ-mediated transcriptional suppression

A data-entrained computational model for testing the regulatory logic of the vertebrate unfolded protein response

ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis

NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis

Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences

Pathways Linking Nicotinamide Adenine Dinucleotide Phosphate Production to Endoplasmic Reticulum Protein Oxidation and Stress

Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS

Interference with the HNF4-dependent gene regulatory network diminishes endoplasmic reticulum stress in hepatocytes

Compliance and Dead Space Fraction Indicate an Optimal Level of Positive End-Expiratory Pressure After Recruitment in Anesthetized Patients

That which does not kill me makes me stronger: adapting to chronic ER stress

A beneficial adaptive role for CHOP in driving cell fate selection during ER stress

Temporal clustering of gene expression links the metabolic transcription factor HNF4α to the ER stress-dependent gene regulatory network

A trip to the ER: coping with stress

Heightened Induction of Proapoptotic Signals in Response to Endoplasmic Reticulum Stress in Primary Fibroblasts from a Mouse Model of Longevity

ATF6α Optimizes Long-Term Endoplasmic Reticulum Function to Protect Cells from Chronic Stress

The Unfolded Protein Response Mediates Adaptation to Exercise in Skeletal Muscle through a PGC-1α/ATF6α Complex

Signal Sequences Initiate the Pathway of Maturation in the Endoplasmic Reticulum Lumen

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