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Druggable Biomarkers Altered in Clear Cell Renal Cell Carcinoma: Strategy for the Development of Mechanism-Based Combination Therapy

International journal of molecular sciences, 2023-01, Vol.24 (2), p.902

2023

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Potential Role of Selenium in the Treatment of Cancer and Viral Infections

International journal of molecular sciences, 2022-02, Vol.23 (4), p.2215

2022

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A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity

PloS one, 2012-09, Vol.7 (9), p.e45571

2012

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MicroRNA-627 Mediates the Epigenetic Mechanisms of Vitamin D to Suppress Proliferation of Human Colorectal Cancer Cells and Growth of Xenograft Tumors in Mice

Gastroenterology (New York, N.Y. 1943), 2013-08, Vol.145 (2), p.437-446

2013

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Non-Coding Micro RNAs and Hypoxia-Inducible Factors Are Selenium Targets for Development of a Mechanism-Based Combination Strategy in Clear-Cell Renal Cell Carcinoma-Bench-to-Bedside Therapy

International journal of molecular sciences, 2018-10, Vol.19 (11), p.3378

2018

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MicroRNA Expression in Clear Cell Renal Cell Carcinoma Cell Lines and Tumor Biopsies: Potential Therapeutic Targets

International journal of molecular sciences, 2022-05, Vol.23 (10), p.5604

2022

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Selective Modulation of the Therapeutic Efficacy of Anticancer Drugs by Selenium Containing Compounds against Human Tumor Xenografts

Clinical cancer research, 2004-04, Vol.10 (7), p.2561-2569

2004

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Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases

Rustum, Youcef M

2019

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Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition

BMC cancer, 2012-07, Vol.12 (1), p.293-293, Article 293

2012

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Irinotecan in the Treatment of Colorectal Cancer: Clinical Overview

Journal of clinical oncology, 2001-03, Vol.19 (5), p.1501-1518

2001

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Selenium targets resistance biomarkers enhancing efficacy while reducing toxicity of anti-cancer drugs: preclinical and clinical development

Oncotarget, 2018-02, Vol.9 (12), p.10765-10783

2018

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Bevacizumab enhances the therapeutic efficacy of Irinotecan against human head and neck squamous cell carcinoma xenografts

Oral oncology, 2011-06, Vol.47 (6), p.459-466

2011

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Tumor Vascular Maturation and Improved Drug Delivery Induced by Methylselenocysteine Leads to Therapeutic Synergy with Anticancer Drugs

Clinical cancer research, 2008-06, Vol.14 (12), p.3926-3932

2008

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Thymidylate synthase: a critical target in cancer therapy?

Frontiers in bioscience, 2004-09, Vol.9 (1-3), p.2467

Rustum, Youcef M

2004

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A Phase I, Pharmacokinetic and Pharmacodynamic Study on Vorinostat in Combination with 5-Fluorouracil, Leucovorin, and Oxaliplatin in Patients with Refractory Colorectal Cancer

Clinical cancer research, 2009-05, Vol.15 (9), p.3189-3195

2009

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Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers

Molecular cancer, 2010-12, Vol.9 (1), p.310-310, Article 310

2010

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Enrico Mihich, MD: In Memoriam (1928-2016)

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13), p.3383-3385

2017

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Methylseleninic Acid Potentiates Apoptosis Induced by Chemotherapeutic Drugs in Androgen-Independent Prostate Cancer Cells

Clinical cancer research, 2005-03, Vol.11 (6), p.2379-2388

2005

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Cellular Topoisomerase I Inhibition and Antiproliferative Activity by MJ-III-65 (NSC 706744), an Indenoisoquinoline Topoisomerase I Poison

Molecular pharmacology, 2005-02, Vol.67 (2), p.523-530

2005

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Therapeutic Synergy Between Irinotecan and 5-Fluorouracil against Human Tumor Xenografts

Clinical cancer research, 2004-02, Vol.10 (3), p.1121-1129

2004

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Phase II Study of Weekly Intravenous Oxaliplatin Combined With Oral Daily Capecitabine and Radiotherapy With Biologic Correlates in Neoadjuvant Treatment of Rectal Adenocarcinoma

International journal of radiation oncology, biology, physics, 2008-11, Vol.72 (3), p.650-657

2008

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Activity of the Vascular-Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid against Human Head and Neck Carcinoma Xenografts

Neoplasia (New York, N.Y.), 2006-07, Vol.8 (7), p.534-542

2006

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Celecoxib and Mucosal Protection: Translation from an Animal Model to a Phase I Clinical Trial of Celecoxib, Irinotecan, and 5-Fluorouracil

Clinical cancer research, 2007-02, Vol.13 (3), p.965-971

2007

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A phase I and pharmacokinetic study of fixed-dose selenomethionine and irinotecan in solid tumors

Clinical cancer research, 2006-02, Vol.12 (4), p.1237-1244

2006

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The mechanism of methylselenocysteine and docetaxel synergistic activity in prostate cancer cells

Molecular cancer therapeutics, 2006-10, Vol.5 (10), p.2540-2548

2006

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Druggable Biomarkers Altered in Clear Cell Renal Cell Carcinoma: Strategy for the Development of Mechanism-Based Combination Therapy

Potential Role of Selenium in the Treatment of Cancer and Viral Infections

A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity

MicroRNA-627 Mediates the Epigenetic Mechanisms of Vitamin D to Suppress Proliferation of Human Colorectal Cancer Cells and Growth of Xenograft Tumors in Mice

Non-Coding Micro RNAs and Hypoxia-Inducible Factors Are Selenium Targets for Development of a Mechanism-Based Combination Strategy in Clear-Cell Renal Cell Carcinoma-Bench-to-Bedside Therapy

MicroRNA Expression in Clear Cell Renal Cell Carcinoma Cell Lines and Tumor Biopsies: Potential Therapeutic Targets

Selective Modulation of the Therapeutic Efficacy of Anticancer Drugs by Selenium Containing Compounds against Human Tumor Xenografts

Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases

Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition

Irinotecan in the Treatment of Colorectal Cancer: Clinical Overview

Selenium targets resistance biomarkers enhancing efficacy while reducing toxicity of anti-cancer drugs: preclinical and clinical development

Bevacizumab enhances the therapeutic efficacy of Irinotecan against human head and neck squamous cell carcinoma xenografts

Tumor Vascular Maturation and Improved Drug Delivery Induced by Methylselenocysteine Leads to Therapeutic Synergy with Anticancer Drugs

Thymidylate synthase: a critical target in cancer therapy?

A Phase I, Pharmacokinetic and Pharmacodynamic Study on Vorinostat in Combination with 5-Fluorouracil, Leucovorin, and Oxaliplatin in Patients with Refractory Colorectal Cancer

Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers

Enrico Mihich, MD: In Memoriam (1928-2016)

Methylseleninic Acid Potentiates Apoptosis Induced by Chemotherapeutic Drugs in Androgen-Independent Prostate Cancer Cells

Cellular Topoisomerase I Inhibition and Antiproliferative Activity by MJ-III-65 (NSC 706744), an Indenoisoquinoline Topoisomerase I Poison

Therapeutic Synergy Between Irinotecan and 5-Fluorouracil against Human Tumor Xenografts

Phase II Study of Weekly Intravenous Oxaliplatin Combined With Oral Daily Capecitabine and Radiotherapy With Biologic Correlates in Neoadjuvant Treatment of Rectal Adenocarcinoma

Activity of the Vascular-Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid against Human Head and Neck Carcinoma Xenografts

Celecoxib and Mucosal Protection: Translation from an Animal Model to a Phase I Clinical Trial of Celecoxib, Irinotecan, and 5-Fluorouracil

A phase I and pharmacokinetic study of fixed-dose selenomethionine and irinotecan in solid tumors

The mechanism of methylselenocysteine and docetaxel synergistic activity in prostate cancer cells

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