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Host-directed therapies for infectious diseases: current status, recent progress, and future prospects

The Lancet infectious diseases, 2016-04, Vol.16 (4), p.e47-e63

2016

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A Four-Month Gatifloxacin-Containing Regimen for Treating Tuberculosis

The New England journal of medicine, 2014-10, Vol.371 (17), p.1588-1598

2014

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Tuberculosis—advances in development of new drugs, treatment regimens, host-directed therapies, and biomarkers

The Lancet infectious diseases, 2016-04, Vol.16 (4), p.e34-e46

2016

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Rapid Molecular Detection of Tuberculosis and Rifampin Resistance

The New England journal of medicine, 2010-09, Vol.363 (11), p.1005-1015

2010

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The Diarylquinoline TMC207 for Multidrug-Resistant Tuberculosis

The New England journal of medicine, 2009-06, Vol.360 (23), p.2397-2405

2009

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Reduced Antituberculosis Drug Concentrations in HIV-Infected Patients Who Are Men or Have Low Weight: Implications for International Dosing Guidelines

Antimicrobial Agents and Chemotherapy, 2012-06, Vol.56 (6), p.3232-3238

2012

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Effect of standard tuberculosis treatment on plasma cytokine levels in patients with active pulmonary tuberculosis

PloS one, 2012-05, Vol.7 (5), p.e36886

2012

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High rates of potentially infectious tuberculosis and multidrug-resistant tuberculosis (MDR-TB) among hospital inpatients in KwaZulu Natal, South Africa indicate risk of nosocomial transmission

PloS one, 2014-03, Vol.9 (3), p.e90868-e90868

2014

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Early versus delayed initiation of highly active antiretroviral therapy for HIV-positive adults with newly diagnosed pulmonary tuberculosis (TB-HAART): a prospective, international, randomised, placebo-controlled trial

The Lancet infectious diseases, 2014-07, Vol.14 (7), p.563-571

2014

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A Semimechanistic Pharmacokinetic-Enzyme Turnover Model for Rifampin Autoinduction in Adult Tuberculosis Patients

Antimicrobial Agents and Chemotherapy, 2012-04, Vol.56 (4), p.2091-2098

2012

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Vaccine Licensure in the Absence of Human Efficacy Data

Vaccines (Basel), 2022-02, Vol.10 (3), p.368

2022

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Bridging Animal and Human Data in Pursuit of Vaccine Licensure

Vaccines (Basel), 2022-08, Vol.10 (9), p.1384

2022

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Use of a WHO-recommended algorithm to reduce mortality in seriously ill patients with HIV infection and smear-negative pulmonary tuberculosis in South Africa: an observational cohort study

The Lancet infectious diseases, 2011-07, Vol.11 (7), p.533-540

2011

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Incidence and Geographic Distribution of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal Province, South Africa

PloS one, 2015-07, Vol.10 (7), p.e0132076-e0132076

2015

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Evaluation of Initial and Steady-State Gatifloxacin Pharmacokinetics and Dose in Pulmonary Tuberculosis Patients by Using Monte Carlo Simulations

Antimicrobial Agents and Chemotherapy, 2013-09, Vol.57 (9), p.4164-4171

2013

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Middle East Respiratory Syndrome - need for increased vigilance and watchful surveillance for MERS-CoV in sub-Saharan Africa

International journal of infectious diseases, 2015-08, Vol.37 (C), p.77-79

2015

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Impact of tuberculosis treatment and antiretroviral therapy on serial RD-1-specific quantitative T-cell readouts (QuantiFERON-TB Gold In-Tube), and relationship to treatment-related outcomes and bacterial burden

International journal of infectious diseases, 2015-07, Vol.36 (C), p.46-53

2015

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Treatment of tuberculosis: present status and future prospects

Bulletin of the World Health Organization, 2005-11, Vol.83 (11), p.857-865

2005

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The Early Bactericidal Activities of Rifampin and Rifapentine in Pulmonary Tuberculosis

American journal of respiratory and critical care medicine, 2005-07, Vol.172 (1), p.128-135

2005

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What We Know About Tuberculosis Transmission: An Overview

The Journal of infectious diseases, 2017-11, Vol.216 (suppl_6), p.S629-S635

2017

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A pivotal registration phase III, multicenter, randomized tuberculosis controlled trial: design issues and lessons learnt from the Gatifloxacin for TB (OFLOTUB) project

Trials, 2012-05, Vol.13 (1), p.61-61, Article 61

2012

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Drivers of Tuberculosis Transmission

The Journal of infectious diseases, 2017-11, Vol.216 (suppl_6), p.S644-S653

2017

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Model-Based Evaluation of Higher Doses of Rifampin Using a Semimechanistic Model Incorporating Autoinduction and Saturation of Hepatic Extraction

Antimicrobial agents and chemotherapy, 2016-01, Vol.60 (1), p.487-494

2016

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N -Acetyltransferase 2 Genotypes among Zulu-Speaking South Africans and Isoniazid and N -Acetyl-Isoniazid Pharmacokinetics during Antituberculosis Treatment

Antimicrobial agents and chemotherapy, 2020-03, Vol.64 (4)

2020

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Pharmacokinetics of Pyrazinamide and Optimal Dosing Regimens for Drug-Sensitive and -Resistant Tuberculosis

Antimicrobial agents and chemotherapy, 2017-08, Vol.61 (8)

2017

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Host-directed therapies for infectious diseases: current status, recent progress, and future prospects

A Four-Month Gatifloxacin-Containing Regimen for Treating Tuberculosis

Tuberculosis—advances in development of new drugs, treatment regimens, host-directed therapies, and biomarkers

Rapid Molecular Detection of Tuberculosis and Rifampin Resistance

The Diarylquinoline TMC207 for Multidrug-Resistant Tuberculosis

Reduced Antituberculosis Drug Concentrations in HIV-Infected Patients Who Are Men or Have Low Weight: Implications for International Dosing Guidelines

Effect of standard tuberculosis treatment on plasma cytokine levels in patients with active pulmonary tuberculosis

High rates of potentially infectious tuberculosis and multidrug-resistant tuberculosis (MDR-TB) among hospital inpatients in KwaZulu Natal, South Africa indicate risk of nosocomial transmission

Early versus delayed initiation of highly active antiretroviral therapy for HIV-positive adults with newly diagnosed pulmonary tuberculosis (TB-HAART): a prospective, international, randomised, placebo-controlled trial

A Semimechanistic Pharmacokinetic-Enzyme Turnover Model for Rifampin Autoinduction in Adult Tuberculosis Patients

Vaccine Licensure in the Absence of Human Efficacy Data

Bridging Animal and Human Data in Pursuit of Vaccine Licensure

Use of a WHO-recommended algorithm to reduce mortality in seriously ill patients with HIV infection and smear-negative pulmonary tuberculosis in South Africa: an observational cohort study

Incidence and Geographic Distribution of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal Province, South Africa

Evaluation of Initial and Steady-State Gatifloxacin Pharmacokinetics and Dose in Pulmonary Tuberculosis Patients by Using Monte Carlo Simulations

Middle East Respiratory Syndrome - need for increased vigilance and watchful surveillance for MERS-CoV in sub-Saharan Africa

Impact of tuberculosis treatment and antiretroviral therapy on serial RD-1-specific quantitative T-cell readouts (QuantiFERON-TB Gold In-Tube), and relationship to treatment-related outcomes and bacterial burden

Treatment of tuberculosis: present status and future prospects

The Early Bactericidal Activities of Rifampin and Rifapentine in Pulmonary Tuberculosis

What We Know About Tuberculosis Transmission: An Overview

A pivotal registration phase III, multicenter, randomized tuberculosis controlled trial: design issues and lessons learnt from the Gatifloxacin for TB (OFLOTUB) project

Drivers of Tuberculosis Transmission

Model-Based Evaluation of Higher Doses of Rifampin Using a Semimechanistic Model Incorporating Autoinduction and Saturation of Hepatic Extraction

N -Acetyltransferase 2 Genotypes among Zulu-Speaking South Africans and Isoniazid and N -Acetyl-Isoniazid Pharmacokinetics during Antituberculosis Treatment

Pharmacokinetics of Pyrazinamide and Optimal Dosing Regimens for Drug-Sensitive and -Resistant Tuberculosis

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