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Maternal Serotonin Reuptake Inhibitor Antidepressants Have Acute Effects on Fetal Heart Rate Variability in Late Gestation

Frontiers in psychiatry, 2021-08, Vol.12, p.680177-680177

2021

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A validated enantioselective assay for the simultaneous quantitation of ( R)-, ( S)-fluoxetine and ( R)-, ( S)-norfluoxetine in ovine plasma using liquid chromatography with tandem mass spectrometry (LC/MS/MS)

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011-02, Vol.879 (5), p.349-358

2011

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An in vivo evaluation of the ontogeny of stereoselective fluoxetine metabolism and disposition in lambs from birth to one year of age

Xenobiotica, 2019-11, Vol.49 (11), p.1360-1372

2019

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Kinetics of valproic acid glucuronidation: evidence for in vivo autoactivation

Drug metabolism and disposition, 2007-08, Vol.35 (8), p.1380

2007

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Stereoselective pharmacokinetics of fluoxetine and norfluoxetine enantiomers in pregnant sheep

Drug metabolism and disposition, 2004-02, Vol.32 (2), p.212

2004

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A pharmacokinetic study of diphenhydramine transport across the blood-brain barrier in adult sheep: potential involvement of a carrier-mediated mechanism

Drug metabolism and disposition, 2006-06, Vol.34 (6), p.955

2006

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The use of microdialysis for the study of drug kinetics: central nervous system pharmacokinetics of diphenhydramine in fetal, newborn, and adult sheep

Drug metabolism and disposition, 2007-08, Vol.35 (8), p.1285

2007

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Stereoselective disposition of fluoxetine and norfluoxetine during pregnancy and breast‐feeding

British journal of clinical pharmacology, 2006-02, Vol.61 (2), p.155-163

2006

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Chronic fetal and maternal instrumentation in pregnant sheep: effect on gestation length and birthweight

Reproduction fertility and development, 2010, Vol.22 (2), p.459

2010

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Fluoxetine during pregnancy: impact on fetal development

Reproduction fertility and development, 2005-01, Vol.17 (6), p.641

2005

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Chronic maternal fluoxetine infusion in pregnant sheep: Effects on the maternal and fetal hypothalamic-pituitary-adrenal axes

Pediatric research, 2004-07, Vol.56 (1), p.40-46

2004

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Disposition of valproic acid in maternal, fetal, and newborn sheep. I: placental transfer, plasma protein binding, and clearance

Drug metabolism and disposition, 2000-07, Vol.28 (7), p.845

2000

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Role of the liver and gut in systemic diphenhydramine clearance in adult nonpregnant sheep

Drug metabolism and disposition, 1999-02, Vol.27 (2), p.297

1999

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Disposition of valproic acid in maternal, fetal, and newborn sheep. II: metabolism and renal elimination

Drug metabolism and disposition, 2000-07, Vol.28 (7), p.857

2000

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Dose-dependent pharmacokinetics and metabolism of valproic acid in newborn lambs and adult sheep

Drug metabolism and disposition, 2001-05, Vol.29 (5), p.664

2001

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Comparative formation, distribution, and elimination kinetics of diphenylmethoxyacetic acid (a diphenhydramine metabolite) in maternal and fetal sheep

Drug metabolism and disposition, 1999-04, Vol.27 (4), p.463

1999

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Diphenhydramine disposition in the sheep maternal-placental-fetal unit: gestational age, plasma drug protein binding, and umbilical blood flow effects on clearance

Drug metabolism and disposition, 2000-03, Vol.28 (3), p.279

2000

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Clearance and disposition of indometacin in chronically instrumented fetal lambs following a 3-day continuous intravenous infusion

Journal of pharmacy and pharmacology, 2002-06, Vol.54 (6), p.801-808

2002

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Pharmacokinetics and Renal Excretion of Diphenhydramine and its Metabolites, Diphenylmethoxyacetic Acid and Diphenhydramine‐N‐Oxide, in Developing Lambs

Journal of pharmaceutical sciences, 2000-10, Vol.89 (10), p.1362-1370

2000

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Effects of acute moderate hypoxemia on kinetics of metoclopramide and its metabolites in chronically instrumented sheep

Archives of pharmacal research, 2002-10, Vol.25 (5), p.709-717

2002

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Estimation of transplacental and nonplacental diphenhydramine clearances in the fetal lamb: the impact of fetal first-pass hepatic drug uptake

The Journal of pharmacology and experimental therapeutics, 1997-08, Vol.282 (2), p.617

1997

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Use of an automated fluorescent microsphere method to measure regional blood flow in the fetal lamb

Canadian journal of physiology and pharmacology, 1997-08, Vol.75 (8), p.959

1997

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Ontogeny of valproic acid disposition and metabolism: a developmental study in postnatal lambs and adult sheep

Drug metabolism and disposition, 2000-08, Vol.28 (8), p.912

2000

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Maternal Fluoxetine Infusion Does Not Alter Fetal Endocrine and Biophysical Circadian Rhythms in Pregnant Sheep

Journal of the Society for Gynecologic Investigation, 2005-07, Vol.12 (5), p.356-364

2005

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Simultaneous determination of diphenhydramine, its N-oxide metabolite and their deuterium-labeled analogues in ovine plasma and urine using liquid chromatography/electrospray tandem mass spectrometry

Journal of mass spectrometry., 1998-12, Vol.33 (12), p.1171-1181

1998

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Maternal Serotonin Reuptake Inhibitor Antidepressants Have Acute Effects on Fetal Heart Rate Variability in Late Gestation

A validated enantioselective assay for the simultaneous quantitation of ( R)-, ( S)-fluoxetine and ( R)-, ( S)-norfluoxetine in ovine plasma using liquid chromatography with tandem mass spectrometry (LC/MS/MS)

An in vivo evaluation of the ontogeny of stereoselective fluoxetine metabolism and disposition in lambs from birth to one year of age

Kinetics of valproic acid glucuronidation: evidence for in vivo autoactivation

Stereoselective pharmacokinetics of fluoxetine and norfluoxetine enantiomers in pregnant sheep

A pharmacokinetic study of diphenhydramine transport across the blood-brain barrier in adult sheep: potential involvement of a carrier-mediated mechanism

The use of microdialysis for the study of drug kinetics: central nervous system pharmacokinetics of diphenhydramine in fetal, newborn, and adult sheep

Stereoselective disposition of fluoxetine and norfluoxetine during pregnancy and breast‐feeding

Chronic fetal and maternal instrumentation in pregnant sheep: effect on gestation length and birthweight

Fluoxetine during pregnancy: impact on fetal development

Chronic maternal fluoxetine infusion in pregnant sheep: Effects on the maternal and fetal hypothalamic-pituitary-adrenal axes

Disposition of valproic acid in maternal, fetal, and newborn sheep. I: placental transfer, plasma protein binding, and clearance

Role of the liver and gut in systemic diphenhydramine clearance in adult nonpregnant sheep

Disposition of valproic acid in maternal, fetal, and newborn sheep. II: metabolism and renal elimination

Dose-dependent pharmacokinetics and metabolism of valproic acid in newborn lambs and adult sheep

Comparative formation, distribution, and elimination kinetics of diphenylmethoxyacetic acid (a diphenhydramine metabolite) in maternal and fetal sheep

Diphenhydramine disposition in the sheep maternal-placental-fetal unit: gestational age, plasma drug protein binding, and umbilical blood flow effects on clearance

Clearance and disposition of indometacin in chronically instrumented fetal lambs following a 3-day continuous intravenous infusion

Pharmacokinetics and Renal Excretion of Diphenhydramine and its Metabolites, Diphenylmethoxyacetic Acid and Diphenhydramine‐N‐Oxide, in Developing Lambs

Effects of acute moderate hypoxemia on kinetics of metoclopramide and its metabolites in chronically instrumented sheep

Estimation of transplacental and nonplacental diphenhydramine clearances in the fetal lamb: the impact of fetal first-pass hepatic drug uptake

Use of an automated fluorescent microsphere method to measure regional blood flow in the fetal lamb

Ontogeny of valproic acid disposition and metabolism: a developmental study in postnatal lambs and adult sheep

Maternal Fluoxetine Infusion Does Not Alter Fetal Endocrine and Biophysical Circadian Rhythms in Pregnant Sheep

Simultaneous determination of diphenhydramine, its N-oxide metabolite and their deuterium-labeled analogues in ovine plasma and urine using liquid chromatography/electrospray tandem mass spectrometry

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