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Ontogeny of valproic acid disposition and metabolism: a developmental study in postnatal lambs and adult sheep

Drug metabolism and disposition, 2000-08, Vol.28 (8), p.912

2000

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Measurement of rest and activity in newborn lambs using actigraphy: studies in term and preterm lambs

Reproduction fertility and development, 2008-01, Vol.20 (3), p.418

2008

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Disposition of valproic acid in maternal, fetal, and newborn sheep. I: placental transfer, plasma protein binding, and clearance

Drug metabolism and disposition, 2000-07, Vol.28 (7), p.845

2000

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Role of the liver and gut in systemic diphenhydramine clearance in adult nonpregnant sheep

Drug metabolism and disposition, 1999-02, Vol.27 (2), p.297

1999

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Disposition of valproic acid in maternal, fetal, and newborn sheep. II: metabolism and renal elimination

Drug metabolism and disposition, 2000-07, Vol.28 (7), p.857

2000

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Comparative formation, distribution, and elimination kinetics of diphenylmethoxyacetic acid (a diphenhydramine metabolite) in maternal and fetal sheep

Drug metabolism and disposition, 1999-04, Vol.27 (4), p.463

1999

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Simultaneous determination of diphenhydramine, its N-oxide metabolite and their deuterium-labeled analogues in ovine plasma and urine using liquid chromatography/electrospray tandem mass spectrometry

Journal of mass spectrometry., 1998-12, Vol.33 (12), p.1171-1181

1998

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Diphenhydramine disposition in the sheep maternal-placental-fetal unit: gestational age, plasma drug protein binding, and umbilical blood flow effects on clearance

Drug metabolism and disposition, 2000-03, Vol.28 (3), p.279

2000

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Clearance and disposition of indometacin in chronically instrumented fetal lambs following a 3-day continuous intravenous infusion

Journal of pharmacy and pharmacology, 2002-06, Vol.54 (6), p.801-808

2002

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Dose-dependent pharmacokinetics and metabolism of valproic acid in newborn lambs and adult sheep

Drug metabolism and disposition, 2001-05, Vol.29 (5), p.664

2001

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The pharmacokinetics of valproic acid in pregnant sheep after maternal and fetal intravenous bolus administration

Drug metabolism and disposition, 1995-12, Vol.23 (12), p.1383

1995

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Blood volume restitution and growth in fetal lambs after acute hemorrhage

American journal of physiology. Regulatory, integrative and comparative physiology, 1995-10, Vol.269 (4), p.749-R757

1995

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Diphenhydramine disposition in the sheep maternal–Placental–Fetal unit: Determinants of plasma drug concentrations in the mother and the fetus

Journal of pharmaceutical sciences, 1999-12, Vol.88 (12), p.1259-1265

1999

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Oxygen consumption in the fetal lamb during sustained hypoxemia with progressive acidemia

American journal of physiology. Regulatory, integrative and comparative physiology, 1990-05, Vol.258 (5), p.1108-R1115

1990

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Blood flow and oxygen delivery to fetal organs and tissues during sustained hypoxemia

American journal of physiology. Regulatory, integrative and comparative physiology, 1990-05, Vol.258 (5), p.1116-R1122

1990

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Oxygen consumption, acid-base status, and behavior during and after acute, severe hemorrhage in fetal lambs

American journal of physiology. Regulatory, integrative and comparative physiology, 1995-10, Vol.269 (4), p.758-R766

1995

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Hepatic first-pass uptake of diphenhydramine. A comparative study between fetal and adult sheep

Drug metabolism and disposition, 1996-03, Vol.24 (3), p.273

1996

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Plasma vasopressin levels during hypoxaemia and the cardiovascular effects of exogenous vasopressin in foetal and adult sheep

The Journal of physiology, 1978-04, Vol.277 (1), p.341-357

Rurak, D W

1978

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Transplacental and nonplacental clearances, metabolism and pharmacodynamics of labetalol in the fetal lamb after direct intravenous administration

The Journal of pharmacology and experimental therapeutics, 1993-10, Vol.267 (1), p.425

1993

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Pharmacokinetics and pharmacodynamics of labetalol in the pregnant sheep

The Journal of pharmacology and experimental therapeutics, 1992-08, Vol.262 (2), p.683

1992

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Disposition, metabolism, and pharmacodynamics of labetalol in adult sheep

Drug metabolism and disposition, 1993-03, Vol.21 (2), p.284

1993

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Clearance and disposition of ritodrine in the fluid compartments of the fetal lamb during and after constant rate fetal intravenous infusion

The Journal of pharmacology and experimental therapeutics, 1991-09, Vol.258 (3), p.897

1991

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Increased oxygen consumption associated with breathing activity in fetal lambs

Journal of applied physiology (1985), 1983-03, Vol.54 (3), p.701-707

1983

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Fetal behavioral states: pathological alterations with drug/alcohol abuse

Seminars in perinatology, 1992-08, Vol.16 (4), p.239

Rurak, D W

1992

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Metabolic effects of ritodrine in the fetal lamb

The Journal of pharmacology and experimental therapeutics, 1992-07, Vol.262 (1), p.48

1992

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Ontogeny of valproic acid disposition and metabolism: a developmental study in postnatal lambs and adult sheep

Measurement of rest and activity in newborn lambs using actigraphy: studies in term and preterm lambs

Disposition of valproic acid in maternal, fetal, and newborn sheep. I: placental transfer, plasma protein binding, and clearance

Role of the liver and gut in systemic diphenhydramine clearance in adult nonpregnant sheep

Disposition of valproic acid in maternal, fetal, and newborn sheep. II: metabolism and renal elimination

Comparative formation, distribution, and elimination kinetics of diphenylmethoxyacetic acid (a diphenhydramine metabolite) in maternal and fetal sheep

Simultaneous determination of diphenhydramine, its N-oxide metabolite and their deuterium-labeled analogues in ovine plasma and urine using liquid chromatography/electrospray tandem mass spectrometry

Diphenhydramine disposition in the sheep maternal-placental-fetal unit: gestational age, plasma drug protein binding, and umbilical blood flow effects on clearance

Clearance and disposition of indometacin in chronically instrumented fetal lambs following a 3-day continuous intravenous infusion

Dose-dependent pharmacokinetics and metabolism of valproic acid in newborn lambs and adult sheep

The pharmacokinetics of valproic acid in pregnant sheep after maternal and fetal intravenous bolus administration

Blood volume restitution and growth in fetal lambs after acute hemorrhage

Diphenhydramine disposition in the sheep maternal–Placental–Fetal unit: Determinants of plasma drug concentrations in the mother and the fetus

Oxygen consumption in the fetal lamb during sustained hypoxemia with progressive acidemia

Blood flow and oxygen delivery to fetal organs and tissues during sustained hypoxemia

Oxygen consumption, acid-base status, and behavior during and after acute, severe hemorrhage in fetal lambs

Hepatic first-pass uptake of diphenhydramine. A comparative study between fetal and adult sheep

Plasma vasopressin levels during hypoxaemia and the cardiovascular effects of exogenous vasopressin in foetal and adult sheep

Transplacental and nonplacental clearances, metabolism and pharmacodynamics of labetalol in the fetal lamb after direct intravenous administration

Pharmacokinetics and pharmacodynamics of labetalol in the pregnant sheep

Disposition, metabolism, and pharmacodynamics of labetalol in adult sheep

Clearance and disposition of ritodrine in the fluid compartments of the fetal lamb during and after constant rate fetal intravenous infusion

Increased oxygen consumption associated with breathing activity in fetal lambs

Fetal behavioral states: pathological alterations with drug/alcohol abuse

Metabolic effects of ritodrine in the fetal lamb

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