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Profiling attention and cognition enhancing drugs in a rat touchscreen-based continuous performance test

Psychopharmacology, 2018-04, Vol.235 (4), p.1093-1105

2018

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Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: Relevance for neuropsychiatric disorders

Behavioural brain research, 2009-03, Vol.198 (1), p.83-90

2009

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Nicotinic modulation of auditory evoked potential electroencephalography in a rodent neurodevelopmental model of schizophrenia

Biochemical pharmacology, 2015-10, Vol.97 (4), p.482-487

2015

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Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist

The Journal of pharmacology and experimental therapeutics, 2005-04, Vol.313 (1), p.176

2005

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Structural abnormalities revealed by magnetic resonance imaging in rats prenatally exposed to methylazoxymethanol acetate parallel cerebral pathology in schizophrenia

Synapse (New York, N.Y.), 2011-05, Vol.65 (5), p.393-403

2011

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Behavioral characterization of a mutant mouse strain lacking d-amino acid oxidase activity

Behavioural brain research, 2011-02, Vol.217 (1), p.81-87

2011

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Predictive validity of a MK-801-induced cognitive impairment model in mice: Implications on the potential limitations and challenges of modeling cognitive impairment associated with schizophrenia preclinically

Progress in neuro-psychopharmacology & biological psychiatry, 2014-03, Vol.49, p.53-62

2014

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Enhancement of prepulse inhibition of startle in mice by the H3 receptor antagonists thioperamide and ciproxifan

Behavioural brain research, 2004-08, Vol.153 (1), p.69-76

2004

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Cross-site strain comparison of pharmacological deficits in the touchscreen visual discrimination test

Psychopharmacology, 2015-11, Vol.232 (21-22), p.4033-4041

2015

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The scopolamine model as a pharmacodynamic marker in early drug development

Psychopharmacologia, 2012-03, Vol.220 (1), p.97-107

2012

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Anticonvulsant effects of structurally diverse GABA(B) positive allosteric modulators in the DBA/2J audiogenic seizure test: Comparison to baclofen and utility as a pharmacodynamic screening model

Neuropharmacology, 2016-02, Vol.101, p.358-369

2016

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Treating the cognitive deficits of schizophrenia with alpha4beta2 neuronal nicotinic receptor agonists

Current pharmaceutical design, 2010-01, Vol.16 (3), p.309-322

2010

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Preclinical evaluation of non-imidazole histamine H3 receptor antagonists in comparison to atypical antipsychotics for the treatment of cognitive deficits associated with schizophrenia

The international journal of neuropsychopharmacology, 2013-05, Vol.16 (4), p.889-904

2013

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Effects of alpha 7 nicotinic acetylcholine receptor agonists on antipsychotic efficacy in a preclinical mouse model of psychosis

Psychopharmacology, 2012-04, Vol.220 (4), p.823-833

2012

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Effects of α7 nicotinic acetylcholine receptor agonists on antipsychotic efficacy in a preclinical mouse model of psychosis

Psychopharmacologia, 2012-04, Vol.220 (4), p.823-833

2012

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Vogel conflict test: Sex differences and pharmacological validation of the model

Behavioural brain research, 2011-03, Vol.218 (1), p.174-183

2011

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Discriminative-stimulus effects of NS9283, a nicotinic α4β2 positive allosteric modulator, in nicotine-discriminating rats

Psychopharmacology, 2014, Vol.231 (1), p.67-74

2014

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Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease

Brain research, 2010-01, Vol.1311, p.136-147

2010

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ABT-594 improves performance in the 5-choice serial reaction time task under conditions of increased difficulty, sub-chronic dosing, and in poorly-performing subjects

Pharmacology, biochemistry and behavior, 2010-04, Vol.95 (2), p.146-157

2010

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Chronic low dose risperidone and clozapine alleviate positive but not negative symptoms in the rat neonatal ventral hippocampal lesion model of schizophrenia

Psychopharmacologia, 2004-11, Vol.176 (3-4), p.312-319

2004

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Nicotinic acetylcholine receptor agonists: a potential new class of analgesics

Current topics in medicinal chemistry, 2004, Vol.4 (3), p.369-384

2004

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A microdialysis examination of serotonin release in the rat forebrain induced by behavioral/environmental manipulations

Brain research, 1996-11, Vol.739 (1-2), p.57-69

1996

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A-366833: A novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]-heptane α4β2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models

Biochemical pharmacology, 2007-10, Vol.74 (8), p.1253-1262

2007

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A-366833: A novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]- heptane alpha 4 beta 2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models

Biochemical pharmacology, 2007-10, Vol.74 (8), p.1253-1262

2007

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Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug-drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs

Brain research, 2005-05, Vol.1045 (1-2), p.142-149

2005

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Profiling attention and cognition enhancing drugs in a rat touchscreen-based continuous performance test

Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: Relevance for neuropsychiatric disorders

Nicotinic modulation of auditory evoked potential electroencephalography in a rodent neurodevelopmental model of schizophrenia

Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist

Structural abnormalities revealed by magnetic resonance imaging in rats prenatally exposed to methylazoxymethanol acetate parallel cerebral pathology in schizophrenia

Behavioral characterization of a mutant mouse strain lacking d-amino acid oxidase activity

Predictive validity of a MK-801-induced cognitive impairment model in mice: Implications on the potential limitations and challenges of modeling cognitive impairment associated with schizophrenia preclinically

Enhancement of prepulse inhibition of startle in mice by the H3 receptor antagonists thioperamide and ciproxifan

Cross-site strain comparison of pharmacological deficits in the touchscreen visual discrimination test

The scopolamine model as a pharmacodynamic marker in early drug development

Anticonvulsant effects of structurally diverse GABA(B) positive allosteric modulators in the DBA/2J audiogenic seizure test: Comparison to baclofen and utility as a pharmacodynamic screening model

Treating the cognitive deficits of schizophrenia with alpha4beta2 neuronal nicotinic receptor agonists

Preclinical evaluation of non-imidazole histamine H3 receptor antagonists in comparison to atypical antipsychotics for the treatment of cognitive deficits associated with schizophrenia

Effects of alpha 7 nicotinic acetylcholine receptor agonists on antipsychotic efficacy in a preclinical mouse model of psychosis

Effects of α7 nicotinic acetylcholine receptor agonists on antipsychotic efficacy in a preclinical mouse model of psychosis

Vogel conflict test: Sex differences and pharmacological validation of the model

Discriminative-stimulus effects of NS9283, a nicotinic α4β2 positive allosteric modulator, in nicotine-discriminating rats

Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease

ABT-594 improves performance in the 5-choice serial reaction time task under conditions of increased difficulty, sub-chronic dosing, and in poorly-performing subjects

Chronic low dose risperidone and clozapine alleviate positive but not negative symptoms in the rat neonatal ventral hippocampal lesion model of schizophrenia

Nicotinic acetylcholine receptor agonists: a potential new class of analgesics

A microdialysis examination of serotonin release in the rat forebrain induced by behavioral/environmental manipulations

A-366833: A novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]-heptane α4β2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models

A-366833: A novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]- heptane alpha 4 beta 2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models

Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug-drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs

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