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Phenotypic screening in cancer drug discovery - past, present and future

Nature reviews. Drug discovery, 2014-08, Vol.13 (8), p.588-602

2014

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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (14), p.5299-5304

2012

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Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α

Nature communications, 2021-12, Vol.12 (1), p.7310-7310, Article 7310

2021

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Dualität in der regelungstechnischen Methodenentwicklung

Automatisierungstechnik : AT, 2020-07, Vol.68 (7), p.541-556

Rudolph, Joachim

2020

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Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands

Nature communications, 2020-12, Vol.11 (1), p.6387-6387, Article 6387

2020

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Small-Molecule Ghrelin Receptor Antagonists Improve Glucose Tolerance, Suppress Appetite, and Promote Weight Loss

Endocrinology (Philadelphia), 2007-11, Vol.148 (11), p.5175-5185

2007

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NEURO-FUZZY OBSERVERS OF CLAMPING FORCE FOR MAGNETICALLY OPERATED MOVERS OF MOBILE ROBOTS

Tehnìčna elektrodinamìka, 2017-08, Vol.2017 (5), p.53-61

2017

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Redundante Koordinaten in der Modellbildung für ein schweres Seil

Automatisierungstechnik : AT, 2018-07, Vol.66 (7), p.536-547

2018

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Emerging Trends in Cancer Drug Discovery-From Drugging the "Undruggable" to Overcoming Resistance

Cancer discovery, 2021-04, Vol.11 (4), p.815-821

2021

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AlgDiff: an open source toolbox for the design, analysis and discretisation of algebraic differentiators

Automatisierungstechnik : AT, 2023-08, Vol.71 (8), p.612-623

2023

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Stabilisierung flacher Systeme in vorgebbarer endlicher Zeit

Automatisierungstechnik : AT, 2021-07, Vol.69 (7), p.585-596

2021

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seco-Cyclothialidines: New Concise Synthesis, Inhibitory Activity toward Bacterial and Human DNA Topoisomerases, and Antibacterial Properties

Journal of medicinal chemistry, 2001-02, Vol.44 (4), p.619-626

2001

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Output regulation for general heterodirectional linear hyperbolic PDEs coupled with nonlinear ODEs

Automatica (Oxford), 2023-02, Vol.148, p.110748, Article 110748

2023

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Selective Inhibition of Mutant Ras Protein through Covalent Binding

Angewandte Chemie (International ed.), 2014-04, Vol.53 (15), p.3777-3779

International ed. in English, 2014

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Highly Efficient Epoxidation of Olefins Using Aqueous H2O2 and Catalytic Methyltrioxorhenium/Pyridine: Pyridine-Mediated Ligand Acceleration

Journal of the American Chemical Society, 1997-07, Vol.119 (26), p.6189-6190

1997

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Systematic comparison of numerical differentiators and an application to model-free control

European journal of control, 2021-11, Vol.62, p.113-119

2021

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Survey on algebraic numerical differentiation: historical developments, parametrization, examples, and applications

International journal of systems science, 2022-07, Vol.53 (9), p.1848-1887

2022

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Beispiele für einen direkten Zugang zu einer globalen, energiebasierten Modellbildung und Regelung von Starrkörpersystemen

Automatisierungstechnik : AT, 2016-02, Vol.64 (2), p.96-109

2016

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Observer Design for Self-Sensing of Solenoid Actuators With Application to Soft Landing

IEEE transactions on control systems technology, 2019-07, Vol.27 (4), p.1720-1727

2019

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Total Synthesis of the Nematicidal Cyclododecapeptide Omphalotin A by Using Racemization-Free Triphosgene-Mediated Couplings in the Solid Phase

Angewandte Chemie (International ed.), 2002-07, Vol.41 (13), p.2307-2309

2002

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Inhibitors of p21-activated kinases (PAKs)

Journal of medicinal chemistry, 2015-01, Vol.58 (1), p.111-129

2015

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Triphosgene as highly efficient reagent for the solid-phase coupling of N-alkylated amino acids—total synthesis of cyclosporin O

Tetrahedron letters, 2002-07, Vol.43 (28), p.5013-5016

2002

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Expanding Chemical Probe Space: Quality Criteria for Covalent and Degrader Probes

Journal of medicinal chemistry, 2023-07, Vol.66 (14), p.9297-9312

2023

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Ras inhibition via direct Ras binding—is there a path forward?

Bioorganic & medicinal chemistry letters, 2012-09, Vol.22 (18), p.5766-5776

2012

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Control-oriented modelling and development of a model-based switching algorithm for a digital hydraulic independent metering cylinder drive

Proceedings of the Institution of Mechanical Engineers. Part I, Journal of systems and control engineering, 2017-02, Vol.231 (2), p.66-81

2017

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Phenotypic screening in cancer drug discovery - past, present and future

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α

Dualität in der regelungstechnischen Methodenentwicklung

Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands

Small-Molecule Ghrelin Receptor Antagonists Improve Glucose Tolerance, Suppress Appetite, and Promote Weight Loss

NEURO-FUZZY OBSERVERS OF CLAMPING FORCE FOR MAGNETICALLY OPERATED MOVERS OF MOBILE ROBOTS

Redundante Koordinaten in der Modellbildung für ein schweres Seil

Emerging Trends in Cancer Drug Discovery-From Drugging the "Undruggable" to Overcoming Resistance

AlgDiff: an open source toolbox for the design, analysis and discretisation of algebraic differentiators

Stabilisierung flacher Systeme in vorgebbarer endlicher Zeit

seco-Cyclothialidines: New Concise Synthesis, Inhibitory Activity toward Bacterial and Human DNA Topoisomerases, and Antibacterial Properties

Output regulation for general heterodirectional linear hyperbolic PDEs coupled with nonlinear ODEs

Selective Inhibition of Mutant Ras Protein through Covalent Binding

Highly Efficient Epoxidation of Olefins Using Aqueous H2O2 and Catalytic Methyltrioxorhenium/Pyridine: Pyridine-Mediated Ligand Acceleration

Systematic comparison of numerical differentiators and an application to model-free control

Survey on algebraic numerical differentiation: historical developments, parametrization, examples, and applications

Beispiele für einen direkten Zugang zu einer globalen, energiebasierten Modellbildung und Regelung von Starrkörpersystemen

Observer Design for Self-Sensing of Solenoid Actuators With Application to Soft Landing

Total Synthesis of the Nematicidal Cyclododecapeptide Omphalotin A by Using Racemization-Free Triphosgene-Mediated Couplings in the Solid Phase

Inhibitors of p21-activated kinases (PAKs)

Triphosgene as highly efficient reagent for the solid-phase coupling of N-alkylated amino acids—total synthesis of cyclosporin O

Expanding Chemical Probe Space: Quality Criteria for Covalent and Degrader Probes

Ras inhibition via direct Ras binding—is there a path forward?

Control-oriented modelling and development of a model-based switching algorithm for a digital hydraulic independent metering cylinder drive

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