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Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies

ACS nano, 2021-09, Vol.15 (9), p.14022-14048

2021

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Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals

Analytical chemistry (Washington), 2016-11, Vol.88 (21), p.10661-10666

2016

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CD44v6 Dependence of Premetastatic Niche Preparation by Exosomes

Neoplasia (New York, N.Y.), 2009-10, Vol.11 (10), p.1093,IN13-1105,IN17

2009

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Display of GPI‐anchored anti‐EGFR nanobodies on extracellular vesicles promotes tumour cell targeting

Journal of extracellular vesicles, 2016-01, Vol.5 (1), p.31053-n/a

2016

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Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy

Nature communications, 2017-06, Vol.8 (1), p.15507-15507, Article 15507

2017

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A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

Nature communications, 2017-09, Vol.8 (1), p.522-7, Article 522

2017

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The interplay between membrane topology and mechanical forces in regulating T cell receptor activity

Communications biology, 2022-01, Vol.5 (1), p.40-40, Article 40

2022

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Effect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer Activity

PloS one, 2015-10, Vol.10 (10), p.e0141088-e0141088

2015

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Pre-existing anti-polyethylene glycol antibody reduces the therapeutic efficacy and pharmacokinetics of PEGylated liposomes

Theranostics, 2018-01, Vol.8 (11), p.3164-3175

2018

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Structural basis of polyethylene glycol recognition by antibody

Journal of biomedical science, 2020-01, Vol.27 (1), p.12-12, Article 12

2020

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Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis

Pharmacological research, 2022-03, Vol.177, p.106115-106115, Article 106115

2022

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Reversible glycosidic switch for secure delivery of molecular nanocargos

Nature communications, 2018-05, Vol.9 (1), p.1843-13, Article 1843

2018

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Disruption of Scube2 Impairs Endochondral Bone Formation

Journal of bone and mineral research, 2015-07, Vol.30 (7), p.1255-1267

2015

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Flow cytometry analysis of anti-polyethylene glycol antibodies in human plasma

Toxicology reports, 2021-01, Vol.8, p.148-154

2021

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PEGylated Liposomal Methyl Prednisolone Succinate does not Induce Infusion Reactions in Patients: A Correlation Between in Vitro Immunological and in Vivo Clinical Studies

Molecules (Basel, Switzerland), 2020-01, Vol.25 (3), p.558

2020

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Sensitive Quantification of PEGylated Compounds by Second-Generation Anti-Poly(ethylene glycol) Monoclonal Antibodies

Bioconjugate chemistry, 2010-07, Vol.21 (7), p.1264-1270

2010

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Development of Irinotecan Liposome Armed with Dual-Target Anti-Epidermal Growth Factor Receptor and Anti-Fibroblast Activation Protein-Specific Antibody for Pancreatic Cancer Treatment

Pharmaceutics, 2022-06, Vol.14 (6), p.1202

2022

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High-Affinity Ligands Can Trigger T Cell Receptor Signaling Without CD45 Segregation

Frontiers in immunology, 2018-04, Vol.9, p.713-713

2018

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Interactions between nanoparticle corona proteins and the immune system

Current opinion in biotechnology, 2023-12, Vol.84, p.103010-103010, Article 103010

2023

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A Secondary Antibody-Detecting Molecular Weight Marker with Mouse and Rabbit IgG Fc Linear Epitopes for Western Blot Analysis

PloS one, 2016-08, Vol.11 (8), p.e0160418-e0160418

2016

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Double attack strategy for leukemia using a pre-targeting bispecific antibody (CD20 Ab-mPEG scFv) and actively attracting PEGylated liposomal doxorubicin to enhance anti-tumor activity

Journal of nanobiotechnology, 2021-01, Vol.19 (1), p.16-12, Article 16

2021

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Enhancement Effect of a Variable Topology of a Membrane-Tethered Anti-Poly(ethylene glycol) Antibody on the Sensitivity for Quantifying PEG and PEGylated Molecules

Analytical chemistry (Washington), 2017-06, Vol.89 (11), p.6082-6090

2017

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Premature Drug Release from Polyethylene Glycol (PEG)-Coated Liposomal Doxorubicin via Formation of the Membrane Attack Complex

ACS nano, 2020-07, Vol.14 (7), p.7808-7822

2020

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Targeting and internalizing PEGylated nanodrugs to enhance the therapeutic efficacy of hematologic malignancies by anti-PEG bispecific antibody (mPEG × CD20)

Cancer nanotechnology, 2023-12, Vol.14 (1), p.78-17, Article 78

2023

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High-throughput sorting of the highest producing cell via a transiently protein-anchored system

PloS one, 2014-07, Vol.9 (7), p.e102569-e102569

2014

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Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies

Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals

CD44v6 Dependence of Premetastatic Niche Preparation by Exosomes

Display of GPI‐anchored anti‐EGFR nanobodies on extracellular vesicles promotes tumour cell targeting

Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy

A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

The interplay between membrane topology and mechanical forces in regulating T cell receptor activity

Effect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer Activity

Pre-existing anti-polyethylene glycol antibody reduces the therapeutic efficacy and pharmacokinetics of PEGylated liposomes

Structural basis of polyethylene glycol recognition by antibody

Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis

Reversible glycosidic switch for secure delivery of molecular nanocargos

Disruption of Scube2 Impairs Endochondral Bone Formation

Flow cytometry analysis of anti-polyethylene glycol antibodies in human plasma

PEGylated Liposomal Methyl Prednisolone Succinate does not Induce Infusion Reactions in Patients: A Correlation Between in Vitro Immunological and in Vivo Clinical Studies

Sensitive Quantification of PEGylated Compounds by Second-Generation Anti-Poly(ethylene glycol) Monoclonal Antibodies

Development of Irinotecan Liposome Armed with Dual-Target Anti-Epidermal Growth Factor Receptor and Anti-Fibroblast Activation Protein-Specific Antibody for Pancreatic Cancer Treatment

High-Affinity Ligands Can Trigger T Cell Receptor Signaling Without CD45 Segregation

Interactions between nanoparticle corona proteins and the immune system

A Secondary Antibody-Detecting Molecular Weight Marker with Mouse and Rabbit IgG Fc Linear Epitopes for Western Blot Analysis

Double attack strategy for leukemia using a pre-targeting bispecific antibody (CD20 Ab-mPEG scFv) and actively attracting PEGylated liposomal doxorubicin to enhance anti-tumor activity

Enhancement Effect of a Variable Topology of a Membrane-Tethered Anti-Poly(ethylene glycol) Antibody on the Sensitivity for Quantifying PEG and PEGylated Molecules

Premature Drug Release from Polyethylene Glycol (PEG)-Coated Liposomal Doxorubicin via Formation of the Membrane Attack Complex

Targeting and internalizing PEGylated nanodrugs to enhance the therapeutic efficacy of hematologic malignancies by anti-PEG bispecific antibody (mPEG × CD20)

High-throughput sorting of the highest producing cell via a transiently protein-anchored system

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