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The need and benefit of immune monitoring to define patient and disease heterogeneity, mechanisms of therapeutic action and efficacy of intervention therapy for precision medicine in type 1 diabetes

Frontiers in immunology, 2023-01, Vol.14, p.1112858-1112858

Roep, Bart O

2023

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Distinct fecal and oral microbiota composition in human type 1 diabetes, an observational study

PloS one, 2017-12, Vol.12 (12), p.e0188475-e0188475

2017

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Immune checkpoint inhibitors and type 1 diabetes mellitus: a case report and systematic review

European journal of endocrinology, 2019-09, Vol.181 (3), p.363-374

2019

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Islet stress, degradation and autoimmunity

Diabetes, obesity & metabolism, 2018-09, Vol.20 (S2), p.88-94

2018

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Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes

Nature medicine, 2017-04, Vol.23 (4), p.501-507

2017

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Islet-Resident Dendritic Cells and Macrophages in Type 1 Diabetes: In Search of Bigfoot's Print

Frontiers in endocrinology (Lausanne), 2021-04, Vol.12, p.666795-666795

2021

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Low risk for diabetic complications in type 1 diabetes patients carrying a protective insulin gene variant

PloS one, 2023-01, Vol.18 (1), p.e0280872-e0280872

2023

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Induction of Treg by monocyte-derived DC modulated by vitamin D₃ or dexamethasone: Differential role for PD-L1

European journal of immunology, 2009-11, Vol.39 (11), p.3147-3159

2009

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Posttranslational modification of HLA-DQ binding islet autoantigens in type 1 diabetes

Diabetes (New York, N.Y.), 2014-01, Vol.63 (1), p.237-247

2014

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Functional Impact of Risk Gene Variants on the Autoimmune Responses in Type 1 Diabetes

Frontiers in immunology, 2022-05, Vol.13, p.886736-886736

2022

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Regulatory multitasking of tolerogenic dendritic cells - lessons taken from vitamin d3-treated tolerogenic dendritic cells

Frontiers in immunology, 2013-01, Vol.4, p.113-113

2013

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Tolerogenic dendritic cells pulsed with islet antigen induce long-term reduction in T-cell autoreactivity in type 1 diabetes patients

Frontiers in immunology, 2022-11, Vol.13, p.1054968-1054968

2022

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Activated Mesenchymal Stromal Cells Process and Present Antigens Regulating Adaptive Immunity

Frontiers in immunology, 2019-04, Vol.10, p.694-694

2019

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Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes

Diabetes (New York, N.Y.), 2005-01, Vol.54 (1), p.92-99

2005

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From Disease and Patient Heterogeneity to Precision Medicine in Type 1 Diabetes

Frontiers in medicine, 2022-07, Vol.9, p.932086-932086

2022

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Abnormal islet sphingolipid metabolism in type 1 diabetes

Diabetologia, 2018-07, Vol.61 (7), p.1650-1661

2018

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The vitamin D receptor gene FokI polymorphism: Functional impact on the immune system

European journal of immunology, 2007-02, Vol.37 (2), p.395-405

2007

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Chronic marijuana usage by human pancreas donors is associated with impaired islet function

PloS one, 2021-10, Vol.16 (10), p.e0258434

2021

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Surrogate end points in the design of immunotherapy trials: emerging lessons from type 1 diabetes

Nature reviews. Immunology, 2010-02, Vol.10 (2), p.145-152

2010

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Coxsackie B4 virus infection of β cells and natural killer cell insulitis in recent-onset type 1 diabetic patients

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (12), p.5115-5120

2007

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Immunogenicity of human embryonic stem cell-derived beta cells

Diabetologia, 2017-01, Vol.60 (1), p.126-133

2017

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Heterogeneity of circulating CD8 T-cells specific to islet, neo-antigen and virus in patients with type 1 diabetes mellitus

PloS one, 2018-08, Vol.13 (8), p.e0200818-e0200818

2018

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Induction of islet autoimmunity to defective ribosomal product of the insulin gene as neoantigen after anti-cancer immunotherapy leading to autoimmune diabetes

Frontiers in immunology, 2024-03, Vol.15, p.1384406-1384406

2024

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Translating Mechanism of Regulatory Action of Tolerogenic Dendritic Cells to Monitoring Endpoints in Clinical Trials

Frontiers in immunology, 2017-11, Vol.8, p.1598-1598

2017

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Defining Human Regulatory T Cells beyond FOXP3: The Need to Combine Phenotype with Function

Cells (Basel, Switzerland), 2024-06, Vol.13 (11), p.941

2024

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The need and benefit of immune monitoring to define patient and disease heterogeneity, mechanisms of therapeutic action and efficacy of intervention therapy for precision medicine in type 1 diabetes

Distinct fecal and oral microbiota composition in human type 1 diabetes, an observational study

Immune checkpoint inhibitors and type 1 diabetes mellitus: a case report and systematic review

Islet stress, degradation and autoimmunity

Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes

Islet-Resident Dendritic Cells and Macrophages in Type 1 Diabetes: In Search of Bigfoot's Print

Low risk for diabetic complications in type 1 diabetes patients carrying a protective insulin gene variant

Induction of Treg by monocyte-derived DC modulated by vitamin D₃ or dexamethasone: Differential role for PD-L1

Posttranslational modification of HLA-DQ binding islet autoantigens in type 1 diabetes

Functional Impact of Risk Gene Variants on the Autoimmune Responses in Type 1 Diabetes

Regulatory multitasking of tolerogenic dendritic cells - lessons taken from vitamin d3-treated tolerogenic dendritic cells

Tolerogenic dendritic cells pulsed with islet antigen induce long-term reduction in T-cell autoreactivity in type 1 diabetes patients

Activated Mesenchymal Stromal Cells Process and Present Antigens Regulating Adaptive Immunity

Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes

From Disease and Patient Heterogeneity to Precision Medicine in Type 1 Diabetes

Abnormal islet sphingolipid metabolism in type 1 diabetes

The vitamin D receptor gene FokI polymorphism: Functional impact on the immune system

Chronic marijuana usage by human pancreas donors is associated with impaired islet function

Surrogate end points in the design of immunotherapy trials: emerging lessons from type 1 diabetes

Coxsackie B4 virus infection of β cells and natural killer cell insulitis in recent-onset type 1 diabetic patients

Immunogenicity of human embryonic stem cell-derived beta cells

Heterogeneity of circulating CD8 T-cells specific to islet, neo-antigen and virus in patients with type 1 diabetes mellitus

Induction of islet autoimmunity to defective ribosomal product of the insulin gene as neoantigen after anti-cancer immunotherapy leading to autoimmune diabetes

Translating Mechanism of Regulatory Action of Tolerogenic Dendritic Cells to Monitoring Endpoints in Clinical Trials

Defining Human Regulatory T Cells beyond FOXP3: The Need to Combine Phenotype with Function

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