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Modulation of leukocyte genetic expression by novel purine nucleoside analogs. A new approach to antitumor and antiviral agents

Journal of medicinal chemistry, 1993-03, Vol.36 (6), p.635-653

1993

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Synthesis of 2'-deoxytubercidin, 2'-deoxyadenosine, and related 2'-deoxynucleosides via a novel direct stereospecific sodium salt glycosylation procedure

Journal of the American Chemical Society, 1984-10, Vol.106 (21), p.6379-6382

1984

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Induction of Megakaryocytic Differentiation and Modulation of Protein Kinase Gene Expression by Site-Selective cAMP Analogs in K-562 Human Leukemic Cells

Proceedings of the National Academy of Sciences - PNAS, 1989-04, Vol.86 (8), p.2849-2852

1989

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Broad-spectrum antiviral activity of 2-beta-D-ribofuranosylselenazole-4-carboxamide, a new antiviral agent

Antimicrobial Agents and Chemotherapy, 1983-09, Vol.24 (3), p.353-361

1983

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Reverse transformation of Harvey murine sarcoma virus-transformed NIH/3T3 cells by site-selective cyclic AMP analogs

The Journal of biological chemistry, 1988-01, Vol.263 (1), p.409-416

1988

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Aerosol and intraperitoneal administration of ribavirin and ribavirin triacetate: pharmacokinetics and protection of mice against intracerebral infection with influenza A/WSN virus

Antimicrobial Agents and Chemotherapy, 1991-07, Vol.35 (7), p.1448-1453

1991

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Synergistic antiviral effects of ribavirin and the C-nucleoside analogs tiazofurin and selenazofurin against togaviruses, bunyaviruses, and arenaviruses

Antimicrobial Agents and Chemotherapy, 1984-10, Vol.26 (4), p.476-480

1984

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2-.beta.-D-ribofuranosylthiazole-4-carboxamide, a novel potential antitumor agent for lung tumors and metastases

Journal of medicinal chemistry, 1982-02, Vol.25 (2), p.107-108

1982

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Structural Mimicry of Adenosine by the Antitumor Agents 4-methoxy- and 4-amino-8-(β -D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine as Viewed by a Molecular Modeling Method

Proceedings of the National Academy of Sciences - PNAS, 1989-11, Vol.86 (21), p.8242-8246

1989

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Broad-spectrum in vivo antiviral activity of 7-thia-8-oxoguanosine, a novel immunopotentiating agent

Antimicrobial Agents and Chemotherapy, 1989-09, Vol.33 (9), p.1487-1492

1989

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Inhibition of human pancreatic cancer cell (MIA PaCa-2) growth by cholera toxin and 8-chloro-cAMP in vitro

British journal of cancer, 1993-02, Vol.67 (2), p.279-283

1993

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Novel pyrazolo[3,4-d]pyrimidine nucleoside analog with broad-spectrum antiviral activity

Antimicrobial Agents and Chemotherapy, 1987-10, Vol.31 (10), p.1535-1541

1987

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Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-.beta.-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents

Journal of medicinal chemistry, 1990-01, Vol.33 (1), p.407-415

1990

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Site-selective cyclic AMP analogs provide a new approach in the control of cancer cell growth

FEBS letters, 1987-10, Vol.223 (1), p.97-103

1987

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Synthesis and biological evaluation of certain C-4 substituted pyrazolo[3,4-b]pyridine nucleosides

Journal of medicinal chemistry, 1989-05, Vol.32 (5), p.945-951

1989

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Synthesis of certain nucleoside methylenediphosphonate sugars as potential inhibitors of glycosyltransferases

Journal of medicinal chemistry, 1987-08, Vol.30 (8), p.1391-1399

1987

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Site-Selective cAMP Analogs at Micromolar Concentrations Induce Growth Arrest and Differentiation of Acute Promyelocytic, Chronic Myelocytic, and Acute Lymphocytic Human Leukemia Cell Lines

Blood, 1988-01, Vol.71 (1), p.230-233

1988

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Deoxycytidine Kinase-Mediated Toxicity of Deoxyadenosine Analogs toward Malignant Human Lymphoblasts in vitro and toward Murine L1210 Leukemia in vivo

Proceedings of the National Academy of Sciences - PNAS, 1980-11, Vol.77 (11), p.6865-6869

1980

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Synthesis and antiviral activity of certain guanosine analogs in the thiazolo[4,5-d]pyrimidine ring system

Journal of medicinal chemistry, 1991-10, Vol.34 (10), p.3006-3010

1991

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Polycytidylate and poly(7-deazaguanylate) : a pair of complementary templates

Journal of molecular evolution, 1994-03, Vol.38 (3), p.211-214

1994

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Synthesis of glycopyranosylphosphonate analogs of certain natural nucleoside diphosphate sugars as potential inhibitors of glycosyltransferases

Journal of medicinal chemistry, 1987-08, Vol.30 (8), p.1383-1391

1987

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Synthesis and antitumor evaluation in mice of certain 7-deazapurine (pyrrolo[2,3-d]pyrimidine) and 3-deazapurine (imidazo[4,5-c]pyridine) nucleosides structurally related to sulfenosine, sulfinosine, and sulfonosine

Journal of medicinal chemistry, 1990-04, Vol.33 (4), p.1220-1225

1990

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Purine analogs and related nucleosides and nucleotides as antitumor agents

Medicinal research reviews, 1985-07, Vol.5 (3), p.273-296

1985

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Synthesis and intramolecular hydrogen bonding and biochemical studies of clitocine, a naturally occurring exocyclic amino nucleoside

Journal of medicinal chemistry, 1988-04, Vol.31 (4), p.786-790

1988

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Biological activity of analogs of guanine and guanosine against American Trypanosoma and Leishmania spp

Antimicrobial Agents and Chemotherapy, 1987-03, Vol.31 (3), p.447-451

1987

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Modulation of leukocyte genetic expression by novel purine nucleoside analogs. A new approach to antitumor and antiviral agents

Synthesis of 2'-deoxytubercidin, 2'-deoxyadenosine, and related 2'-deoxynucleosides via a novel direct stereospecific sodium salt glycosylation procedure

Induction of Megakaryocytic Differentiation and Modulation of Protein Kinase Gene Expression by Site-Selective cAMP Analogs in K-562 Human Leukemic Cells

Broad-spectrum antiviral activity of 2-beta-D-ribofuranosylselenazole-4-carboxamide, a new antiviral agent

Reverse transformation of Harvey murine sarcoma virus-transformed NIH/3T3 cells by site-selective cyclic AMP analogs

Aerosol and intraperitoneal administration of ribavirin and ribavirin triacetate: pharmacokinetics and protection of mice against intracerebral infection with influenza A/WSN virus

Synergistic antiviral effects of ribavirin and the C-nucleoside analogs tiazofurin and selenazofurin against togaviruses, bunyaviruses, and arenaviruses

2-.beta.-D-ribofuranosylthiazole-4-carboxamide, a novel potential antitumor agent for lung tumors and metastases

Structural Mimicry of Adenosine by the Antitumor Agents 4-methoxy- and 4-amino-8-(β -D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine as Viewed by a Molecular Modeling Method

Broad-spectrum in vivo antiviral activity of 7-thia-8-oxoguanosine, a novel immunopotentiating agent

Inhibition of human pancreatic cancer cell (MIA PaCa-2) growth by cholera toxin and 8-chloro-cAMP in vitro

Novel pyrazolo[3,4-d]pyrimidine nucleoside analog with broad-spectrum antiviral activity

Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-.beta.-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents

Site-selective cyclic AMP analogs provide a new approach in the control of cancer cell growth

Synthesis and biological evaluation of certain C-4 substituted pyrazolo[3,4-b]pyridine nucleosides

Synthesis of certain nucleoside methylenediphosphonate sugars as potential inhibitors of glycosyltransferases

Site-Selective cAMP Analogs at Micromolar Concentrations Induce Growth Arrest and Differentiation of Acute Promyelocytic, Chronic Myelocytic, and Acute Lymphocytic Human Leukemia Cell Lines

Deoxycytidine Kinase-Mediated Toxicity of Deoxyadenosine Analogs toward Malignant Human Lymphoblasts in vitro and toward Murine L1210 Leukemia in vivo

Synthesis and antiviral activity of certain guanosine analogs in the thiazolo[4,5-d]pyrimidine ring system

Polycytidylate and poly(7-deazaguanylate) : a pair of complementary templates

Synthesis of glycopyranosylphosphonate analogs of certain natural nucleoside diphosphate sugars as potential inhibitors of glycosyltransferases

Synthesis and antitumor evaluation in mice of certain 7-deazapurine (pyrrolo[2,3-d]pyrimidine) and 3-deazapurine (imidazo[4,5-c]pyridine) nucleosides structurally related to sulfenosine, sulfinosine, and sulfonosine

Purine analogs and related nucleosides and nucleotides as antitumor agents

Synthesis and intramolecular hydrogen bonding and biochemical studies of clitocine, a naturally occurring exocyclic amino nucleoside

Biological activity of analogs of guanine and guanosine against American Trypanosoma and Leishmania spp

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