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Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity

British journal of cancer, 2003-11, Vol.89 (10), p.1971-1978

2003

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Imatinib mesylate and nilotinib (AMN107) exhibit high-affinity interaction with ABCG2 on primitive hematopoietic stem cells

Leukemia, 2007-06, Vol.21 (6), p.1267-1275

2007

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Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells

Cancer research (Chicago, Ill.), 2001-09, Vol.61 (18), p.6635-6639

2001

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Adaptive mesh refinement in the fast lane

Journal of computational physics, 2020-04, Vol.406 (C), p.109193, Article 109193

2020

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The linker region of breast cancer resistance protein ABCG2 is critical for coupling of ATP-dependent drug transport

Cellular and molecular life sciences : CMLS, 2016-05, Vol.73 (9), p.1927-1937

2016

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Overexpression of the ATP-binding Cassette Half-Transporter, ABCG2 (MXR/BCRP/ABCP1), in Flavopiridol-resistant Human Breast Cancer Cells

Clinical cancer research, 2001-01, Vol.7 (1), p.145-152

2001

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A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2)

Biochimica et biophysica acta, 2001-06, Vol.1512 (2), p.171-182

2001

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A high-throughput cell-based assay for inhibitors of ABCG2 activity

Journal of biomolecular screening, 2006-03, Vol.11 (2), p.176-183

2006

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Accompanying protein alterations in malignant cells with a microtubule-polymerizing drug-resistance phenotype and a primary resistance mechanism

Biochemical pharmacology, 2001-12, Vol.62 (11), p.1469-1480

2001

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The Calcium Channel Blockers, 1,4-Dihydropyridines, Are Substrates of the Multidrug Resistance-Linked ABC Drug Transporter, ABCG2

Biochemistry (Easton), 2006-07, Vol.45 (29), p.8940-8951

2006

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Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib

Drug metabolism and disposition, 2010-08, Vol.38 (8), p.1371-1380

2010

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Pheophorbide a is a specific probe for ABCG2 function and inhibition

Cancer research (Chicago, Ill.), 2004-02, Vol.64 (4), p.1242-1246

2004

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Phase I Trial of the Histone Deacetylase Inhibitor, Depsipeptide (FR901228, NSC 630176), in Patients with Refractory Neoplasms

Clinical cancer research, 2002-03, Vol.8 (3), p.718

2002

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ABCG2-mediated transport of photosensitizers: Potential impact on photodynamic therapy

Cancer biology & therapy, 2005-02, Vol.4 (2), p.195-202

2005

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Transport of methotrexate, methotrexate polyglutamates, and 17β-estradiol 17-(β-D-glucuronide) by ABCG2: Effects of acquired mutations at R482 on methotrexate transport

Cancer research (Chicago, Ill.), 2003-07, Vol.63 (14), p.4048-4054

2003

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T-cell lymphoma as a model for the use of histone deacetylase inhibitors in cancer therapy: impact of depsipeptide on molecular markers, therapeutic targets, and mechanisms of resistance

Blood, 2004-06, Vol.103 (12), p.4636-4643

2004

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Increased MDR1 Expression in Normal and Malignant Peripheral Blood Mononuclear Cells Obtained from Patients Receiving Depsipeptide (FR901228, FK228, NSC630176)

Clinical cancer research, 2006-03, Vol.12 (5), p.1547-1555

2006

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Overexpression of wild-type breast Cancer resistance protein mediates methotrexate resistance

Cancer research (Chicago, Ill.), 2002-09, Vol.62 (17), p.5035-5040

2002

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Chemoresistance in the clinic: overview 1994

Bulletin du cancer, 1994-12, Vol.81 Suppl 2, p.55s

1994

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Mutational Analysis of ABCG2: Role of the GXXXG Motif

Biochemistry (Easton), 2004-07, Vol.43 (29), p.9448-9456

2004

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ABCG2 mediates differential resistance to SN-38 (7-ethyl-10-hydroxycamptothecin) and homocamptothecins

The Journal of pharmacology and experimental therapeutics, 2004-08, Vol.310 (2), p.836-842

2004

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ABCG2 harboring the Gly482 mutation confers high-level resistance to various hydrophilic antifolates

Cancer research (Chicago, Ill.), 2005-09, Vol.65 (18), p.8414-8422

2005

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Normal p53 status and function despite the development of drug resistance in human breast cancer cells

Cell growth & differentiation, 1995-11, Vol.6 (11), p.1395-1403

1995

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Single-Nucleotide Polymorphism (SNP) Analysis in the ABC Half-Transporter ABCG2 (MXR/BCRP/ABCP1)

Cancer biology & therapy, 2002-11, Vol.1 (6), p.696-702

2002

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A Phase I/II Study of Infusional Vinblastine with the P-Glycoprotein Antagonist Valspodar (PSC 833) in Renal Cell Carcinoma

Clinical cancer research, 2004-07, Vol.10 (14), p.4724-4733

2004

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Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity

Imatinib mesylate and nilotinib (AMN107) exhibit high-affinity interaction with ABCG2 on primitive hematopoietic stem cells

Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells

Adaptive mesh refinement in the fast lane

The linker region of breast cancer resistance protein ABCG2 is critical for coupling of ATP-dependent drug transport

Overexpression of the ATP-binding Cassette Half-Transporter, ABCG2 (MXR/BCRP/ABCP1), in Flavopiridol-resistant Human Breast Cancer Cells

A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2)

A high-throughput cell-based assay for inhibitors of ABCG2 activity

Accompanying protein alterations in malignant cells with a microtubule-polymerizing drug-resistance phenotype and a primary resistance mechanism

The Calcium Channel Blockers, 1,4-Dihydropyridines, Are Substrates of the Multidrug Resistance-Linked ABC Drug Transporter, ABCG2

Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib

Pheophorbide a is a specific probe for ABCG2 function and inhibition

Phase I Trial of the Histone Deacetylase Inhibitor, Depsipeptide (FR901228, NSC 630176), in Patients with Refractory Neoplasms

ABCG2-mediated transport of photosensitizers: Potential impact on photodynamic therapy

Transport of methotrexate, methotrexate polyglutamates, and 17β-estradiol 17-(β-D-glucuronide) by ABCG2: Effects of acquired mutations at R482 on methotrexate transport

T-cell lymphoma as a model for the use of histone deacetylase inhibitors in cancer therapy: impact of depsipeptide on molecular markers, therapeutic targets, and mechanisms of resistance

Increased MDR1 Expression in Normal and Malignant Peripheral Blood Mononuclear Cells Obtained from Patients Receiving Depsipeptide (FR901228, FK228, NSC630176)

Overexpression of wild-type breast Cancer resistance protein mediates methotrexate resistance

Chemoresistance in the clinic: overview 1994

Mutational Analysis of ABCG2: Role of the GXXXG Motif

ABCG2 mediates differential resistance to SN-38 (7-ethyl-10-hydroxycamptothecin) and homocamptothecins

ABCG2 harboring the Gly482 mutation confers high-level resistance to various hydrophilic antifolates

Normal p53 status and function despite the development of drug resistance in human breast cancer cells

Single-Nucleotide Polymorphism (SNP) Analysis in the ABC Half-Transporter ABCG2 (MXR/BCRP/ABCP1)

A Phase I/II Study of Infusional Vinblastine with the P-Glycoprotein Antagonist Valspodar (PSC 833) in Renal Cell Carcinoma

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