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Glycogen and its metabolism: some new developments and old themes

Biochemical journal, 2012-02, Vol.441 (3), p.763-787

2012

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Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter

Science (American Association for the Advancement of Science), 2008-10, Vol.322 (5902), p.709-713

2008

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Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase

Journal of medicinal chemistry, 2020-04, Vol.63 (7), p.3538-3551

2020

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Phosphate Incorporation during Glycogen Synthesis and Lafora Disease

Cell metabolism, 2011-03, Vol.13 (3), p.274-282

2011

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PTG depletion removes Lafora bodies and rescues the fatal epilepsy of Lafora disease

PLoS genetics, 2011-04, Vol.7 (4), p.e1002037-e1002037

2011

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Genetic Depletion of the Malin E3 Ubiquitin Ligase in Mice Leads to Lafora Bodies and the Accumulation of Insoluble Laforin

The Journal of biological chemistry, 2010-08, Vol.285 (33), p.25372-25381

2010

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The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex

Cell reports (Cambridge), 2022-07, Vol.40 (1), p.111041-111041, Article 111041

2022

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Abnormal Metabolism of Glycogen Phosphate as a Cause for Lafora Disease

The Journal of biological chemistry, 2008-12, Vol.283 (49), p.33816-33825

2008

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Starch Binding Domain-containing Protein 1/Genethonin 1 Is a Novel Participant in Glycogen Metabolism

The Journal of biological chemistry, 2010-11, Vol.285 (45), p.34960-34971

2010

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Glycogen Phosphomonoester Distribution in Mouse Models of the Progressive Myoclonic Epilepsy, Lafora Disease

The Journal of biological chemistry, 2015-01, Vol.290 (2), p.841-850

2015

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Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo

Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (49), p.19262-19266

2007

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Inhibiting glycogen synthesis prevents lafora disease in a mouse model

Annals of neurology, 2013-08, Vol.74 (2), p.297-300

2013

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AMPK → ULK1 → Autophagy

Molecular and cellular biology, 2011-08, Vol.31 (15), p.3082-3084

Roach, Peter J.

2011

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Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation

Cell reports (Cambridge), 2019-11, Vol.29 (6), p.1410-1418.e6

2019

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Structural basis for glucose-6-phosphate activation of glycogen synthase

Proceedings of the National Academy of Sciences - PNAS, 2010-10, Vol.107 (41), p.17563-17568

2010

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Glycogen phosphorylation and Lafora disease

Molecular aspects of medicine, 2015-12, Vol.46, p.78-84

Roach, Peter J.

2015

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Structural basis for 2′-phosphate incorporation into glycogen by glycogen synthase

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (52), p.20976-20981

2013

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Impaired Glucose Tolerance and Predisposition to the Fasted State in Liver Glycogen Synthase Knock-out Mice

The Journal of biological chemistry, 2010-04, Vol.285 (17), p.12851-12861

2010

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GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease

Annals of clinical and translational neurology, 2020-11, Vol.7 (11), p.2186-2198

2020

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Glucose Metabolism in Mice Lacking Muscle Glycogen Synthase

Diabetes (New York, N.Y.), 2005-12, Vol.54 (12), p.3466-3473

2005

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Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1

Biochemical and biophysical research communications, 2011-09, Vol.413 (3), p.420-425

2011

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Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen

The Journal of biological chemistry, 2011-09, Vol.286 (39), p.33999-34006

2011

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Abnormal Cardiac Development in the Absence of Heart Glycogen

Molecular and Cellular Biology, 2004-08, Vol.24 (16), p.7179-7187

2004

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Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice

The Journal of biological chemistry, 2017-06, Vol.292 (25), p.10455-10464

2017

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Lafora disease offers a unique window into neuronal glycogen metabolism

The Journal of biological chemistry, 2018-05, Vol.293 (19), p.7117-7125

2018

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Glycogen and its metabolism: some new developments and old themes

Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter

Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase

Phosphate Incorporation during Glycogen Synthesis and Lafora Disease

PTG depletion removes Lafora bodies and rescues the fatal epilepsy of Lafora disease

Genetic Depletion of the Malin E3 Ubiquitin Ligase in Mice Leads to Lafora Bodies and the Accumulation of Insoluble Laforin

The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex

Abnormal Metabolism of Glycogen Phosphate as a Cause for Lafora Disease

Starch Binding Domain-containing Protein 1/Genethonin 1 Is a Novel Participant in Glycogen Metabolism

Glycogen Phosphomonoester Distribution in Mouse Models of the Progressive Myoclonic Epilepsy, Lafora Disease

Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo

Inhibiting glycogen synthesis prevents lafora disease in a mouse model

AMPK → ULK1 → Autophagy

Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation

Structural basis for glucose-6-phosphate activation of glycogen synthase

Glycogen phosphorylation and Lafora disease

Structural basis for 2′-phosphate incorporation into glycogen by glycogen synthase

Impaired Glucose Tolerance and Predisposition to the Fasted State in Liver Glycogen Synthase Knock-out Mice

GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease

Glucose Metabolism in Mice Lacking Muscle Glycogen Synthase

Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1

Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen

Abnormal Cardiac Development in the Absence of Heart Glycogen

Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice

Lafora disease offers a unique window into neuronal glycogen metabolism

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