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Thymidylate Synthase and Methylenetetrahydrofolate Reductase Gene Polymorphisms and Toxicity to Capecitabine in Advanced Colorectal Cancer Patients

Clinical cancer research, 2008-02, Vol.14 (3), p.817-825

2008

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Sequence determinants of innate immune activation by short interfering RNAs

BMC immunology, 2009-07, Vol.10 (1), p.40-40

2009

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Transcriptional Repression of Hepatic Cytochrome P450 3A4 Gene in the Presence of Cancer

Clinical cancer research, 2006-12, Vol.12 (24), p.7492-7497

2006

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Factors Affecting Cytochrome P-450 3A Activity in Cancer Patients

Clinical cancer research, 2004-12, Vol.10 (24), p.8341-8350

2004

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Predictors of Vinorelbine Pharmacokinetics and Pharmacodynamics in Patients With Cancer

Journal of clinical oncology, 2006-06, Vol.24 (16), p.2448-2455

2006

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Intended transcriptional silencing with siRNA results in gene repression through sequence-specific off-targeting

RNA (Cambridge), 2010-02, Vol.16 (2), p.430-441

2010

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Inflammatory response: an unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy

The lancet oncology, 2003-04, Vol.4 (4), p.224-232

2003

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The erythromycin breath test for the prediction of drug clearance

Clinical pharmacokinetics, 2001, Vol.40 (3), p.151-158

2001

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Rapid quantitation of plasma 2/-deoxyuridine by high-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometry and its application to pharmacodynamic studies in cancer patients

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005-06, Vol.820 (1), p.121-130

2005

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The hepatic sinusoid in aging and cirrhosis: Effects on hepatic substrate disposition and drug clearance

Clinical pharmacokinetics, 2005-01, Vol.44 (2), p.187-200

2005

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Interfering ribonucleic acids that suppress expression of multiple unrelated genes

BMC biotechnology, 2009-06, Vol.9 (57), p.57-57

2009

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Quantitation of plasma thymidine by high-performance liquid chromatography—atmospheric pressure chemical ionization mass spectrometry and its application to pharmacodynamic studies in cancer patients

Analytica chimica acta, 2003-06, Vol.486 (1), p.51-61

2003

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Hepatic Technetium Tc 99m–labeled Sestamibi Elimination Rate and ABCB1 (MDR1) Genotype as Indicators of ABCB1 (P–glycoprotein) Activity in Patients with Cancer

Clinical pharmacology and therapeutics, 2005-01, Vol.77 (1), p.33-42

2005

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The importance of tumor glucuronidase in the activation of irinotecan in a mouse xenograft model

The Journal of pharmacology and experimental therapeutics, 2002-11, Vol.303 (2), p.649-655

2002

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Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38), by Human Liver Carboxylesterase

Biochemical pharmacology, 1996-10, Vol.52 (7), p.1103-1111

1996

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A pilot study on the safety of combining chrysin, a non-absorbable inducer of UGT1A1, and irinotecan (CPT-11) to treat metastatic colorectal cancer

Cancer chemotherapy and pharmacology, 2006-03, Vol.57 (3), p.309-316

2006

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Population pharmacokinetics of weekly docetaxel in patients with advanced cancer

British journal of clinical pharmacology, 2004-01, Vol.57 (1), p.44-53

2004

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Inhibition of Topoisomerase I Cleavage Activity by Thiol-reactive Compounds: IMPORTANCE OF VICINAL CYSTEINES 504 AND 505

The Journal of biological chemistry, 2007-05, Vol.282 (19), p.14403-14412

2007

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Baseline Nutritional Assessment in Advanced Cancer Patients Receiving Palliative Chemotherapy

Nutrition and cancer, 2003-01, Vol.46 (2), p.148-157

2003

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Solid-Phase Extraction (SPE) Techniques for Sample Preparation in Clinical and Pharmaceutical Analysis: A Brief Overview

Current pharmaceutical analysis, 2006-05, Vol.2 (2), p.95-102

2006

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Predicting the toxicity of weekly docetaxel in advanced cancer

Clinical pharmacokinetics, 2006-01, Vol.45 (6), p.611-622

2006

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The Mechanism for the Inhibition of Acetylcholinesterases by Irinotecan (CPT-11)

Molecular pharmacology, 1999-12, Vol.56 (6), p.1346-1353

1999

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Identification of a new metabolite of CPT-11 (irinotecan): pharmacological properties and activation to SN-38

The Journal of pharmacology and experimental therapeutics, 1998-07, Vol.286 (1), p.578

1998

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Altered deoxyuridine and thymidine in plasma following capecitabine treatment in colorectal cancer patients

British journal of clinical pharmacology, 2007-01, Vol.63 (1), p.67-74

2007

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Identification and properties of a major plasma metabolite of irinotecan (CPT-11) isolated from the plasma of patients

Cancer research (Chicago, Ill.), 1996-08, Vol.56 (16), p.3689-3694

1996

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Thymidylate Synthase and Methylenetetrahydrofolate Reductase Gene Polymorphisms and Toxicity to Capecitabine in Advanced Colorectal Cancer Patients

Sequence determinants of innate immune activation by short interfering RNAs

Transcriptional Repression of Hepatic Cytochrome P450 3A4 Gene in the Presence of Cancer

Factors Affecting Cytochrome P-450 3A Activity in Cancer Patients

Predictors of Vinorelbine Pharmacokinetics and Pharmacodynamics in Patients With Cancer

Intended transcriptional silencing with siRNA results in gene repression through sequence-specific off-targeting

Inflammatory response: an unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy

The erythromycin breath test for the prediction of drug clearance

Rapid quantitation of plasma 2/-deoxyuridine by high-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometry and its application to pharmacodynamic studies in cancer patients

The hepatic sinusoid in aging and cirrhosis: Effects on hepatic substrate disposition and drug clearance

Interfering ribonucleic acids that suppress expression of multiple unrelated genes

Quantitation of plasma thymidine by high-performance liquid chromatography—atmospheric pressure chemical ionization mass spectrometry and its application to pharmacodynamic studies in cancer patients

Hepatic Technetium Tc 99m–labeled Sestamibi Elimination Rate and ABCB1 (MDR1) Genotype as Indicators of ABCB1 (P–glycoprotein) Activity in Patients with Cancer

The importance of tumor glucuronidase in the activation of irinotecan in a mouse xenograft model

Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38), by Human Liver Carboxylesterase

A pilot study on the safety of combining chrysin, a non-absorbable inducer of UGT1A1, and irinotecan (CPT-11) to treat metastatic colorectal cancer

Population pharmacokinetics of weekly docetaxel in patients with advanced cancer

Inhibition of Topoisomerase I Cleavage Activity by Thiol-reactive Compounds: IMPORTANCE OF VICINAL CYSTEINES 504 AND 505

Baseline Nutritional Assessment in Advanced Cancer Patients Receiving Palliative Chemotherapy

Solid-Phase Extraction (SPE) Techniques for Sample Preparation in Clinical and Pharmaceutical Analysis: A Brief Overview

Predicting the toxicity of weekly docetaxel in advanced cancer

The Mechanism for the Inhibition of Acetylcholinesterases by Irinotecan (CPT-11)

Identification of a new metabolite of CPT-11 (irinotecan): pharmacological properties and activation to SN-38

Altered deoxyuridine and thymidine in plasma following capecitabine treatment in colorectal cancer patients

Identification and properties of a major plasma metabolite of irinotecan (CPT-11) isolated from the plasma of patients

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