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Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation

Proceedings of the National Academy of Sciences - PNAS, 2016-06, Vol.113 (24), p.E3441-E3450

2016

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Peripheral Cannabinoid-1 Receptor Inverse Agonism Reduces Obesity by Reversing Leptin Resistance

Cell metabolism, 2012-08, Vol.16 (2), p.167-179

2012

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The “Toll” of Opioid-Induced Glial Activation: Improving the Clinical Efficacy of Opioids by Targeting Glia

Trends in pharmacological sciences (Regular ed.), 2009-11, Vol.30 (11), p.581-591

2009

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Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia

Nature chemical biology, 2011-05, Vol.7 (5), p.296

2011

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Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats

Brain, behavior, and immunity, 2018-08, Vol.72, p.45-50

2018

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Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (45), p.11597-11602

2018

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Structure–Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists

Journal of medicinal chemistry, 2015-06, Vol.58 (12), p.5038-5052

2015

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Effects of Selective and Mixed-Action Kappa and Delta Opioid Receptor Agonists on Pain-Related Behavioral Depression in Mice

Molecules (Basel, Switzerland), 2024-07, Vol.29 (14), p.3331

2024

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Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy- N -phenethyl-5-phenylmorphans

Molecules (Basel, Switzerland), 2024-04, Vol.29 (9), p.1926

2024

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Targeting the Toll of Drug Abuse: The Translational Potential of Toll-Like Receptor 4

CNS & neurological disorders drug targets, 2015-01, Vol.14 (6), p.692

2015

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Potent MOR Agonists from 2'-Hydroxy-5,9-dimethyl- N -phenethyl Substituted-6,7-benzomorphans and from C8-Hydroxy, Methylene and Methyl Derivatives of N -Phenethylnormetazocine

Molecules (Basel, Switzerland), 2023-11, Vol.28 (23), p.7709

2023

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CRF system recruitment mediates dark side of compulsive eating

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (47), p.20016-20020

2009

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Toll-Like Receptor 4 Is an Essential Upstream Regulator of On-Time Parturition and Perinatal Viability in Mice

Endocrinology (Philadelphia), 2015-10, Vol.156 (10), p.3828-3841

2015

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Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans

Molecules (Basel, Switzerland), 2023-06, Vol.28 (12), p.4795

2023

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Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (16), p.6277-6282

2012

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Corticotropin-Releasing Factor 1 Antagonists Selectively Reduce Ethanol Self-Administration in Ethanol-Dependent Rats

Biological psychiatry (1969), 2007-01, Vol.61 (1), p.78-86

2007

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Visualizing endogenous opioid receptors in living neurons using ligand-directed chemistry

eLife, 2019-10, Vol.8

2019

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Individual Differences in Impulsive Action Reflect Variation in the Cortical Serotonin 5-HT2A Receptor System

Neuropsychopharmacology (New York, N.Y.), 2015-07, Vol.40 (8), p.1957-1968

2015

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A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits

Frontiers in neuroscience, 2015-12, Vol.9, p.487

2015

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Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans

Molecules (Basel, Switzerland), 2022-12, Vol.27 (24), p.8808

2022

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A Journey through Diastereomeric Space: The Design, Synthesis, In Vitro and In Vivo Pharmacological Activity, and Molecular Modeling of Novel Potent Diastereomeric MOR Agonists and Antagonists

Molecules (Basel, Switzerland), 2022-09, Vol.27 (19), p.6455

2022

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Epidermal adrenergic signaling contributes to inflammation and pain sensitization in a rat model of complex regional pain syndrome

Pain (Amsterdam), 2013-08, Vol.154 (8), p.1224-1236

2013

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3,4-Methylenedioxymethamphetamine Increases Affiliative Behaviors in Squirrel Monkeys in a Serotonin 2A Receptor-Dependent Manner

Neuropsychopharmacology (New York, N.Y.), 2017-09, Vol.42 (10), p.1962-1971

2017

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Design, Synthesis, and In Vivo Evaluation of C1-Linked 4,5-Epoxymorphinan Haptens for Heroin Vaccines

Molecules (Basel, Switzerland), 2022-02, Vol.27 (5), p.1553

2022

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Novel chimeric monoclonal antibodies that block fentanyl effects and alter fentanyl biodistribution in mice

mAbs, 2021-01, Vol.13 (1), p.1991552

2021

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Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation

Peripheral Cannabinoid-1 Receptor Inverse Agonism Reduces Obesity by Reversing Leptin Resistance

The “Toll” of Opioid-Induced Glial Activation: Improving the Clinical Efficacy of Opioids by Targeting Glia

Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia

Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats

Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist

Structure–Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists

Effects of Selective and Mixed-Action Kappa and Delta Opioid Receptor Agonists on Pain-Related Behavioral Depression in Mice

Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy- N -phenethyl-5-phenylmorphans

Targeting the Toll of Drug Abuse: The Translational Potential of Toll-Like Receptor 4

Potent MOR Agonists from 2'-Hydroxy-5,9-dimethyl- N -phenethyl Substituted-6,7-benzomorphans and from C8-Hydroxy, Methylene and Methyl Derivatives of N -Phenethylnormetazocine

CRF system recruitment mediates dark side of compulsive eating

Toll-Like Receptor 4 Is an Essential Upstream Regulator of On-Time Parturition and Perinatal Viability in Mice

Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans

Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation

Corticotropin-Releasing Factor 1 Antagonists Selectively Reduce Ethanol Self-Administration in Ethanol-Dependent Rats

Visualizing endogenous opioid receptors in living neurons using ligand-directed chemistry

Individual Differences in Impulsive Action Reflect Variation in the Cortical Serotonin 5-HT2A Receptor System

A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits

Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans

A Journey through Diastereomeric Space: The Design, Synthesis, In Vitro and In Vivo Pharmacological Activity, and Molecular Modeling of Novel Potent Diastereomeric MOR Agonists and Antagonists

Epidermal adrenergic signaling contributes to inflammation and pain sensitization in a rat model of complex regional pain syndrome

3,4-Methylenedioxymethamphetamine Increases Affiliative Behaviors in Squirrel Monkeys in a Serotonin 2A Receptor-Dependent Manner

Design, Synthesis, and In Vivo Evaluation of C1-Linked 4,5-Epoxymorphinan Haptens for Heroin Vaccines

Novel chimeric monoclonal antibodies that block fentanyl effects and alter fentanyl biodistribution in mice

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