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Structure and function of bacterial transcription regulators of the SorC family

Transcription, 2024-09, p.1-22

2024

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N-Glycosylation can selectively block or foster different receptor–ligand binding modes

Scientific reports, 2021-03, Vol.11 (1), p.5239-5239, Article 5239

2021

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QM/MM Calculations Reveal the Different Nature of the Interaction of Two Carborane-Based Sulfamide Inhibitors of Human Carbonic Anhydrase II

The journal of physical chemistry. B, 2013-12, Vol.117 (50), p.16096-16104

2013

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3,5,7-Substituted Pyrazolo[4,3‑d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders

Journal of medicinal chemistry, 2022-07, Vol.65 (13), p.8881-8896

2022

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Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7‑Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists

Journal of medicinal chemistry, 2022-10, Vol.65 (20), p.14082-14103

2022

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Structural characterization of two prototypical repressors of SorC family reveals tetrameric assemblies on DNA and mechanism of function

Nucleic acids research, 2024-07, Vol.52 (12), p.7305-7320

2024

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Validation and structural characterization of the LEDGF/p75-MLL interface as a new target for the treatment of MLL-dependent leukemia

Cancer research (Chicago, Ill.), 2014-09, Vol.74 (18), p.5139-5151

2014

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ABNOH‐Linked Nucleotides and DNA for Bioconjugation and Cross‐linking with Tryptophan‐Containing Peptides and Proteins

Chemistry : a European journal, 2024-09, Vol.30 (49), p.e202402151-n/a

2024

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3H‑Pyrazolo[4,3‑f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo

Journal of medicinal chemistry, 2021-08, Vol.64 (15), p.10981-10996

2021

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Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds

Chembiochem : a European journal of chemical biology, 2021-09, Vol.22 (18), p.2741-2761

2021

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Crystal structure of blue laccase BP76, a unique termite suicidal defense weapon

Structure (London), 2024-10, Vol.32 (10), p.1581-1585.e5

2024

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Engineering Enzyme Stability and Resistance to an Organic Cosolvent by Modification of Residues in the Access Tunnel

Angewandte Chemie International Edition, 2013-02, Vol.52 (7), p.1959-1963

International ed. in English, 2013

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Structure-Aided Design of Novel Inhibitors of HIV Protease Based on a Benzodiazepine Scaffold

Journal of medicinal chemistry, 2012-11, Vol.55 (22), p.10130-10135

2012

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Structural insight into DNA recognition by bacterial transcriptional regulators of the SorC/DeoR family

Acta crystallographica. Section D, Biological crystallography., 2021-11, Vol.77 (11), p.1411-1424

2021

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An evolutionary molecular adaptation of an unusual stefin from the liver fluke Fasciola hepatica redefines the cystatin superfamily

The Journal of biological chemistry, 2023-03, Vol.299 (3), p.102970-102970, Article 102970

2023

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Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation

Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (30), p.E7053-E7062

2018

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Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7

Biomedicine & pharmacotherapy, 2023-05, Vol.161, p.114492-114492, Article 114492

2023

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Thermodynamic and structural analysis of HIV protease resistance to darunavir – analysis of heavily mutated patient‐derived HIV‐1 proteases

The FEBS journal, 2014-04, Vol.281 (7), p.1834-1847

2014

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Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif

Nature communications, 2015-08, Vol.6 (1), p.7968-7968, Article 7968

2015

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Carborane-Based Carbonic Anhydrase Inhibitors

Angewandte Chemie International Edition, 2013-12, Vol.52 (51), p.13760-13763

International ed. in English, 2013

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Rutinosidase from Aspergillus niger: crystal structure and insight into the enzymatic activity

The FEBS journal, 2020-08, Vol.287 (15), p.3315-3327

2020

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3,5,7-Substituted Pyrazolo[4,3‑d]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models

Journal of medicinal chemistry, 2019-05, Vol.62 (9), p.4606-4623

2019

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Mialostatin, a Novel Midgut Cystatin from Ixodes ricinus Ticks: Crystal Structure and Regulation of Host Blood Digestion

International journal of molecular sciences, 2021-05, Vol.22 (10), p.5371

2021

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A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation

Blood, 2011-01, Vol.117 (2), p.736-744

2011

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B-H π and C-H π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides

Physical chemistry chemical physics : PCCP, 2023-01, Vol.25 (3), p.1728-1733

2023

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Structure and function of bacterial transcription regulators of the SorC family

N-Glycosylation can selectively block or foster different receptor–ligand binding modes

QM/MM Calculations Reveal the Different Nature of the Interaction of Two Carborane-Based Sulfamide Inhibitors of Human Carbonic Anhydrase II

3,5,7-Substituted Pyrazolo[4,3‑d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders

Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7‑Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists

Structural characterization of two prototypical repressors of SorC family reveals tetrameric assemblies on DNA and mechanism of function

Validation and structural characterization of the LEDGF/p75-MLL interface as a new target for the treatment of MLL-dependent leukemia

ABNOH‐Linked Nucleotides and DNA for Bioconjugation and Cross‐linking with Tryptophan‐Containing Peptides and Proteins

3H‑Pyrazolo[4,3‑f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo

Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds

Crystal structure of blue laccase BP76, a unique termite suicidal defense weapon

Engineering Enzyme Stability and Resistance to an Organic Cosolvent by Modification of Residues in the Access Tunnel

Structure-Aided Design of Novel Inhibitors of HIV Protease Based on a Benzodiazepine Scaffold

Structural insight into DNA recognition by bacterial transcriptional regulators of the SorC/DeoR family

An evolutionary molecular adaptation of an unusual stefin from the liver fluke Fasciola hepatica redefines the cystatin superfamily

Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation

Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7

Thermodynamic and structural analysis of HIV protease resistance to darunavir – analysis of heavily mutated patient‐derived HIV‐1 proteases

Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif

Carborane-Based Carbonic Anhydrase Inhibitors

Rutinosidase from Aspergillus niger: crystal structure and insight into the enzymatic activity

3,5,7-Substituted Pyrazolo[4,3‑d]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models

Mialostatin, a Novel Midgut Cystatin from Ixodes ricinus Ticks: Crystal Structure and Regulation of Host Blood Digestion

A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation

B-H π and C-H π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides

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