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Discovery of a Potent and Selective Inhibitor of Cyclin-Dependent Kinase 4/6

Journal of medicinal chemistry, 2005-04, Vol.48 (7), p.2388-2406

2005

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Renin inhibitors containing isosteric replacements of the amide bond connecting the P3 and P2 sites

Journal of medicinal chemistry, 1990-02, Vol.33 (2), p.838-845

1990

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Structure−Activity Relationships in a Series of Orally Active γ-Hydroxy Butenolide Endothelin Antagonists

Journal of medicinal chemistry, 1997-03, Vol.40 (7), p.1063-1074

1997

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Butenolide Endothelin Antagonists with Improved Aqueous Solubility

Journal of medicinal chemistry, 1999-06, Vol.42 (12), p.2162-2168

1999

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Renin inhibitors containing .alpha.-heteroatom amino acids as P2 residues

Journal of medicinal chemistry, 1992-03, Vol.35 (6), p.1032-1042

1992

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Design, synthesis and solution structure of a renin inhibitor Structural constraints from NOE, and homonuclear and heteronuclear coupling constants combined with distance geometry calculations

FEBS letters, 1992-05, Vol.302 (1), p.97-103

1992

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Renin inhibitors containing esters at the P2-position. Oral activity in a derivative of methyl aminomalonate

Journal of medicinal chemistry, 1991-07, Vol.34 (7), p.1935-1943

1991

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Modified di- and tripeptides of the C-terminal portion of oxytocin and vasopressin as possible cognition activation agents

Journal of medicinal chemistry, 1986-06, Vol.29 (6), p.959-971

1986

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Pyrido[2,3-d]pyrimidin-7-ones as Specific Inhibitors of Cyclin-Dependent Kinase 4

Journal of medicinal chemistry, 2005-04, Vol.48 (7), p.2371-2387

2005

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Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors

Journal of medicinal chemistry, 1993-11, Vol.36 (24), p.3809-3820

1993

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New inhibitors of human renin that contain novel replacements at the P2 site

Journal of medicinal chemistry, 1991-04, Vol.34 (4), p.1258-1271

1991

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Psi [CH2NH] backbone-modified peptides: first unequivocal observation of a C7 structure in a linear peptide

Peptide research, 1989-09, Vol.2 (5), p.332

1989

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γ-Carbamate butenolide analogues as potent ETA selective endothelin receptor antagonists and prodrugs

Bioorganic & medicinal chemistry letters, 1997-02, Vol.7 (3), p.297-302

1997

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New inhibitors of human renin that contain novel replacements at the P sub(2) site

Journal of medicinal chemistry, 1991-01, Vol.34 (4), p.1258-1271

1991

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Molecular modeling of renin inhibitor P2 substituents

Advances in experimental medicine and biology, 1991, Vol.306, p.391

1991

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γ-Carbamate butenolide analogues as potent ET A selective endothelin receptor antagonists and prodrugs

Bioorganic & medicinal chemistry letters, 1997-02, Vol.7 (3), p.297-302

1997

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New inhibitors of human renin that contain novel replacement at the P2 site

Journal of medicinal chemistry, 1991, Vol.34 (4), p.1258-1271

1991

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Dexmedetomidine Reduces Shivering during Mild Hypothermia in Waking Subjects

PloS one, 2015-08, Vol.10 (8), p.e0129709

2015

Volltextzugriff (PDF)

Oxidative stress in chronic obstructive pulmonary disease

American journal of respiratory and critical care medicine, 1997-08, Vol.156 (2), p.341-357

1997

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Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome : Time for a reevaluation

Critical care medicine, 2000, Vol.28 (1), p.232-235

2000

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Preventing the Acute Respiratory Distress Syndrome

Preventive medicine, 2012-05, Vol.54, p.S17-S19

2012

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L-ergothioneine reduces nitration of lactoferrin and loss of antibacterial activity associated with nitrosative stress

Biochemistry and biophysics reports, 2023-07, Vol.34, p.101447-101447, Article 101447

2023

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Injury Characteristics and von Willebrand Factor for the Prediction of Acute Respiratory Distress Syndrome in Patients With Burn Injury: Development and Internal Validation

Annals of surgery, 2019-12, Vol.270 (6), p.1186

2019

Volltextzugriff (PDF)

Development of a sandwich ELISA with potential for selective quantification of human lactoferrin protein nitrated through disease or environmental exposure

Analytical and bioanalytical chemistry, 2018-02, Vol.410 (4), p.1389-1396

2018

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Comparison of three cognitive exams in cardiac arrest survivors

Resuscitation, 2017-07, Vol.116, p.98-104

2017

Volltextzugriff (PDF)

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Discovery of a Potent and Selective Inhibitor of Cyclin-Dependent Kinase 4/6

Renin inhibitors containing isosteric replacements of the amide bond connecting the P3 and P2 sites

Structure−Activity Relationships in a Series of Orally Active γ-Hydroxy Butenolide Endothelin Antagonists

Butenolide Endothelin Antagonists with Improved Aqueous Solubility

Renin inhibitors containing .alpha.-heteroatom amino acids as P2 residues

Design, synthesis and solution structure of a renin inhibitor Structural constraints from NOE, and homonuclear and heteronuclear coupling constants combined with distance geometry calculations

Renin inhibitors containing esters at the P2-position. Oral activity in a derivative of methyl aminomalonate

Modified di- and tripeptides of the C-terminal portion of oxytocin and vasopressin as possible cognition activation agents

Pyrido[2,3-d]pyrimidin-7-ones as Specific Inhibitors of Cyclin-Dependent Kinase 4

Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors

New inhibitors of human renin that contain novel replacements at the P2 site

Psi [CH2NH] backbone-modified peptides: first unequivocal observation of a C7 structure in a linear peptide

γ-Carbamate butenolide analogues as potent ETA selective endothelin receptor antagonists and prodrugs

New inhibitors of human renin that contain novel replacements at the P sub(2) site

Molecular modeling of renin inhibitor P2 substituents

γ-Carbamate butenolide analogues as potent ET A selective endothelin receptor antagonists and prodrugs

New inhibitors of human renin that contain novel replacement at the P2 site

Dexmedetomidine Reduces Shivering during Mild Hypothermia in Waking Subjects

Oxidative stress in chronic obstructive pulmonary disease

Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome : Time for a reevaluation

Preventing the Acute Respiratory Distress Syndrome

L-ergothioneine reduces nitration of lactoferrin and loss of antibacterial activity associated with nitrosative stress

Injury Characteristics and von Willebrand Factor for the Prediction of Acute Respiratory Distress Syndrome in Patients With Burn Injury: Development and Internal Validation

Development of a sandwich ELISA with potential for selective quantification of human lactoferrin protein nitrated through disease or environmental exposure

Comparison of three cognitive exams in cardiac arrest survivors

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