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The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications

Current cancer drug targets, 2008-05, Vol.8 (3), p.187

2008

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Absence of Glial Fibrillary Acidic Protein and Vimentin Prevents Hypertrophy of Astrocytic Processes and Improves Post-Traumatic Regeneration

The Journal of neuroscience, 2004-05, Vol.24 (21), p.5016-5021

2004

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Pericytes and the Pathogenesis of Diabetic Retinopathy

Diabetes (New York, N.Y.), 2002-10, Vol.51 (10), p.3107-3112

2002

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Chemical Interrogation of FOXO3a Nuclear Translocation Identifies Potent and Selective Inhibitors of Phosphoinositide 3-Kinases

The Journal of biological chemistry, 2009-10, Vol.284 (41), p.28392-28400

2009

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Conditional transgenic expression of PIM1 kinase in prostate induces inflammation-dependent neoplasia

PloS one, 2013-04, Vol.8 (4), p.e60277

2013

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Transcription Profiling of Platelet-Derived Growth Factor-B-Deficient Mouse Embryos Identifies RGS5 as a Novel Marker for Pericytes and Vascular Smooth Muscle Cells

The American journal of pathology, 2003-03, Vol.162 (3), p.721-729

2003

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Mouse models to decipher the PI3K signaling network in human cancer

Current molecular medicine, 2009-06, Vol.9 (5), p.612

2009

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Exploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models

PloS one, 2010-02, Vol.5 (2), p.e9305-e9305

2010

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Correction: Conditional Transgenic Expression of PIM1 Kinase in Prostate Induces Inflammation-Dependent Neoplasia

PloS one, 2013-05, Vol.8 (5)

2013

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Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate

Carcinogenesis (New York), 2007-07, Vol.28 (7), p.1418-1425

2007

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PTEN, more than the AKT pathway

Carcinogenesis (New York), 2007-07, Vol.28 (7), p.1379-1386

2007

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The Expression of Constitutively Active Isotypes of Protein Kinase C to Investigate Preconditioning

The Journal of biological chemistry, 1998-09, Vol.273 (36), p.23072-23079

1998

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Angiopoietin-2 causes pericyte dropout in the normal retina: Evidence for involvement in diabetic retinopathy

Diabetes (New York, N.Y.), 2004-04, Vol.53 (4), p.1104-1110

2004

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Genetic Modeling of PIM Proteins in Cancer: Proviral Tagging and Cooperation with Oncogenes, Tumor Suppressor Genes, and Carcinogens

Frontiers in oncology, 2014-01, Vol.4, p.109

2014

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Activation of Phosphatidylinositol 3-Kinase by Membrane Localization of p110α Predisposes Mammary Glands to Neoplastic Transformation

Cancer research (Chicago, Ill.), 2008-12, Vol.68 (23), p.9643-9653

2008

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Angiopoietin-2 Causes Pericyte Dropout in the Normal Retina

Diabetes (New York, N.Y.), 2004-04, Vol.53 (4), p.1104-1110

2004

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Abstract 4337: Novel potent and selective orally available CDK8/19 kinase inhibitors

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4337-4337

2016

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Genetic modelling of the PTEN/AKT pathway in cancer research

Clinical & translational oncology, 2008-10, Vol.10 (10), p.618-627

2008

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Abstract A275: Co-targeting PIM and PI3K/mTOR pathways with a single molecule: Novel orally available combined PIM/PI3K and PIM/PI3K/mTOR kinase inhibitors

Molecular cancer therapeutics, 2013-11, Vol.12 (11_Supplement), p.A275-A275

2013

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Mice expressing myrAKT1 in the mammary gland develop carcinogen-induced ER-positive mammary tumors that mimic human breast cancer

Carcinogenesis (New York), 2007-03, Vol.28 (3), p.584-594

2007

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The role of genes involved in neuroplasticity and neurogenesis in the observation of a gene-environment interaction (GxE) in schizophrenia

Current molecular medicine, 2009-05, Vol.9 (4), p.506

2009

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Abstract B227: Discovery of 3-aryl-3H-[1,2,3]triazolo[4,5-b]pyridin-5-ylamine compounds as potent, selective and orally bioavailable inhibitors of PIM kinases

Molecular cancer therapeutics, 2011-11, Vol.10 (11_Supplement), p.B227-B227

2011

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Identification of transcripts specific for physiological gene activation by platelet-derived growth factor (PDGF)-B in intact brain tissue

Journal of cellular biochemistry, 2005-07, Vol.95 (4), p.859-867

2005

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Time- and cell type-specific induction of platelet-derived growth factor receptor-β during cerebral ischemia

Brain research. Molecular brain research., 2003-05, Vol.113 (1), p.44-51

2003

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Cooperation between Cdk4 and p27 super(kip1) in Tumor Development: A Preclinical Model to Evaluate Cell Cycle Inhibitors with Therapeutic Activity

Cancer research (Chicago, Ill.), 2005-05, Vol.65 (9), p.3846-3852

2005

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The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications

Absence of Glial Fibrillary Acidic Protein and Vimentin Prevents Hypertrophy of Astrocytic Processes and Improves Post-Traumatic Regeneration

Pericytes and the Pathogenesis of Diabetic Retinopathy

Chemical Interrogation of FOXO3a Nuclear Translocation Identifies Potent and Selective Inhibitors of Phosphoinositide 3-Kinases

Conditional transgenic expression of PIM1 kinase in prostate induces inflammation-dependent neoplasia

Transcription Profiling of Platelet-Derived Growth Factor-B-Deficient Mouse Embryos Identifies RGS5 as a Novel Marker for Pericytes and Vascular Smooth Muscle Cells

Mouse models to decipher the PI3K signaling network in human cancer

Exploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models

Correction: Conditional Transgenic Expression of PIM1 Kinase in Prostate Induces Inflammation-Dependent Neoplasia

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate

PTEN, more than the AKT pathway

The Expression of Constitutively Active Isotypes of Protein Kinase C to Investigate Preconditioning

Angiopoietin-2 causes pericyte dropout in the normal retina: Evidence for involvement in diabetic retinopathy

Genetic Modeling of PIM Proteins in Cancer: Proviral Tagging and Cooperation with Oncogenes, Tumor Suppressor Genes, and Carcinogens

Activation of Phosphatidylinositol 3-Kinase by Membrane Localization of p110α Predisposes Mammary Glands to Neoplastic Transformation

Angiopoietin-2 Causes Pericyte Dropout in the Normal Retina

Abstract 4337: Novel potent and selective orally available CDK8/19 kinase inhibitors

Genetic modelling of the PTEN/AKT pathway in cancer research

Abstract A275: Co-targeting PIM and PI3K/mTOR pathways with a single molecule: Novel orally available combined PIM/PI3K and PIM/PI3K/mTOR kinase inhibitors

Mice expressing myrAKT1 in the mammary gland develop carcinogen-induced ER-positive mammary tumors that mimic human breast cancer

The role of genes involved in neuroplasticity and neurogenesis in the observation of a gene-environment interaction (GxE) in schizophrenia

Abstract B227: Discovery of 3-aryl-3H-[1,2,3]triazolo[4,5-b]pyridin-5-ylamine compounds as potent, selective and orally bioavailable inhibitors of PIM kinases

Identification of transcripts specific for physiological gene activation by platelet-derived growth factor (PDGF)-B in intact brain tissue

Time- and cell type-specific induction of platelet-derived growth factor receptor-β during cerebral ischemia

Cooperation between Cdk4 and p27 super(kip1) in Tumor Development: A Preclinical Model to Evaluate Cell Cycle Inhibitors with Therapeutic Activity

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