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Phospholipase C-mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane

The Journal of cell biology, 2009-02, Vol.184 (3), p.451-462

2009

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First FDA Approval of Dual Anti-HER2 Regimen: Pertuzumab in Combination with Trastuzumab and Docetaxel for HER2-Positive Metastatic Breast Cancer

Clinical cancer research, 2013-09, Vol.19 (18), p.4911-4916

2013

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Considerations for the development of therapeutic monoclonal antibodies

Current opinion in immunology, 2008-08, Vol.20 (4), p.493-499

2008

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Intramolecular Regulation of Phospholipase C-γ1 by Its C-Terminal Src Homology 2 Domain

Molecular and Cellular Biology, 2007-02, Vol.27 (3), p.854-863

2007

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Patient-Centric Quality Standards

Journal of pharmaceutical sciences, 2024-04, Vol.113 (4), p.837-855

2024

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Strategies for Setting Patient-Centric Commercial Specifications for Biotherapeutic Products

Journal of pharmaceutical sciences, 2021-02, Vol.110 (2), p.771-784

2021

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Activation-Induced Ubiquitination of the T Cell Antigen Receptor

Science (American Association for the Advancement of Science), 1992-08, Vol.257 (5071), p.795-797

1992

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Expectations for Phase-Appropriate Drug Substance and Drug Product Specifications for Early-Stage Protein Therapeutics

Journal of pharmaceutical sciences, 2019-04, Vol.108 (4), p.1442-1452

2019

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Membrane Raft-Dependent Regulation of Phospholipase Cγ-1 Activation in T Lymphocytes

Molecular and Cellular Biology, 2001-10, Vol.21 (20), p.6939-6950

2001

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Understanding Quality Paradigm Shifts in the Evolving Pharmaceutical Landscape: Perspectives from the USP Quality Advisory Group

The AAPS journal, 2021-10, Vol.23 (6), p.112-112, Article 112

2021

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A dynamic constitutive and inducible binding of c-Cbl by PLCγ1 SH3 and SH2 domains (negatively) regulates antigen receptor-induced PLCγ1 activation in lymphocytes

Experimental cell research, 2003-09, Vol.289 (1), p.184-194

2003

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PDA Biosimilars Workshop Report (September 27-28, 2018)-Getting It Right the First Time for Biosimilar Marketing Applications

PDA journal of pharmaceutical science and technology, 2019-07, Vol.73 (4), p.401

2019

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Functional Independence and Interdependence of the Src Homology Domains of Phospholipase C-γ1 in B-Cell Receptor Signal Transduction

Molecular and Cellular Biology, 1999-11, Vol.19 (11), p.7388-7398

1999

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A New Tyrosine Phosphorylation Site in PLCγ1: The Role of Tyrosine 775 in Immune Receptor Signaling

The Journal of immunology (1950), 2005-05, Vol.174 (10), p.6233-6237

2005

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Phosphorylation and O-linked glycosylation of Elf-1 leads to its translocation to the nucleus and binding to the promoter of the TCR zeta-chain

The Journal of immunology (1950), 2002-03, Vol.168 (6), p.2865-2871

2002

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Phospholipase C–mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane

The Journal of experimental medicine, 2009-02, Vol.206 (2), p.i4-i4

2009

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A new tyrosine phosphorylation site in PLC gamma 1: the role of tyrosine 775 in immune receptor signaling

The Journal of immunology (1950), 2005-05, Vol.174 (10), p.6233-6237

2005

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Intramolecular regulation of phospholipase C-gamma1 by its C-terminal Src homology 2 domain

Molecular and cellular biology, 2007-02, Vol.27 (3), p.854-863

2007

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In vivo induction of anergy in peripheral Vβ8+ T cells by staphylococcal enterotoxin B

The Journal of experimental medicine, 1990-10, Vol.172 (4), p.1091-1100

1990

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Cbl-mediated regulation of T cell receptor-induced AP1 activation. Implications for activation via the Ras signaling pathway

The Journal of biological chemistry, 1997-12, Vol.272 (49), p.30806-30811

1997

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Cbl-mediated Regulation of T Cell Receptor-induced AP1 Activation

The Journal of biological chemistry, 1997-12, Vol.272 (49), p.30806-30811

1997

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The Amino-Terminal Src Homology 2 Domain of Phospholipase Cγ1 Is Essential for TCR-Induced Tyrosine Phosphorylation of Phospholipase Cγ1

The Journal of immunology (1950), 1998-02, Vol.160 (3), p.1059-1066

1998

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Elf-1 regulates basal expression from the T cell antigen receptor zeta-chain gene promoter

The Journal of immunology (1950), 1998-03, Vol.160 (6), p.2794-2801

1998

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A dynamic constitutive and inducible binding of c-Cbl by PLCgamma1 SH3 and SH2 domains (negatively) regulates antigen receptor-induced PLCgamma1 activation in lymphocytes

Experimental cell research, 2003-09, Vol.289 (1), p.184-194

2003

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70Z 3 Cbl induces PLC 1 activation in T lymphocytes via an alternate Lat- and Slp-76-independent signaling mechanism

Oncogene, 2003-04, Vol.22 (16), p.2493-2503

2003

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Phospholipase C-mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane

First FDA Approval of Dual Anti-HER2 Regimen: Pertuzumab in Combination with Trastuzumab and Docetaxel for HER2-Positive Metastatic Breast Cancer

Considerations for the development of therapeutic monoclonal antibodies

Intramolecular Regulation of Phospholipase C-γ1 by Its C-Terminal Src Homology 2 Domain

Patient-Centric Quality Standards

Strategies for Setting Patient-Centric Commercial Specifications for Biotherapeutic Products

Activation-Induced Ubiquitination of the T Cell Antigen Receptor

Expectations for Phase-Appropriate Drug Substance and Drug Product Specifications for Early-Stage Protein Therapeutics

Membrane Raft-Dependent Regulation of Phospholipase Cγ-1 Activation in T Lymphocytes

Understanding Quality Paradigm Shifts in the Evolving Pharmaceutical Landscape: Perspectives from the USP Quality Advisory Group

A dynamic constitutive and inducible binding of c-Cbl by PLCγ1 SH3 and SH2 domains (negatively) regulates antigen receptor-induced PLCγ1 activation in lymphocytes

PDA Biosimilars Workshop Report (September 27-28, 2018)-Getting It Right the First Time for Biosimilar Marketing Applications

Functional Independence and Interdependence of the Src Homology Domains of Phospholipase C-γ1 in B-Cell Receptor Signal Transduction

A New Tyrosine Phosphorylation Site in PLCγ1: The Role of Tyrosine 775 in Immune Receptor Signaling

Phosphorylation and O-linked glycosylation of Elf-1 leads to its translocation to the nucleus and binding to the promoter of the TCR zeta-chain

Phospholipase C–mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane

A new tyrosine phosphorylation site in PLC gamma 1: the role of tyrosine 775 in immune receptor signaling

Intramolecular regulation of phospholipase C-gamma1 by its C-terminal Src homology 2 domain

In vivo induction of anergy in peripheral Vβ8+ T cells by staphylococcal enterotoxin B

Cbl-mediated regulation of T cell receptor-induced AP1 activation. Implications for activation via the Ras signaling pathway

Cbl-mediated Regulation of T Cell Receptor-induced AP1 Activation

The Amino-Terminal Src Homology 2 Domain of Phospholipase Cγ1 Is Essential for TCR-Induced Tyrosine Phosphorylation of Phospholipase Cγ1

Elf-1 regulates basal expression from the T cell antigen receptor zeta-chain gene promoter

A dynamic constitutive and inducible binding of c-Cbl by PLCgamma1 SH3 and SH2 domains (negatively) regulates antigen receptor-induced PLCgamma1 activation in lymphocytes

70Z 3 Cbl induces PLC 1 activation in T lymphocytes via an alternate Lat- and Slp-76-independent signaling mechanism

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