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Lysosomal membrane permeabilization and cathepsin release is a Bax Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes

Cell death and differentiation, 2010-07, Vol.17 (7), p.1167-1178

2010

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Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression

Oncogene, 2014-09, Vol.33 (36), p.4474-4484

2014

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Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis

Oncogene, 2010-03, Vol.29 (11), p.1611-1621

2010

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Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model

Oncogene, 2014-06, Vol.33 (26), p.3392-3400

2014

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STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett’s adenocarcinomas

Oncogene, 2014-06, Vol.33 (25), p.3256-3266

2014

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Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice

Oncogene, 2011-01, Vol.30 (1), p.54-64

2011

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Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice

Oncogene, 2008-07, Vol.27 (30), p.4191-4199

2008

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Towards Specific Functions of Lysosomal Cysteine Peptidases: Phenotypes of Mice Deficient for Cathepsin B or Cathepsin L

Biological chemistry, 2001-05, Vol.382 (5), p.735-741

2001

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The PI3K regulatory subunits p55α and p50α regulate cell death in vivo

Cell death and differentiation, 2014-09, Vol.21 (9), p.1442-1450

2014

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Dilated Cardiomyopathy in Mice Deficient for the Lysosomal Cysteine Peptidase Cathepsin L

Proceedings of the National Academy of Sciences - PNAS, 2002-04, Vol.99 (9), p.6234-6239

2002

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Specialized roles for cysteine cathepsins in health and disease

The Journal of clinical investigation, 2010-10, Vol.120 (10), p.3421-3431

2010

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Cathepsin proteases promote angiogenic sprouting and laser-induced choroidal neovascularisation in mice

Experimental eye research, 2013-10, Vol.115, p.73-78

2013

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Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome

The Journal of biological chemistry, 1995-02, Vol.270 (5), p.2344-2351

1995

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Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice

The FASEB journal, 2006-06, Vol.20 (8), p.1266-1268

2006

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Cathepsin L is involved in cathepsin D processing and regulation of apoptosis in A549 human lung epithelial cells

Biological chemistry, 2004-07, Vol.385 (7), p.665-670

2004

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Calvarial osteoclasts express a higher level of tartrate-resistant acid phosphatase than long bone osteoclasts and activation does not depend on cathepsin K or L activity

Calcified tissue international, 2006-10, Vol.79 (4), p.245-254

2006

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Cathepsin L and Arg/Lys aminopeptidase: a distinct prohormone processing pathway for the biosynthesis of peptide neurotransmitters and hormones

Biological chemistry, 2004-06, Vol.385 (6), p.473-480

2004

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Emerging roles of cysteine cathepsins in disease and their potential as drug targets

Current pharmaceutical design, 2007-02, Vol.13 (4), p.387-403

2007

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Distinct roles for cysteine cathepsin genes in multistage tumorigenesis

Genes & development, 2006-03, Vol.20 (5), p.543-556

2006

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Toward Computer-Based Cleavage Site Prediction of Cysteine Endopeptidases

Biological chemistry, 2003-06, Vol.384 (6), p.899-909

2003

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Cathepsin protease activity modulates amyloid load in extracerebral amyloidosis

The Journal of pathology, 2006-12, Vol.210 (4), p.478-487

2006

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Combinatorial Omics Analysis Reveals Perturbed Lysosomal Homeostasis in Collagen VII-deficient Keratinocytes

Molecular & cellular proteomics, 2018-04, Vol.17 (4), p.565-579

2018

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Cathepsin C is a tissue-specific regulator of squamous carcinogenesis

Genes & development, 2013-10, Vol.27 (19), p.2086-2098

2013

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Degradation of hypochlorite-damaged glucose-6-phosphate dehydrogenase by the 20S proteasome

Free radical biology & medicine, 1999-09, Vol.27 (5), p.487-492

1999

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Lysosomal membrane permeabilization and cathepsin release is a Bax Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes

Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression

Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis

Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model

STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett’s adenocarcinomas

Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice

Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice

Towards Specific Functions of Lysosomal Cysteine Peptidases: Phenotypes of Mice Deficient for Cathepsin B or Cathepsin L

The PI3K regulatory subunits p55α and p50α regulate cell death in vivo

Dilated Cardiomyopathy in Mice Deficient for the Lysosomal Cysteine Peptidase Cathepsin L

Specialized roles for cysteine cathepsins in health and disease

Cathepsin proteases promote angiogenic sprouting and laser-induced choroidal neovascularisation in mice

Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome

Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice

Cathepsin L is involved in cathepsin D processing and regulation of apoptosis in A549 human lung epithelial cells

Calvarial osteoclasts express a higher level of tartrate-resistant acid phosphatase than long bone osteoclasts and activation does not depend on cathepsin K or L activity

Cathepsin L and Arg/Lys aminopeptidase: a distinct prohormone processing pathway for the biosynthesis of peptide neurotransmitters and hormones

Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis

Emerging roles of cysteine cathepsins in disease and their potential as drug targets

Distinct roles for cysteine cathepsin genes in multistage tumorigenesis

Toward Computer-Based Cleavage Site Prediction of Cysteine Endopeptidases

Cathepsin protease activity modulates amyloid load in extracerebral amyloidosis

Combinatorial Omics Analysis Reveals Perturbed Lysosomal Homeostasis in Collagen VII-deficient Keratinocytes

Cathepsin C is a tissue-specific regulator of squamous carcinogenesis

Degradation of hypochlorite-damaged glucose-6-phosphate dehydrogenase by the 20S proteasome

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