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Properties of mutant contractile proteins that cause hypertrophic cardiomyopathy

Cardiovascular research, 1999-10, Vol.44 (1), p.20-36

1999

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A Mutant Tropomyosin That Causes Hypertrophic Cardiomyopathy Is Expressed In Vivo and Associated With an Increased Calcium Sensitivity

Circulation research, 1998-01, Vol.82 (1), p.106-115

1998

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The molecular anatomy of caldesmon

Biochemical journal, 1991-10, Vol.279 (1), p.1-16

1991

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The essential role of tropomyosin in cooperative regulation of smooth muscle thin filament activity by caldesmon

The Journal of biological chemistry, 1993-06, Vol.268 (17), p.12317-12320

1993

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Binding and regulatory properties of expressed functional domains of chicken gizzard smooth muscle caldesmon

The Journal of biological chemistry, 1993-05, Vol.268 (15), p.10969-10976

1993

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The Effect of the Arg91Gly and Glu139del Mutations in β-Tropomyosin Associated with Congenital Myopathy of Human Skeletal Muscles on Actin–Myosin Interaction

Cell and tissue biology, 2018-05, Vol.12 (3), p.238-246

2018

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Modulation of Thin Filament Activation by Breakdown or Isoform Switching of Thin Filament Proteins: Physiological and Pathological Implications

Circulation research, 2003-12, Vol.93 (12), p.1170-1178

2003

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Altered Regulatory Properties of Human Cardiac Troponin I Mutants That Cause Hypertrophic Cardiomyopathy

The Journal of biological chemistry, 2000-07, Vol.275 (29), p.22069-22074

2000

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Synchronous in situ ATPase activity, mechanics, and Ca2+ sensitivity of human and porcine myocardium

Biophysical journal, 2009-11, Vol.97 (9), p.2503-2512

2009

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Inhibition of actin-tropomyosin activation of myosin MgATPase activity by the smooth muscle regulatory protein caldesmon

The Journal of biological chemistry, 1992-08, Vol.267 (24), p.16796-16800

1992

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Effects of troponin C isoform on the action of the cardiotonic agent EMD 57033

Biochemical journal, 2005-06, Vol.388 (Pt 3), p.905-912

2005

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Identification of functioning regulatory sites and a new myosin binding site in the C-terminal 288 amino acids of caldesmon expressed from a human clone

Journal of muscle research and cell motility, 1993-08, Vol.14 (4), p.385-391

1993

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Reversal of caldesmon function by anti-caldesmon antibodies confirms its role in the calcium regulation of vascular smooth muscle thin filaments

Biochemical and biophysical research communications, 1988-08, Vol.155 (1), p.197-202

1988

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The functional properties of full length and mutant chicken gizzard smooth muscle caldesmon expressed in Escherichia coli

FEBS letters, 1990-09, Vol.270 (1), p.53-56

1990

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Effects of Two Hypertrophic Cardiomyopathy Mutations in α-Tropomyosin, Asp175Asn and Glu180Gly, on Ca2+Regulation of Thin Filament Motility

Biochemical and biophysical research communications, 1997-07, Vol.236 (3), p.760-764

1997

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DCM troponin C mutant Gly159Asp blunts the response to troponin phosphorylation

Biochemical and biophysical research communications, 2007-08, Vol.360 (1), p.27-32

2007

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016 Distinctive role for protein phosphatases and protein kinases in the regulation of myocardial contraction by the neuronal nitric oxide synthase

Heart (British Cardiac Society), 2010-06, Vol.96 (Suppl 1), p.A11-A12

2010

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Dilated cardiomyopathy mutations in α-tropomyosin inhibit its movement during the ATPase cycle

Biochemical and biophysical research communications, 2009-04, Vol.381 (3), p.403-406

2009

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Synchronous In Situ ATPase Activity, Mechanics, and Ca super(2+) Sensitivity of Human and Porcine Myocardium

Biophysical journal, 2009-11, Vol.97 (9), p.2503-2512

2009

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Abnormal tropomyosin function in ATPase cycle in hypertrophic and dilated cardiomyopathies

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2013-01, Vol.99 (1), p.73

2013

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The functional effects of mutations Thr673→Asp and Ser702→Asp at the pro-directed kinase phosphorylation sites in the C-terminus of chicken gizzard caldesmon

FEBS letters, 1993-07, Vol.327 (1), p.85-89

1993

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Mutations in fast skeletal troponin I, troponin T, and ss-tropomyosin that cause distal arthrogryposis all increase contractile function

The FASEB journal, 2007-03, Vol.21 (3), p.896-905

2007

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Effect of mutation Arg9lGly on the thermal stability of beta-tropomyosin

Biofizika, 2008-11, Vol.53 (6), p.917

2008

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Phosphorylation of aorta caldesmon by endogeneous proteolytic fragments of protein kinase C

Journal of muscle research and cell motility, 1994-02, Vol.15 (1), p.37-48

1994

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Identification of casein kinase II as a major endogeneous caldesmon kinase in sheep aorta smooth muscle

FEBS letters, 1993-11, Vol.334 (1), p.18-22

1993

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Properties of mutant contractile proteins that cause hypertrophic cardiomyopathy

A Mutant Tropomyosin That Causes Hypertrophic Cardiomyopathy Is Expressed In Vivo and Associated With an Increased Calcium Sensitivity

The molecular anatomy of caldesmon

The essential role of tropomyosin in cooperative regulation of smooth muscle thin filament activity by caldesmon

Binding and regulatory properties of expressed functional domains of chicken gizzard smooth muscle caldesmon

The Effect of the Arg91Gly and Glu139del Mutations in β-Tropomyosin Associated with Congenital Myopathy of Human Skeletal Muscles on Actin–Myosin Interaction

Modulation of Thin Filament Activation by Breakdown or Isoform Switching of Thin Filament Proteins: Physiological and Pathological Implications

Altered Regulatory Properties of Human Cardiac Troponin I Mutants That Cause Hypertrophic Cardiomyopathy

Synchronous in situ ATPase activity, mechanics, and Ca2+ sensitivity of human and porcine myocardium

Inhibition of actin-tropomyosin activation of myosin MgATPase activity by the smooth muscle regulatory protein caldesmon

Effects of troponin C isoform on the action of the cardiotonic agent EMD 57033

Identification of functioning regulatory sites and a new myosin binding site in the C-terminal 288 amino acids of caldesmon expressed from a human clone

Reversal of caldesmon function by anti-caldesmon antibodies confirms its role in the calcium regulation of vascular smooth muscle thin filaments

The functional properties of full length and mutant chicken gizzard smooth muscle caldesmon expressed in Escherichia coli

Effects of Two Hypertrophic Cardiomyopathy Mutations in α-Tropomyosin, Asp175Asn and Glu180Gly, on Ca2+Regulation of Thin Filament Motility

DCM troponin C mutant Gly159Asp blunts the response to troponin phosphorylation

016 Distinctive role for protein phosphatases and protein kinases in the regulation of myocardial contraction by the neuronal nitric oxide synthase

Dilated cardiomyopathy mutations in α-tropomyosin inhibit its movement during the ATPase cycle

Synchronous In Situ ATPase Activity, Mechanics, and Ca super(2+) Sensitivity of Human and Porcine Myocardium

Abnormal tropomyosin function in ATPase cycle in hypertrophic and dilated cardiomyopathies

The functional effects of mutations Thr673→Asp and Ser702→Asp at the pro-directed kinase phosphorylation sites in the C-terminus of chicken gizzard caldesmon

Mutations in fast skeletal troponin I, troponin T, and ss-tropomyosin that cause distal arthrogryposis all increase contractile function

Effect of mutation Arg9lGly on the thermal stability of beta-tropomyosin

Phosphorylation of aorta caldesmon by endogeneous proteolytic fragments of protein kinase C

Identification of casein kinase II as a major endogeneous caldesmon kinase in sheep aorta smooth muscle

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