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Genotoxicity evaluation of the naturally-derived food colorant, gardenia blue, and its precursor, genipin

Food and chemical toxicology, 2018-08, Vol.118, p.695-708

2018

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Genotoxicity evaluation of the flavonoid, myricitrin, and its aglycone, myricetin

Food and chemical toxicology, 2015-09, Vol.83, p.283-292

2015

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Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water

Critical reviews in toxicology, 2015-01, Vol.45 (1), p.1-43

2015

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Impact of Genomics Platform and Statistical Filtering on Transcriptional Benchmark Doses (BMD) and Multiple Approaches for Selection of Chemical Point of Departure (PoD)

PloS one, 2015-08, Vol.10 (8), p.e0136764

2015

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Comprehensive evaluation of the flavonol anti-oxidants, alpha-glycosyl isoquercitrin and isoquercitrin, for genotoxic potential

Food and chemical toxicology, 2018-03, Vol.113, p.218-227

2018

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Flow cytometric micronucleus assay and TGx-DDI transcriptomic biomarker analysis of ten genotoxic and non-genotoxic chemicals in human HepaRG™ cells

Genes and environment, 2020-02, Vol.42 (1), p.5-14, Article 5

2020

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Mining the Archives: A Cross-Platform Analysis of Gene Expression Profiles in Archival Formalin-Fixed Paraffin-Embedded Tissues

Toxicological sciences, 2015-12, Vol.148 (2), p.460-472

2015

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Dose-response assessment of four genotoxic chemicals in a combined mouse and rat micronucleus (MN) and Comet assay protocol

The Journal of Toxicological Sciences, 2010, Vol.35(2), pp.149-162

2010

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Impact of Acrylamide on Calcium Signaling and Cytoskeletal Filaments in Testes From F344 Rat

International journal of toxicology, 2017-03, Vol.36 (2), p.124-132

2017

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Transcriptional profiling of male F344 rats suggests the involvement of calcium signaling in the mode of action of acrylamide-induced thyroid cancer

Food and chemical toxicology, 2017-09, Vol.107 (Pt A), p.186-200

2017

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Application of the TGx-28.65 transcriptomic biomarker to classify genotoxic and non-genotoxic chemicals in human TK6 cells in the presence of rat liver S9

Environmental and molecular mutagenesis, 2016-05, Vol.57 (4), p.243-260

2016

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A Modern Genotoxicity Testing Paradigm: Integration of the High-Throughput CometChip® and the TGx-DDI Transcriptomic Biomarker in Human HepaRG™ Cell Cultures

Frontiers in public health, 2021-08, Vol.9, p.694834-694834

2021

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Biomarkers of exposure and effect in human lymphoblastoid TK6 cells following [13C2]-acetaldehyde exposure

Toxicological sciences, 2013-05, Vol.133 (1), p.1-12

2013

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Comet assay evaluation of six chemicals of known genotoxic potential in rats

Mutation research. Genetic toxicology and environmental mutagenesis, 2015-07, Vol.786-788, p.172-181

2015

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Relative potency for altered humoral immunity induced by polybrominated and polychlorinated dioxins/furans in female B6C3F1/N mice

Toxicological sciences, 2014-06, Vol.139 (2), p.488-500

2014

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Investigation of the Low-Dose Response in the In Vivo Induction of Micronuclei and Adducts by Acrylamide

Toxicological sciences, 2009-01, Vol.107 (1), p.247-257

2009

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Comparison of Comet assay dose-response for ethyl methanesulfonate using freshly prepared versus cryopreserved tissues

Environmental and molecular mutagenesis, 2012-03, Vol.53 (2), p.101-113

2012

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Evaluation of the genotoxicity of the food additive, gum ghatti

Food and chemical toxicology, 2012-03, Vol.50 (3-4), p.854-860

2012

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Genotoxicity assessment in HepaRG™ cells as a new approach methodology follow up to a positive response in the human TK6 cell micronucleus assay: Naphthalene case study

Environmental and molecular mutagenesis, 2023-10, Vol.64 (8-9), p.458-465

2023

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Gene expression analysis of livers from female B6C3F1 mice exposed to carcinogenic and non-carcinogenic doses of furan, with or without bromodeoxyuridine (BrdU) treatment

Genomics data, 2014-12, Vol.2 (C), p.117-122

2014

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A predictive toxicogenomics signature to classify genotoxic versus non-genotoxic chemicals in human TK6 cells

Data in brief, 2015-12, Vol.5 (C), p.77-83

2015

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Increasing confidence in new approach methodologies for inhalation risk assessment with multiple end point assays using 5-day repeated exposure to 1,3-dichloropropene

Toxicology (Amsterdam), 2023-11, Vol.499, p.153642-153642, Article 153642

2023

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Sensitive CometChip assay for screening potentially carcinogenic DNA adducts by trapping DNA repair intermediates

Nucleic acids research, 2020-02, Vol.48 (3), p.e13-e13

2020

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Fifteen day repeat air: liquid Interface air-only exposures can cause respiratory epithelium injury in MucilAir ™ nasal respiratory epithelial cells that parallels chemically induced cytotoxicity

Toxicology mechanisms and methods, 2024-07, p.1-7

2024

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Exposure of Hematopoietic Stem Cells to Benzene or 1,4‐Benzoquinone Induces Gender‐Specific Gene Expression

Stem cells (Dayton, Ohio), 2004-09, Vol.22 (5), p.750-758

2004

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Genotoxicity evaluation of the naturally-derived food colorant, gardenia blue, and its precursor, genipin

Genotoxicity evaluation of the flavonoid, myricitrin, and its aglycone, myricetin

Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water

Impact of Genomics Platform and Statistical Filtering on Transcriptional Benchmark Doses (BMD) and Multiple Approaches for Selection of Chemical Point of Departure (PoD)

Comprehensive evaluation of the flavonol anti-oxidants, alpha-glycosyl isoquercitrin and isoquercitrin, for genotoxic potential

Flow cytometric micronucleus assay and TGx-DDI transcriptomic biomarker analysis of ten genotoxic and non-genotoxic chemicals in human HepaRG™ cells

Mining the Archives: A Cross-Platform Analysis of Gene Expression Profiles in Archival Formalin-Fixed Paraffin-Embedded Tissues

Dose-response assessment of four genotoxic chemicals in a combined mouse and rat micronucleus (MN) and Comet assay protocol

Impact of Acrylamide on Calcium Signaling and Cytoskeletal Filaments in Testes From F344 Rat

Transcriptional profiling of male F344 rats suggests the involvement of calcium signaling in the mode of action of acrylamide-induced thyroid cancer

Application of the TGx-28.65 transcriptomic biomarker to classify genotoxic and non-genotoxic chemicals in human TK6 cells in the presence of rat liver S9

A Modern Genotoxicity Testing Paradigm: Integration of the High-Throughput CometChip® and the TGx-DDI Transcriptomic Biomarker in Human HepaRG™ Cell Cultures

Biomarkers of exposure and effect in human lymphoblastoid TK6 cells following [13C2]-acetaldehyde exposure

Comet assay evaluation of six chemicals of known genotoxic potential in rats

Relative potency for altered humoral immunity induced by polybrominated and polychlorinated dioxins/furans in female B6C3F1/N mice

Investigation of the Low-Dose Response in the In Vivo Induction of Micronuclei and Adducts by Acrylamide

Comparison of Comet assay dose-response for ethyl methanesulfonate using freshly prepared versus cryopreserved tissues

Evaluation of the genotoxicity of the food additive, gum ghatti

Genotoxicity assessment in HepaRG™ cells as a new approach methodology follow up to a positive response in the human TK6 cell micronucleus assay: Naphthalene case study

Gene expression analysis of livers from female B6C3F1 mice exposed to carcinogenic and non-carcinogenic doses of furan, with or without bromodeoxyuridine (BrdU) treatment

A predictive toxicogenomics signature to classify genotoxic versus non-genotoxic chemicals in human TK6 cells

Increasing confidence in new approach methodologies for inhalation risk assessment with multiple end point assays using 5-day repeated exposure to 1,3-dichloropropene

Sensitive CometChip assay for screening potentially carcinogenic DNA adducts by trapping DNA repair intermediates

Fifteen day repeat air: liquid Interface air-only exposures can cause respiratory epithelium injury in MucilAir ™ nasal respiratory epithelial cells that parallels chemically induced cytotoxicity

Exposure of Hematopoietic Stem Cells to Benzene or 1,4‐Benzoquinone Induces Gender‐Specific Gene Expression

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