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Cardiac protein phosphorylation : functional and pathophysiological correlates

Cardiovascular research, 1998-06, Vol.38 (3), p.559-588

RAPUNDALO, S. T

1998

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Rational Design, Synthesis, and Biological Activity of Benzoxazinones as Novel Factor Xa Inhibitors

Journal of medicinal chemistry, 2000-11, Vol.43 (22), p.4063-4070

2000

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Inotropic Responses to Isoproterenol and Phosphodiesterase Inhibitors in Intact Guinea Pig Hearts: Comparison of Cyclic AMP Levels and Phosphorylation of Sarcoplasmic Reticulum and Myofibrillar Proteins

Circulation research, 1989-01, Vol.64 (1), p.104-111

1989

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Endothelin and structurally related analogs distinguish between endothelin receptor subtypes

Biochemical and biophysical research communications, 1992-03, Vol.183 (2), p.566-571

1992

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Structural Basis of the Thrombin Selectivity of a Ligand That Contains the Constrained Arginine Mimic (2S)-2-Amino-(3S)-3-(1-carbamimidoyl- piperidin-3-yl)-propanoic Acid at P1

Journal of medicinal chemistry, 2000-02, Vol.43 (3), p.361-368

2000

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Design of a functional hexapeptide antagonist of endothelin

Journal of medicinal chemistry, 1992-08, Vol.35 (17), p.3301-3303

1992

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Structure-activity relationships of C-terminal endothelin hexapeptide antagonists

Journal of medicinal chemistry, 1993-09, Vol.36 (18), p.2585-2594

1993

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Effects of a factor Xa inhibitor, DX-9065a, in a novel rabbit model of venous thrombosis

Basic research in cardiology, 1999-02, Vol.94 (1), p.15-22

1999

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Application of Proteomics to the Study of Cardiovascular Biology

Trends in Cardiovascular Medicine, 2001-02, Vol.11 (2), p.66-75

2001

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The design of potent and selective inhibitors of thrombin utilizing a piperazinedione template: Part 1

Bioorganic & medicinal chemistry letters, 1999-09, Vol.9 (17), p.2497-2502

1999

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Potent and selective bicyclic lactam inhibitors of thrombin: Part 2: P1 Modifications

Bioorganic & medicinal chemistry letters, 1998-12, Vol.8 (23), p.3409-3414

1998

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Evidence for a functional tissue renin-angiotensin system in the rat mesenteric vasculature and its involvement in regulating blood pressure

The Journal of pharmacology and experimental therapeutics, 1991-02, Vol.256 (2), p.568

1991

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The design of potent and selective inhibitors of thrombin utilizing a piperazinedione template: Part 2

Bioorganic & medicinal chemistry letters, 1999-09, Vol.9 (17), p.2503-2508

1999

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Cyclic AMP-dependent and cyclic AMP-independent actions of a novel cardiotonic agent, OPC-8212

Naunyn-Schmiedeberg's archives of pharmacology, 1988-12, Vol.338 (6), p.692-698

1988

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Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors

Journal of medicinal chemistry, 1992-07, Vol.35 (14), p.2562-2572

1992

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An efficient synthesis of 2-(3-(4-amidinophenylcarbamoyl)naphthalen-2-yl)-5-((2,2-methylpropyl)carbamoyl)benzoic acid: a factor VIIa inhibitor discovered by the Ono Pharmaceutical Company

Tetrahedron letters, 2000, Vol.41 (32), p.6041-6044

2000

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Structure-Activity Studies of the C-Terminal Region of the Endothelins and the Sarafotoxins

Journal of cardiovascular pharmacology, 1991, Vol.17 Suppl 7, p.S59-61

1991

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Cardiac sarcoplasmic reticulum and sarcolemmal proteins separated by two-dimensional electrophoresis: Surfactant effects on membrane solubilization

Electrophoresis, 2000-05, Vol.21 (9), p.1685-1693

2000

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Importance of secondary structure for endothelin binding and functional activity

Biochemical and biophysical research communications, 1992-03, Vol.183 (2), p.572-576

1992

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Renin inhibitors containing .alpha.-heteroatom amino acids as P2 residues

Journal of medicinal chemistry, 1992-03, Vol.35 (6), p.1032-1042

1992

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Myocardial actions of milrinone: characterization of its mechanism of action

Circulation (New York, N.Y.), 1986-03, Vol.73 (3 Pt 2), p.III134-III144

1986

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Potent and selective bicyclic lactam inhibitors of thrombin: Part 3: P1′ modifications

Bioorganic & medicinal chemistry letters, 1999-03, Vol.9 (6), p.835-840

1999

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Phosphorylation of phospholipids in isolated guinea pig hearts stimulated with isoprenaline

Biochemical journal, 1988-04, Vol.251 (1), p.189-194

1988

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Monocyclic Endothelins: Examination of the Importance of the Individual Disulfide Rings

Journal of cardiovascular pharmacology, 1991, Vol.17 Suppl 7, p.S62-64

1991

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Design, Synthesis, and Biological Activity of Potent and Selective Inhibitors of Blood Coagulation Factor Xa

Journal of medicinal chemistry, 2004-07, Vol.47 (16), p.4089-4099

2004

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Cardiac protein phosphorylation : functional and pathophysiological correlates

Rational Design, Synthesis, and Biological Activity of Benzoxazinones as Novel Factor Xa Inhibitors

Inotropic Responses to Isoproterenol and Phosphodiesterase Inhibitors in Intact Guinea Pig Hearts: Comparison of Cyclic AMP Levels and Phosphorylation of Sarcoplasmic Reticulum and Myofibrillar Proteins

Endothelin and structurally related analogs distinguish between endothelin receptor subtypes

Structural Basis of the Thrombin Selectivity of a Ligand That Contains the Constrained Arginine Mimic (2S)-2-Amino-(3S)-3-(1-carbamimidoyl- piperidin-3-yl)-propanoic Acid at P1

Design of a functional hexapeptide antagonist of endothelin

Structure-activity relationships of C-terminal endothelin hexapeptide antagonists

Effects of a factor Xa inhibitor, DX-9065a, in a novel rabbit model of venous thrombosis

Application of Proteomics to the Study of Cardiovascular Biology

The design of potent and selective inhibitors of thrombin utilizing a piperazinedione template: Part 1

Potent and selective bicyclic lactam inhibitors of thrombin: Part 2: P1 Modifications

Evidence for a functional tissue renin-angiotensin system in the rat mesenteric vasculature and its involvement in regulating blood pressure

The design of potent and selective inhibitors of thrombin utilizing a piperazinedione template: Part 2

Cyclic AMP-dependent and cyclic AMP-independent actions of a novel cardiotonic agent, OPC-8212

Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors

An efficient synthesis of 2-(3-(4-amidinophenylcarbamoyl)naphthalen-2-yl)-5-((2,2-methylpropyl)carbamoyl)benzoic acid: a factor VIIa inhibitor discovered by the Ono Pharmaceutical Company

Structure-Activity Studies of the C-Terminal Region of the Endothelins and the Sarafotoxins

Cardiac sarcoplasmic reticulum and sarcolemmal proteins separated by two-dimensional electrophoresis: Surfactant effects on membrane solubilization

Importance of secondary structure for endothelin binding and functional activity

Renin inhibitors containing .alpha.-heteroatom amino acids as P2 residues

Myocardial actions of milrinone: characterization of its mechanism of action

Potent and selective bicyclic lactam inhibitors of thrombin: Part 3: P1′ modifications

Phosphorylation of phospholipids in isolated guinea pig hearts stimulated with isoprenaline

Monocyclic Endothelins: Examination of the Importance of the Individual Disulfide Rings

Design, Synthesis, and Biological Activity of Potent and Selective Inhibitors of Blood Coagulation Factor Xa

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