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Transcription Factors in Cancer Development and Therapy

Cancers, 2020-08, Vol.12 (8), p.2296

2020

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MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3

Oncogene, 2021-10, Vol.40 (43), p.6153-6165

2021

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Involvement of AMP-activated protein kinase and Death Receptor 5 in TRAIL-Berberine-induced apoptosis of cancer cells

Scientific reports, 2018-04, Vol.8 (1), p.5521-11, Article 5521

2018

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Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1

Oncogene, 2019-05, Vol.38 (19), p.3569-3584

2019

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Ets1 mediates sorafenib resistance by regulating mitochondrial ROS pathway in hepatocellular carcinoma

Cell death & disease, 2022-07, Vol.13 (7), p.581-581, Article 581

2022

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Mitogen-Activated Protein Kinase Inhibitors and T-Cell-Dependent Immunotherapy in Cancer

Pharmaceuticals (Basel, Switzerland), 2020-01, Vol.13 (1), p.9

2020

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Correction: Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1

Oncogene, 2020-01, Vol.39 (3), p.722-722

2020

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Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (21), p.8149-8154

2012

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Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8+ T cells

Journal for immunotherapy of cancer, 2020-08, Vol.8 (2), p.e000494

2020

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Tumor-infiltrating CD8+ T cell antitumor efficacy and exhaustion: molecular insights

Drug discovery today, 2021-04, Vol.26 (4), p.951-967

2021

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Negative Regulation of Mixed Lineage Kinase 3 by Protein Kinase B/AKT Leads to Cell Survival

The Journal of biological chemistry, 2003-02, Vol.278 (6), p.3897-3902

2003

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The regulatory function of mixed lineage kinase 3 in tumor and host immunity

Pharmacology & therapeutics (Oxford), 2021-03, Vol.219, p.107704-107704, Article 107704

2021

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TRAF2-MLK3 interaction is essential for TNF-α-induced MLK3 activation

Cell research, 2010-01, Vol.20 (1), p.89-98

2010

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Dysregulation of immune checkpoint proteins in hepatocellular carcinoma: Impact on metabolic reprogramming

Current opinion in pharmacology, 2022-06, Vol.64, p.102232-102232, Article 102232

2022

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Molecular insights into the role of mixed lineage kinase 3 in cancer hallmarks

Biochimica et biophysica acta. Reviews on cancer, 2024-09, Vol.1879 (5), p.189157, Article 189157

2024

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Gastrin-mediated activation of cyclin D1 transcription involves β-catenin and CREB pathways in gastric cancer cells

Oncogene, 2004-04, Vol.23 (20), p.3689-3699

2004

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Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-Troglitazone-induced Apoptosis in Prostate Cancer Cells Involve AMP-activated Protein Kinase

The Journal of biological chemistry, 2015-09, Vol.290 (36), p.21865-21875

2015

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Protease activated receptor-1 regulates mixed lineage kinase-3 to drive triple-negative breast cancer tumorigenesis

Cancer letters, 2024-10, Vol.603, p.217200, Article 217200

2024

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Mixed Lineage Kinase 3 Promotes Dexamethasone-Induced Thymocyte Apoptosis

The Journal of immunology (1950), 2021-05, Vol.206 (1_Supplement), p.64-64.23

2021

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Abstract 103: Expression and regulation of MMP9 and RECK in human oral squamous cell carcinoma progression and invasion

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.103-103

2018

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Abstract 2338: XAV-939, a Wnt/beta-catenin pathway inhibitor, sensitizes liver cancer cells to sorafenib: Implications in sorafenib resistance

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2338-2338

2018

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Molecular Insights of MAP4K4 Signaling in Inflammatory and Malignant Diseases

Cancers, 2023-04, Vol.15 (8), p.2272

2023

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Berberine Represses β -Catenin Translation Involving 4E-BPs in Hepatocellular Carcinoma Cells

Molecular pharmacology, 2021-01, Vol.99 (1), p.1-16

2021

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Abstract 2614: Elucidation of the molecular mechanisms mediating sorafenib-resistance in Hepatocellular carcinoma

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.2614-2614

2020

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Abstract 108: Elucidation of MLK3-induced signaling pathways in hepatocellular carcinoma

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.108-108

2020

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Transcription Factors in Cancer Development and Therapy

MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3

Involvement of AMP-activated protein kinase and Death Receptor 5 in TRAIL-Berberine-induced apoptosis of cancer cells

Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1

Ets1 mediates sorafenib resistance by regulating mitochondrial ROS pathway in hepatocellular carcinoma

Mitogen-Activated Protein Kinase Inhibitors and T-Cell-Dependent Immunotherapy in Cancer

Correction: Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1

Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function

Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8+ T cells

Tumor-infiltrating CD8+ T cell antitumor efficacy and exhaustion: molecular insights

Negative Regulation of Mixed Lineage Kinase 3 by Protein Kinase B/AKT Leads to Cell Survival

The regulatory function of mixed lineage kinase 3 in tumor and host immunity

TRAF2-MLK3 interaction is essential for TNF-α-induced MLK3 activation

Dysregulation of immune checkpoint proteins in hepatocellular carcinoma: Impact on metabolic reprogramming

Molecular insights into the role of mixed lineage kinase 3 in cancer hallmarks

Gastrin-mediated activation of cyclin D1 transcription involves β-catenin and CREB pathways in gastric cancer cells

Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-Troglitazone-induced Apoptosis in Prostate Cancer Cells Involve AMP-activated Protein Kinase

Protease activated receptor-1 regulates mixed lineage kinase-3 to drive triple-negative breast cancer tumorigenesis

Mixed Lineage Kinase 3 Promotes Dexamethasone-Induced Thymocyte Apoptosis

Abstract 103: Expression and regulation of MMP9 and RECK in human oral squamous cell carcinoma progression and invasion

Abstract 2338: XAV-939, a Wnt/beta-catenin pathway inhibitor, sensitizes liver cancer cells to sorafenib: Implications in sorafenib resistance

Molecular Insights of MAP4K4 Signaling in Inflammatory and Malignant Diseases

Berberine Represses β -Catenin Translation Involving 4E-BPs in Hepatocellular Carcinoma Cells

Abstract 2614: Elucidation of the molecular mechanisms mediating sorafenib-resistance in Hepatocellular carcinoma

Abstract 108: Elucidation of MLK3-induced signaling pathways in hepatocellular carcinoma

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