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Immunomodulatory Drugs for the Treatment of B Cell Malignancies

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8572

2021

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Targeting the tumor microenvironment in chronic lymphocytic leukemia

Haematologica (Roma), 2021-09, Vol.106 (9), p.2312-2324

2021

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Interleukin-27 potentiates CD8+ T-cell-mediated antitumor immunity in chronic lymphocytic leukemia

Haematologica (Roma), 2023-11, Vol.108 (11), p.3011-3024

2023

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Follicular Lymphoma Cells Induce Changes in T-Cell Gene Expression and Function: Potential Impact on Survival and Risk of Transformation

Journal of clinical oncology, 2013-07, Vol.31 (21), p.2654-2661

2013

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Understanding the Immune-Stroma Microenvironment in B Cell Malignancies for Effective Immunotherapy

Frontiers in oncology, 2021-03, Vol.11, p.626818-626818

2021

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The immunomodulatory molecule TIGIT is expressed by chronic lymphocytic leukemia cells and contributes to anergy

Haematologica (Roma), 2023-08, Vol.108 (8), p.2101-2115

2023

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Investigator choice of standard therapy versus sequential novel therapy arms in the treatment of relapsed follicular lymphoma (REFRACT): study protocol for a multi-centre, open-label, randomised, phase II platform trial

BMC cancer, 2024-03, Vol.24 (1), p.370-370, Article 370

2024

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Immune checkpoint blockade immunotherapy to activate anti‐tumour T‐cell immunity

British journal of haematology, 2013-08, Vol.162 (3), p.313-325

Ramsay, Alan G.

2013

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Substrate-driven gene expression in Roseburia inulinivorans: Importance of inducible enzymes in the utilization of inulin and starch

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (Supplement 1), p.4672-4679

2011

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A Detailed Analysis of Parameters Supporting the Engraftment and Growth of Chronic Lymphocytic Leukemia Cells in Immune-Deficient Mice

Frontiers in immunology, 2021-03, Vol.12, p.627020-627020

2021

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Immune dysfunction in chronic lymphocytic leukemia: the role for immunotherapy

Current pharmaceutical design, 2012-08, Vol.18 (23), p.3389-3398

2012

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Integrin trafficking and its role in cancer metastasis

Cancer and metastasis reviews, 2007-12, Vol.26 (3-4), p.567-578, Article 567

2007

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Distinct Chemokine Receptor Expression Profiles in De Novo DLBCL, Transformed Follicular Lymphoma, Richter's Trans-Formed DLBCL and Germinal Center B-Cells

International journal of molecular sciences, 2022-07, Vol.23 (14), p.7874

2022

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Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer

Blood, 2012-08, Vol.120 (7), p.1412-1421

2012

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Eμ-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (15), p.6250-6255

2009

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Tumor microenvironment (TME)-driven immune suppression in B cell malignancy

Biochimica et biophysica acta, 2016-03, Vol.1863 (3), p.471-482

2016

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Immune dysfunction in chronic lymphocytic leukemia T cells and lenalidomide as an immunomodulatory drug

Haematologica (Roma), 2009-09, Vol.94 (9), p.1198-1202

2009

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T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production

Blood, 2013-02, Vol.121 (9), p.1612-1621

2013

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Activated Pancreatic Stellate Cells Sequester CD8+ T Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma

Gastroenterology (New York, N.Y. 1943), 2013-11, Vol.145 (5), p.1121-1132

2013

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Chronic lymphocytic leukemia cells induce defective LFA-1–directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide

Blood, 2013-04, Vol.121 (14), p.2704-2714

2013

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Generation of a poor prognostic chronic lymphocytic leukemia-like disease model: PKCα subversion induces up-regulation of PKCβII expression in B lymphocytes

Haematologica (Roma), 2015-04, Vol.100 (4), p.499

2015

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Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity

Immunity (Cambridge, Mass.), 2021-12, Vol.54 (12), p.2825-2841.e10

2021

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How does lenalidomide target the chronic lymphocytic leukemia microenvironment?

Blood, 2014-10, Vol.124 (14), p.2184-2189

2014

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Effects of alternative dietary substrates on competition between human colonic bacteria in an anaerobic fermentor system

Applied and Environmental Microbiology, 2003-02, Vol.69 (2), p.1136-1142

2003

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Immunomodulatory Drugs for the Treatment of B Cell Malignancies

Targeting the tumor microenvironment in chronic lymphocytic leukemia

Interleukin-27 potentiates CD8+ T-cell-mediated antitumor immunity in chronic lymphocytic leukemia

Follicular Lymphoma Cells Induce Changes in T-Cell Gene Expression and Function: Potential Impact on Survival and Risk of Transformation

Understanding the Immune-Stroma Microenvironment in B Cell Malignancies for Effective Immunotherapy

The immunomodulatory molecule TIGIT is expressed by chronic lymphocytic leukemia cells and contributes to anergy

Investigator choice of standard therapy versus sequential novel therapy arms in the treatment of relapsed follicular lymphoma (REFRACT): study protocol for a multi-centre, open-label, randomised, phase II platform trial

Immune checkpoint blockade immunotherapy to activate anti‐tumour T‐cell immunity

Substrate-driven gene expression in Roseburia inulinivorans: Importance of inducible enzymes in the utilization of inulin and starch

A Detailed Analysis of Parameters Supporting the Engraftment and Growth of Chronic Lymphocytic Leukemia Cells in Immune-Deficient Mice

Immune dysfunction in chronic lymphocytic leukemia: the role for immunotherapy

Integrin trafficking and its role in cancer metastasis

Distinct Chemokine Receptor Expression Profiles in De Novo DLBCL, Transformed Follicular Lymphoma, Richter's Trans-Formed DLBCL and Germinal Center B-Cells

Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer

ImmunoCluster provides a computational framework for the nonspecialist to profile high-dimensional cytometry data

Eμ-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction

Tumor microenvironment (TME)-driven immune suppression in B cell malignancy

Immune dysfunction in chronic lymphocytic leukemia T cells and lenalidomide as an immunomodulatory drug

T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production

Activated Pancreatic Stellate Cells Sequester CD8+ T Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma

Chronic lymphocytic leukemia cells induce defective LFA-1–directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide

Generation of a poor prognostic chronic lymphocytic leukemia-like disease model: PKCα subversion induces up-regulation of PKCβII expression in B lymphocytes

Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity

How does lenalidomide target the chronic lymphocytic leukemia microenvironment?

Effects of alternative dietary substrates on competition between human colonic bacteria in an anaerobic fermentor system

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