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N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domain

PloS one, 2014-11, Vol.9 (11), p.e112794-e112794

2014

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A Recently Evolved Novel Trophoblast-Enriched Secreted Form of fms-Like Tyrosine Kinase-1 Variant Is Up-Regulated in Hypoxia and Preeclampsia

The journal of clinical endocrinology and metabolism, 2009-07, Vol.94 (7), p.2524-2530

2009

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Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channel

American journal of physiology. Renal physiology, 2008-05, Vol.294 (5), p.F1157-F1165

2008

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VEGF-A selectively inhibits FLT1 ectodomain shedding independent of receptor activation and receptor endocytosis

American Journal of Physiology: Cell Physiology, 2018-08, Vol.315 (2), p.C214-C224

2018

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Glycosylphosphatidylinositol-Specific Phospholipase D in Nonalcoholic Fatty Liver Disease: A Preliminary Study

The journal of clinical endocrinology and metabolism, 2006-06, Vol.91 (6), p.2279-2285

2006

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Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist

Experimental cell research, 2013-10, Vol.319 (17), p.2578-2587

2013

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Ectodomain cleavage of FLT1 regulates receptor activation and function and is not required for its downstream intracellular cleavage

Experimental cell research, 2016-05, Vol.344 (1), p.103-111

2016

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Nedd4-2 interacts with occludin to inhibit tight junction formation and enhance paracellular conductance in collecting duct epithelia

American Journal of Physiology - Renal Physiology, 2010-08, Vol.299 (2), p.F436-F444

2010

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Glycosylphosphatidylinositol-specific phospholipase D influences triglyceride-rich lipoprotein metabolism

American journal of physiology: endocrinology and metabolism, 2006-03, Vol.290 (3), p.E463-E470

2006

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EGF regulation of proximal tubule cell proliferation and VEGF‐A secretion

Physiological reports, 2017-09, Vol.5 (18), p.e13453-n/a

2017

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A regulated NH2-terminal Sgk1 variant with enhanced function is expressed in the collecting duct

American journal of physiology. Renal physiology, 2012-12, Vol.303 (11), p.F1527-F1533

2012

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Alternate processing of Flt1 transcripts is directed by conserved cis-elements within an intronic region of FLT1 that reciprocally regulates splicing and polyadenylation

Nucleic acids research, 2010-08, Vol.38 (15), p.5130-5140

2010

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Mutating His29, His125, His133 or His158 abolishes glycosylphosphatidylinositol-specific phospholipase D catalytic activity

Biochemical journal, 2005-10, Vol.391 (Pt 2), p.285-289

2005

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Aldosterone regulates a 5ʹ variant sgk1 transcript via a shared hormone response element in the sgk1 5ʹ regulatory region

Physiological reports, 2017-04, Vol.5 (7), p.e13221-n/a

2017

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An evolutionarily conserved N-terminal Sgk1 variant with enhanced stability and improved function

American Journal of Physiology - Renal Physiology, 2008-11, Vol.295 (5), p.F1440-F1448

2008

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Glycosylphosphatidylinositol-specific phospholipase D improves glucose tolerance

Metabolism, clinical and experimental, 2010-10, Vol.59 (10), p.1413-1420

2010

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Adenoviral Vectors Expressing Human Endostatin-Angiostatin and Soluble Tie2: Enhanced Suppression of Tumor Growth and Antiangiogenic Effects in a Prostate Tumor Model

Molecular therapy, 2005-12, Vol.12 (6), p.1091-1100

2005

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Statin therapy reduces serum levels of glycosylphosphatidylinositol-specific phospholipase D

Translational research : the journal of laboratory and clinical medicine, 2007-09, Vol.150 (3), p.153-157

2007

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Effect of glycosylphosphatidylinositol (GPI)-phospholipase D overexpression on GPI metabolism

Biochemical journal, 2004-03, Vol.378 (Pt 2), p.641-648

2004

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Aspirin inhibits expression of sFLT1 from human cytotrophoblasts induced by hypoxia, via cyclo-oxygenase 1

Placenta (Eastbourne), 2015-04, Vol.36 (4), p.446-453

2015

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Glucose and insulin regulate glycosylphosphatidylinositol-specific phospholipase D expression in islet β cells

Metabolism, clinical and experimental, 2001-12, Vol.50 (12), p.1489-1492

2001

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Post‐translational cleavage of Flt1 occurs very close to transmembrane domain releasing extracellular N‐terminal fragment which binds to PlGF

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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A regulated NH 2 -terminal Sgk1 variant with enhanced function is expressed in the collecting duct

American journal of physiology. Renal physiology, 2012-12, Vol.303 (11), p.F1527-F1533

2012

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A regulated NH^sub 2^-terminal Sgk1 variant with enhanced function is expressed in the collecting duct

American journal of physiology. Renal physiology, 2012-12, Vol.303 (11), p.F1527

2012

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VEGFR‐1/FLT‐1 is induced by protein kinase C and its Ectodomain Cleavage is regulated by glycosylation and metalloproteases

The FASEB journal, 2012-04, Vol.26 (S1)

2012

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N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domain

A Recently Evolved Novel Trophoblast-Enriched Secreted Form of fms-Like Tyrosine Kinase-1 Variant Is Up-Regulated in Hypoxia and Preeclampsia

Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channel

VEGF-A selectively inhibits FLT1 ectodomain shedding independent of receptor activation and receptor endocytosis

Glycosylphosphatidylinositol-Specific Phospholipase D in Nonalcoholic Fatty Liver Disease: A Preliminary Study

Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist

Ectodomain cleavage of FLT1 regulates receptor activation and function and is not required for its downstream intracellular cleavage

Nedd4-2 interacts with occludin to inhibit tight junction formation and enhance paracellular conductance in collecting duct epithelia

Glycosylphosphatidylinositol-specific phospholipase D influences triglyceride-rich lipoprotein metabolism

EGF regulation of proximal tubule cell proliferation and VEGF‐A secretion

A regulated NH2-terminal Sgk1 variant with enhanced function is expressed in the collecting duct

Alternate processing of Flt1 transcripts is directed by conserved cis-elements within an intronic region of FLT1 that reciprocally regulates splicing and polyadenylation

Mutating His29, His125, His133 or His158 abolishes glycosylphosphatidylinositol-specific phospholipase D catalytic activity

Aldosterone regulates a 5ʹ variant sgk1 transcript via a shared hormone response element in the sgk1 5ʹ regulatory region

An evolutionarily conserved N-terminal Sgk1 variant with enhanced stability and improved function

Glycosylphosphatidylinositol-specific phospholipase D improves glucose tolerance

Adenoviral Vectors Expressing Human Endostatin-Angiostatin and Soluble Tie2: Enhanced Suppression of Tumor Growth and Antiangiogenic Effects in a Prostate Tumor Model

Statin therapy reduces serum levels of glycosylphosphatidylinositol-specific phospholipase D

Effect of glycosylphosphatidylinositol (GPI)-phospholipase D overexpression on GPI metabolism

Aspirin inhibits expression of sFLT1 from human cytotrophoblasts induced by hypoxia, via cyclo-oxygenase 1

Glucose and insulin regulate glycosylphosphatidylinositol-specific phospholipase D expression in islet β cells

Post‐translational cleavage of Flt1 occurs very close to transmembrane domain releasing extracellular N‐terminal fragment which binds to PlGF

A regulated NH 2 -terminal Sgk1 variant with enhanced function is expressed in the collecting duct

A regulated NH^sub 2^-terminal Sgk1 variant with enhanced function is expressed in the collecting duct

VEGFR‐1/FLT‐1 is induced by protein kinase C and its Ectodomain Cleavage is regulated by glycosylation and metalloproteases

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