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An alignment-independent three-dimensional quantitative structure-activity relationship study on ron receptor tyrosine kinase inhibitors

Journal of bioinformatics and computational biology, 2022-06, Vol.20 (3), p.2250015

2022

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Design and synthesis of close analogs of LCRF-0004, a potent and selective RON receptor tyrosine kinase inhibitor

Bioorganic & medicinal chemistry letters, 2015-06, Vol.25 (12), p.2527-2531

2015

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Design, synthesis and RON receptor tyrosine kinase inhibitory activity of new head groups analogs of LCRF-0004

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (18), p.3810-3815

2015

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Design and synthesis of constrained analogs of LCRF-0004 as potent RON tyrosine kinase inhibitors

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (17), p.3706-3710

2015

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Ligand‐based Discovery of Novel Small Molecule Inhibitors of RON Receptor Tyrosine Kinase

Molecular informatics, 2022-01, Vol.41 (1), p.e2000181-n/a

2022

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When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?

Frontiers in endocrinology (Lausanne), 2019-02, Vol.10, p.89-89

2019

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N-(4-(6,7-Disubstituted-quinolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: A novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors

Bioorganic & medicinal chemistry letters, 2009-12, Vol.19 (23), p.6552-6556

2009

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N-(3-fluoro-4-(2-arylthieno[3,2- b]pyridin-7-yloxy)phenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: A novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors

Bioorganic & medicinal chemistry letters, 2009-03, Vol.19 (5), p.1323-1328

2009

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Identification of potent and selective VEGFR receptor tyrosine kinase inhibitors having new amide isostere headgroups

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.848-852

2010

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Identification of a novel series of potent RON receptor tyrosine kinase inhibitors

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (9), p.2745-2749

2010

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Design and synthesis of 4-[( s-triazin-2-ylamino)methyl]- N-(2-aminophenyl)-benzamides and their analogues as a novel class of histone deacetylase inhibitors

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.1067-1071

2008

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Identification of a Novel Series of Potent TrkA Receptor Tyrosine Kinase Inhibitors

International Journal of Medicinal Chemistry (Online), 2012-01, Vol.2012 (2012), p.1-6

2012

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SAR and biological evaluation of analogues of a small molecule histone deacetylase inhibitor N-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide ( MGCD0103)

Bioorganic & medicinal chemistry letters, 2009-02, Vol.19 (3), p.644-649

2009

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Substituted N-(2-aminophenyl)-benzamides, ( E)- N-(2-aminophenyl)-acrylamides and their analogues: Novel classes of histone deacetylase inhibitors

Bioorganic & medicinal chemistry letters, 2006-08, Vol.16 (15), p.4048-4052

2006

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4-(Heteroarylaminomethyl)- N-(2-aminophenyl)-benzamides and their analogs as a novel class of histone deacetylase inhibitors

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (4), p.1502-1506

2008

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P3.03-021 When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?

Journal of thoracic oncology, 2017-01, Vol.12 (1), p.S1356-S1357

2017

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P3.03-021 When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?: Topic: Mesothelioma Transitional

Journal of thoracic oncology, 2017-01, Vol.12 (1), p.S1356-S1357

2017

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A potential signaling axis between RON kinase receptor and hypoxia‐inducible factor‐1 alpha in pancreatic cancer

Molecular carcinogenesis, 2021-11, Vol.60 (11), p.734-745

2021

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Cover Image, Volume 60, Issue 11

Molecular carcinogenesis, 2021-11, Vol.60 (11), p.i-i

2021

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Lewis acid-catalyzed Mannich type reactions with potassium organotrifluoroborates

Tetrahedron letters, 2004-04, Vol.45 (17), p.3471-3474

2004

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Amphoteric Character of 2-Vinyloxiranes: Synthetic Equivalents of β,γ-Unsaturated Aldehydes and a Vinylogous Enolate

Angewandte Chemie International Edition, 2000-11, Vol.39 (22), p.4079-4082

2000

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N3-Arylmalonamides: A new series of thieno[3,2-b]pyridine based inhibitors of c-Met and VEGFR2 tyrosine kinases

Bioorganic & medicinal chemistry letters, 2009-12, Vol.19 (24), p.6836-6839

2009

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Discovery of N-(2-Aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide (MGCD0103), an Orally Active Histone Deacetylase Inhibitor

Journal of medicinal chemistry, 2008-07, Vol.51 (14), p.4072-4075

2008

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N-(4-(6,7-Disubstituted-quinolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimi-dazolidine-1-carboxamides: A novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (23), p.6552-6556

2009

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Practical synthesis of acetophenones from phenoltriflates

Tetrahedron letters, 2001-01, Vol.42 (2), p.265-266

2001

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An alignment-independent three-dimensional quantitative structure-activity relationship study on ron receptor tyrosine kinase inhibitors

Design and synthesis of close analogs of LCRF-0004, a potent and selective RON receptor tyrosine kinase inhibitor

Design, synthesis and RON receptor tyrosine kinase inhibitory activity of new head groups analogs of LCRF-0004

Design and synthesis of constrained analogs of LCRF-0004 as potent RON tyrosine kinase inhibitors

Ligand‐based Discovery of Novel Small Molecule Inhibitors of RON Receptor Tyrosine Kinase

When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?

N-(4-(6,7-Disubstituted-quinolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: A novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors

N-(3-fluoro-4-(2-arylthieno[3,2- b]pyridin-7-yloxy)phenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: A novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors

Identification of potent and selective VEGFR receptor tyrosine kinase inhibitors having new amide isostere headgroups

Identification of a novel series of potent RON receptor tyrosine kinase inhibitors

Design and synthesis of 4-[( s-triazin-2-ylamino)methyl]- N-(2-aminophenyl)-benzamides and their analogues as a novel class of histone deacetylase inhibitors

Identification of a Novel Series of Potent TrkA Receptor Tyrosine Kinase Inhibitors

SAR and biological evaluation of analogues of a small molecule histone deacetylase inhibitor N-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide ( MGCD0103)

Substituted N-(2-aminophenyl)-benzamides, ( E)- N-(2-aminophenyl)-acrylamides and their analogues: Novel classes of histone deacetylase inhibitors

4-(Heteroarylaminomethyl)- N-(2-aminophenyl)-benzamides and their analogs as a novel class of histone deacetylase inhibitors

P3.03-021 When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?

P3.03-021 When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?: Topic: Mesothelioma Transitional

A potential signaling axis between RON kinase receptor and hypoxia‐inducible factor‐1 alpha in pancreatic cancer

Cover Image, Volume 60, Issue 11

Lewis acid-catalyzed Mannich type reactions with potassium organotrifluoroborates

Amphoteric Character of 2-Vinyloxiranes: Synthetic Equivalents of β,γ-Unsaturated Aldehydes and a Vinylogous Enolate

N3-Arylmalonamides: A new series of thieno[3,2-b]pyridine based inhibitors of c-Met and VEGFR2 tyrosine kinases

Discovery of N-(2-Aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide (MGCD0103), an Orally Active Histone Deacetylase Inhibitor

N-(4-(6,7-Disubstituted-quinolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimi-dazolidine-1-carboxamides: A novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors

Practical synthesis of acetophenones from phenoltriflates

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