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Chemotherapy by slowing glucosphingolipid synthesis

Biochemical pharmacology, 1999-03, Vol.57 (6), p.589-595

RADIN, N. S

1999

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Apoptotic death by ceramide: will the real killer please stand up?

Medical hypotheses, 2001-07, Vol.57 (1), p.96-100

Radin, N.S.

2001

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Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth

Journal of lipid research, 1995-03, Vol.36 (3), p.611-621

1995

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Epithelial glucosphingolipid expression as a determinant of bacterial adherence and cytokine production

Infection and Immunity, 1994-10, Vol.62 (10), p.4404-4410

1994

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Preparation of the active isomer of 1-phenyl-2-decanoylamino-3-morpholino-1-propanol, inhibitor of murine glucocerebroside synthetase

Journal of lipid research, 1987-05, Vol.28 (5), p.565-571

1987

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Treating glucosphingolipid disorders by chemotherapy: Use of approved drugs and over‐the‐counter remedies

Journal of inherited metabolic disease, 2000-12, Vol.23 (8), p.767-777

Radin, N. S.

2000

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A role for glycosphingolipid accumulation in the renal hypertrophy of streptozotocin-induced diabetes mellitus

The Journal of clinical investigation, 1993-03, Vol.91 (3), p.797-803

1993

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Infections and glycolipids

Postgraduate medical journal, 2003-03, Vol.79 (929), p.185-185

Radin, N S

2003

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Effects of the glucolipid synthase inhibitor, P4, on functional and phenotypic parameters of murine myeloma cells

British Journal of Cancer, 1999-11, Vol.81 (6), p.952-958

1999

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Abnormalities of glycosphingolipid, sulfatide, and ceramide in the polycystic (cpk/cpk) mouse

Journal of lipid research, 1994-09, Vol.35 (9), p.1611-1618

1994

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Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells. Evidence that ceramide may mediate sphingosine action

The Journal of biological chemistry, 1991-08, Vol.266 (24), p.16092-16097

1991

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Improved Inhibitors of Glucosylceramide Synthase

Journal of biochemistry (Tokyo), 1992-02, Vol.111 (2), p.191-196

1992

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Inhibition of experimental metastasis of murine Lewis lung carcinoma by an inhibitor of glucosylceramide synthase and its possible mechanism of action

Cancer research (Chicago, Ill.), 1990-10, Vol.50 (20), p.6731-6737

1990

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Metabolism of D-[3H]threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, an inhibitor of glucosylceramide synthesis, and the synergistic action of an inhibitor of microsomal monooxygenase

Journal of lipid research, 1991-04, Vol.32 (4), p.713-722

1991

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Modulation of renal epithelial cell growth by glucosylceramide. Association with protein kinase C, sphingosine, and diacylglycerol

The Journal of biological chemistry, 1991-12, Vol.266 (34), p.22968-22974

1991

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The activator protein for glucosylceramide beta-glucosidase from guinea pig liver. Improved isolation method and complete amino acid sequence

The Journal of biological chemistry, 1988-12, Vol.263 (36), p.19597-19601

1988

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Control of kidney size by sex hormones: possible involvement of glucosylceramide

American journal of physiology. Renal physiology, 1992-01, Vol.262 (1), p.24-F29

1992

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Treatment of Gaucher disease with an enzyme inhibitor

Glycoconjugate journal, 1996-04, Vol.13 (2), p.153-157

Radin, N S

1996

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A ceramide analog inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis

Biochemistry (Easton), 1990-07, Vol.29 (26), p.6314-6322

1990

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Metabolic effects of inhibiting glucosylceramide synthesis with PDMP and other substances

Advances in lipid research, 1993, Vol.26, p.183

1993

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Structure and function of renal glycosphingolipids

American journal of physiology. Renal physiology, 1991-03, Vol.260 (3 Pt 2), p.F291-F302

1991

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Glycosphingolipid synthesis and proliferation in a renal cell line grown in high glucose

American journal of physiology. Renal physiology, 1996-03, Vol.270 (3), p.476-F484

1996

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Glycolipid depletion using a ceramide analogue (PDMP) alters growth, adhesion, and membrane lipid organization in human A431 cells

Journal of cellular physiology, 1992-03, Vol.150 (3), p.610-619

1992

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Preparative scale isolation of sphingosine

Journal of lipid research, 1990-12, Vol.31 (12), p.2291-2293

Radin, NS

1990

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Antitumor activity via inhibition of glycosphingolipid biosynthesis

Cancer letters, 1987-12, Vol.38 (1), p.23-30

1987

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Chemotherapy by slowing glucosphingolipid synthesis

Apoptotic death by ceramide: will the real killer please stand up?

Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth

Epithelial glucosphingolipid expression as a determinant of bacterial adherence and cytokine production

Preparation of the active isomer of 1-phenyl-2-decanoylamino-3-morpholino-1-propanol, inhibitor of murine glucocerebroside synthetase

Treating glucosphingolipid disorders by chemotherapy: Use of approved drugs and over‐the‐counter remedies

A role for glycosphingolipid accumulation in the renal hypertrophy of streptozotocin-induced diabetes mellitus

Infections and glycolipids

Effects of the glucolipid synthase inhibitor, P4, on functional and phenotypic parameters of murine myeloma cells

Abnormalities of glycosphingolipid, sulfatide, and ceramide in the polycystic (cpk/cpk) mouse

Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells. Evidence that ceramide may mediate sphingosine action

Improved Inhibitors of Glucosylceramide Synthase

Inhibition of experimental metastasis of murine Lewis lung carcinoma by an inhibitor of glucosylceramide synthase and its possible mechanism of action

Metabolism of D-[3H]threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, an inhibitor of glucosylceramide synthesis, and the synergistic action of an inhibitor of microsomal monooxygenase

Modulation of renal epithelial cell growth by glucosylceramide. Association with protein kinase C, sphingosine, and diacylglycerol

The activator protein for glucosylceramide beta-glucosidase from guinea pig liver. Improved isolation method and complete amino acid sequence

Control of kidney size by sex hormones: possible involvement of glucosylceramide

Treatment of Gaucher disease with an enzyme inhibitor

A ceramide analog inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis

Metabolic effects of inhibiting glucosylceramide synthesis with PDMP and other substances

Structure and function of renal glycosphingolipids

Glycosphingolipid synthesis and proliferation in a renal cell line grown in high glucose

Glycolipid depletion using a ceramide analogue (PDMP) alters growth, adhesion, and membrane lipid organization in human A431 cells

Preparative scale isolation of sphingosine

Antitumor activity via inhibition of glycosphingolipid biosynthesis

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