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Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia

The Journal of clinical investigation, 2001-11, Vol.108 (9), p.1321-1330

2001

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Reverse Transcription Polymerase Chain Reaction for the Rearranged Retinoic Acid Receptor α Clarifies Diagnosis and Detects Minimal Residual Disease in Acute Promyelocytic Leukemia

Proceedings of the National Academy of Sciences - PNAS, 1992-04, Vol.89 (7), p.2694-2698

1992

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Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR-α fusion mRNA

Blood, 1993-09, Vol.82 (6), p.1689-1694

1993

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Initial clinical trial of a selective retinoid X receptor ligand, LGD1069

Journal of clinical oncology, 1997-02, Vol.15 (2), p.790-795

1997

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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

Cell, 1991-08, Vol.66 (4), p.663-674

1991

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Early Mortality and the Retinoic Acid Syndrome in Acute Promyelocytic Leukemia: Impact of Leukocytosis, Low-Dose Chemotherapy, PMN/RAR-α Isoform, and CD13 Expression in Patients Treated With All-Trans Retinoic Acid

Blood, 1994-12, Vol.84 (11), p.3843-3849

1994

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United States Multicenter Study of Arsenic Trioxide in Relapsed Acute Promyelocytic Leukemia

Journal of clinical oncology, 2001-09, Vol.19 (18), p.3852-3860

2001

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Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations : implications for relapse and retinoid resistance in patients with acute promyelocytic leukemia

Blood, 1992-01, Vol.79 (2), p.299-303

1992

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Therapeutic Targeting of Transcription in Acute Promyelocytic Leukemia by Use of an Inhibitor of Histone Deacetylase

JNCI : Journal of the National Cancer Institute, 1998-11, Vol.90 (21), p.1621-1625

1998

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Acute promyelocytic leukemia cell line AP-1060 established as a cytokine-dependent culture from a patient clinically resistant to all-trans retinoic acid and arsenic trioxide

Leukemia, 2004-07, Vol.18 (7), p.1258-1269

2004

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Complete Remission after Treatment of Acute Promyelocytic Leukemia with Arsenic Trioxide

The New England journal of medicine, 1998-11, Vol.339 (19), p.1341-1348

1998

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Clinical study of 9-cis retinoic acid (LGD1057) in acute promyelocytic leukemia

Leukemia, 1998-10, Vol.12 (10), p.1518-1521

1998

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Immunochemical Characterization of Circulating Parathyroid Hormone–Related Protein in Patients with Humoral Hypercalcemia of Cancer

The New England journal of medicine, 1990-04, Vol.322 (16), p.1106-1112

1990

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Arsenic trioxide induces dose- and time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis

Blood, 2000-08, Vol.96 (4), p.1525-1530

2000

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Treatment of acute promyelocytic leukemia with all-trans retinoic acid: an update of the New York experience

Leukemia, 1994-06, Vol.8 (6), p.929-933

1994

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Initial clinical trial of the retinoid receptor pan agonist 9-cis retinoic acid

Clinical cancer research, 1996-03, Vol.2 (3), p.471-475

1996

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Leukocytosis and the Retinoic Acid Syndrome in Patients With Acute Promyelocytic Leukemia Treated With Arsenic Trioxide

Journal of clinical oncology, 2000-07, Vol.18 (13), p.2620-2625

2000

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Acute Promyelocytic Leukemia

The New England journal of medicine, 1993-07, Vol.329 (3), p.177-189

1993

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Constitutive Variability in the Pharmacokinetics of the Natural Retinoid, All-trans-Retinoic Acid, and Its Modulation by Ketoconazole

JNCI : Journal of the National Cancer Institute, 1993-12, Vol.85 (23), p.1921-1926

1993

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Distribution of Trace Levels of Therapeutic Gallium in Bone as Mapped by Synchrotron X-Ray Microscopy

Proceedings of the National Academy of Sciences - PNAS, 1990-06, Vol.87 (11), p.4149-4153

1990

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Rapid Diagnosis of Acute Promyelocytic Leukemia by Immunohistochemical Localization of PML/RAR-α Protein

Blood, 1995-08, Vol.86 (3), p.862-867

1995

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Therapeutic and Neurotoxic Effects of 2-Chlorodeoxyadenosine in Adults With Acute Myeloid Leukemia

Blood, 1994-11, Vol.84 (10), p.3429-3434

1994

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A randomized double-blind study of gallium nitrate compared with etidronate for acute control of cancer-related hypercalcemia

Journal of clinical oncology, 1991-08, Vol.9 (8), p.1467-1475

1991

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Retinoid Resistance in Acute Promyelocytic Leukemia: New Mechanisms, Strategies, and Implications

Blood, 1993-10, Vol.82 (7), p.1949-1953

Raymond, P. Warrell

1993

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Gallium increases bone calcium and crystallite perfection of hydroxyapatite

Calcified tissue international, 1986-12, Vol.39 (6), p.376-381

1986

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Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia

Reverse Transcription Polymerase Chain Reaction for the Rearranged Retinoic Acid Receptor α Clarifies Diagnosis and Detects Minimal Residual Disease in Acute Promyelocytic Leukemia

Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR-α fusion mRNA

Initial clinical trial of a selective retinoid X receptor ligand, LGD1069

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

Early Mortality and the Retinoic Acid Syndrome in Acute Promyelocytic Leukemia: Impact of Leukocytosis, Low-Dose Chemotherapy, PMN/RAR-α Isoform, and CD13 Expression in Patients Treated With All-Trans Retinoic Acid

United States Multicenter Study of Arsenic Trioxide in Relapsed Acute Promyelocytic Leukemia

Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations : implications for relapse and retinoid resistance in patients with acute promyelocytic leukemia

Therapeutic Targeting of Transcription in Acute Promyelocytic Leukemia by Use of an Inhibitor of Histone Deacetylase

Acute promyelocytic leukemia cell line AP-1060 established as a cytokine-dependent culture from a patient clinically resistant to all-trans retinoic acid and arsenic trioxide

Complete Remission after Treatment of Acute Promyelocytic Leukemia with Arsenic Trioxide

Clinical study of 9-cis retinoic acid (LGD1057) in acute promyelocytic leukemia

Immunochemical Characterization of Circulating Parathyroid Hormone–Related Protein in Patients with Humoral Hypercalcemia of Cancer

Arsenic trioxide induces dose- and time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis

Treatment of acute promyelocytic leukemia with all-trans retinoic acid: an update of the New York experience

Initial clinical trial of the retinoid receptor pan agonist 9-cis retinoic acid

Leukocytosis and the Retinoic Acid Syndrome in Patients With Acute Promyelocytic Leukemia Treated With Arsenic Trioxide

Acute Promyelocytic Leukemia

Constitutive Variability in the Pharmacokinetics of the Natural Retinoid, All-trans-Retinoic Acid, and Its Modulation by Ketoconazole

Distribution of Trace Levels of Therapeutic Gallium in Bone as Mapped by Synchrotron X-Ray Microscopy

Rapid Diagnosis of Acute Promyelocytic Leukemia by Immunohistochemical Localization of PML/RAR-α Protein

Therapeutic and Neurotoxic Effects of 2-Chlorodeoxyadenosine in Adults With Acute Myeloid Leukemia

A randomized double-blind study of gallium nitrate compared with etidronate for acute control of cancer-related hypercalcemia

Retinoid Resistance in Acute Promyelocytic Leukemia: New Mechanisms, Strategies, and Implications

Gallium increases bone calcium and crystallite perfection of hydroxyapatite

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