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Purine Nucleoside Phosphorylase. 3. Reversal of Purine Base Specificity by Site-Directed Mutagenesis

Biochemistry (Easton), 1997-09, Vol.36 (39), p.11749-11756

1997

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Three-dimensional structure of human erythrocytic purine nucleoside phosphorylase at 3.2 A resolution

The Journal of biological chemistry, 1990-01, Vol.265 (3), p.1812-1820

1990

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Inhibition of human purine nucleoside phosphorylase by acyclic nucleosides and nucleotides

Biochemical pharmacology, 1987-04, Vol.36 (8), p.1237-1244

1987

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Substrate specificities of 5′-deoxy-5′-methylthioadenosine phosphorylase from Trypanosoma brucei brucei and mammalian cells

Molecular and biochemical parasitology, 1988-01, Vol.27 (2), p.109-118

1988

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5-Iodoribose 1-phosphate, an analog of ribose 1-phosphate. Enzymatic synthesis and kinetic studies with enzymes of purine, pyrimidine, and sugar phosphate metabolism

The Journal of biological chemistry, 1986-01, Vol.261 (2), p.599-607

1986

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Characterization of a defect in the pathway for converting 5‘-deoxy-5‘-methylthioadenosine to methionine in a subline of a cultured heterogeneous human colon carcinoma

The Journal of biological chemistry, 1984-06, Vol.259 (11), p.6715-6719

1984

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Transport of deoxycoformycin in human erythrocytes: Measurement by adenosine deaminase titration and radioisotope assays

Biochemical pharmacology, 1984-12, Vol.33 (24), p.4069-4079

1984

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5′-Deoxy-5′-methylthioadenosine phosphorylase—IV: Biological activity of 2-fluoroadenine-substituted 5′-deoxy-5′ -methylthioadenosine analogs

Biochemical pharmacology, 1987-06, Vol.36 (12), p.1881-1893

1987

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Differential incorporation of 2'-deoxyadenosine into human peripheral lymphocytes

Biochemical pharmacology, 1985-09, Vol.34 (18), p.3353-3360

1985

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Forskolin: A potential antimetastatic agent

International journal of cancer, 1983-12, Vol.32 (6), p.801-804

1983

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Adenosine metabolism in human whole blood: Effects of nucleoside transport inhibitors and phosphate concentration

Biochemical pharmacology, 1988-02, Vol.37 (4), p.621-626

1988

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Role of adenosine uptake and metabolism by blood cells in the antiplatelet actions of dipyridamole, dilazep and nitrobenzylthioinosine

Biochemical pharmacology, 1985-11, Vol.34 (22), p.3965-3972

1985

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Inhibitors of purine nucleoside phosphorylase: effects of 9-deazapurine ribonucleosides and synthesis of 5'-deoxy-5'-iodo-9-deazainosine

Cancer research (Chicago, Ill.), 1986-04, Vol.46 (4 Pt 1), p.1774-1778

1986

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Potentiation of the antiplatelet action of adenosine in whole blood by dipyridamole or dilazep and the cAMP phosphodiesterase inhibitor, RA 233

Thrombosis research, 1986-07, Vol.43 (2), p.161-175

1986

Volltextzugriff (PDF)

Changes in nucleoside transport of HL-60 human promyelocytic cells during N,N-dimethylformamide induced differentiation

Cancer research (Chicago, Ill.), 1986-07, Vol.46 (7), p.3449-3455

1986

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Design of purine nucleoside phosphorylase inhibitors

Federation proceedings, 1986-11, Vol.45 (12), p.2773

1986

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Inhibition of purine nucleoside phosphorylase by 9-(phosphonoalkyl)hypoxanthines

Biochemical pharmacology, 1986-01, Vol.35 (2), p.133-136

1986

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Clinical, pharmacologic, and immunologic effects of 2'-deoxycoformycin

Clinical pharmacology and therapeutics, 1988-11, Vol.44 (5), p.501-509

1988

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The Interaction of the Nucleoside Analogues, Formycins A and B, with Xanthine Oxidase and Hepatic Aldehyde Oxidase

Molecular pharmacology, 1970-05, Vol.6 (3), p.255-265

1970

Volltextzugriff (PDF)

Nonenzymatic glycosylation of erythrocytic proteins in normal and diabetic subjects. Enzymes of nucleoside and nucleotide metabolism

Diabetes (New York, N.Y.), 1985-03, Vol.34 (3), p.251

1985

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Role of plasma adenosine in the antiplatelet action of hl 725, a potent inhibitor of camp phosphodiesterase: Species differences

Thrombosis research, 1987-07, Vol.47 (2), p.191-200

1987

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Inhibition of nucleoside transport by nitrobenzylthioformycin analogs

Biochemical pharmacology, 1990-08, Vol.40 (3), p.615-619

1990

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Conversion of 5'-deoxy-5'-methylthioadenosine and 5'-deoxy-5'-methylthioinosine to methionine in cultured human leukemic cells

Cancer research (Chicago, Ill.), 1983-10, Vol.43 (10), p.4699-4702

1983

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Murine tumor-induced platelet aggregation and coagulation: mechanisms, inhibitors, and species differences

Thrombosis research, 1987-04, Vol.46 (1), p.65-76

1987

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Nucleotidase activities of human peripheral lymphocytes

Biochemical pharmacology, 1985-09, Vol.34 (17), p.3061-3070

1985

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Purine Nucleoside Phosphorylase. 3. Reversal of Purine Base Specificity by Site-Directed Mutagenesis

Three-dimensional structure of human erythrocytic purine nucleoside phosphorylase at 3.2 A resolution

Inhibition of human purine nucleoside phosphorylase by acyclic nucleosides and nucleotides

Substrate specificities of 5′-deoxy-5′-methylthioadenosine phosphorylase from Trypanosoma brucei brucei and mammalian cells

5-Iodoribose 1-phosphate, an analog of ribose 1-phosphate. Enzymatic synthesis and kinetic studies with enzymes of purine, pyrimidine, and sugar phosphate metabolism

Characterization of a defect in the pathway for converting 5‘-deoxy-5‘-methylthioadenosine to methionine in a subline of a cultured heterogeneous human colon carcinoma

Transport of deoxycoformycin in human erythrocytes: Measurement by adenosine deaminase titration and radioisotope assays

5′-Deoxy-5′-methylthioadenosine phosphorylase—IV: Biological activity of 2-fluoroadenine-substituted 5′-deoxy-5′ -methylthioadenosine analogs

Differential incorporation of 2'-deoxyadenosine into human peripheral lymphocytes

Forskolin: A potential antimetastatic agent

Adenosine metabolism in human whole blood: Effects of nucleoside transport inhibitors and phosphate concentration

Role of adenosine uptake and metabolism by blood cells in the antiplatelet actions of dipyridamole, dilazep and nitrobenzylthioinosine

Inhibitors of purine nucleoside phosphorylase: effects of 9-deazapurine ribonucleosides and synthesis of 5'-deoxy-5'-iodo-9-deazainosine

Potentiation of the antiplatelet action of adenosine in whole blood by dipyridamole or dilazep and the cAMP phosphodiesterase inhibitor, RA 233

Changes in nucleoside transport of HL-60 human promyelocytic cells during N,N-dimethylformamide induced differentiation

Design of purine nucleoside phosphorylase inhibitors

Inhibition of purine nucleoside phosphorylase by 9-(phosphonoalkyl)hypoxanthines

Clinical, pharmacologic, and immunologic effects of 2'-deoxycoformycin

The Interaction of the Nucleoside Analogues, Formycins A and B, with Xanthine Oxidase and Hepatic Aldehyde Oxidase

Nonenzymatic glycosylation of erythrocytic proteins in normal and diabetic subjects. Enzymes of nucleoside and nucleotide metabolism

Role of plasma adenosine in the antiplatelet action of hl 725, a potent inhibitor of camp phosphodiesterase: Species differences

Inhibition of nucleoside transport by nitrobenzylthioformycin analogs

Conversion of 5'-deoxy-5'-methylthioadenosine and 5'-deoxy-5'-methylthioinosine to methionine in cultured human leukemic cells

Murine tumor-induced platelet aggregation and coagulation: mechanisms, inhibitors, and species differences

Nucleotidase activities of human peripheral lymphocytes

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