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New Drug Development for Known and Emerging Viruses

1, 2022

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The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease

EMBO molecular medicine, 2009-04, Vol.1 (1), p.37-49

2009

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Potent In Vivo Antiviral Activity of the Herpes Simplex Virus Primase-Helicase Inhibitor BAY 57-1293

Antimicrobial Agents and Chemotherapy, 2002-06, Vol.46 (6), p.1766-1772

2002

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PDZ-Domain-Mediated Interaction of the Eph-Related Receptor Tyrosine Kinase EphB3 and the Ras-Binding Protein AF6 Depends on the Kinase Activity of the Receptor

Proceedings of the National Academy of Sciences - PNAS, 1998-08, Vol.95 (17), p.9779-9784

1998

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Prognostic significance of polo-like kinase (PLK) expression in non-small cell lung cancer

Oncogene, 1997-02, Vol.14 (5), p.543-549

1997

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Structure and Total Synthesis of Lysobactin (Katanosin B)

Angewandte Chemie (International ed.), 2007-01, Vol.46 (12), p.2039-2042

2007

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Biological Characterization of Novel Inhibitors of the Gram-Positive DNA Polymerase IIIC Enzyme

Antimicrobial Agents and Chemotherapy, 2005-03, Vol.49 (3), p.987-995

2005

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Novel Whole-Cell Antibiotic Biosensors for Compound Discovery

Applied and Environmental Microbiology, 2007-10, Vol.73 (20), p.6436-6443

2007

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Inhibition of Hepatitis B Virus Replication by Drug-Induced Depletion of Nucleocapsids

Science (American Association for the Advancement of Science), 2003-02, Vol.299 (5608), p.893-896

2003

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Stimulated trans-acting factor of 50 kDa (Staf50) inhibits HIV-1 replication in human monocyte-derived macrophages

Virology (New York, N.Y.), 2006-12, Vol.356 (1), p.79-94

2006

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Human Immunodeficiency Virus (HIV)-Positive Sera Obtained Shortly after Seroconversion Neutralize Autologous HIV Type 1 Isolates on Primary Macrophages but Not on Lymphocytes

Journal of Virology, 2000-06, Vol.74 (12), p.5403-5411

2000

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Efficacy of a helicase-primase inhibitor in animal models of ocular herpes simplex virus type 1 infection

Journal of ocular pharmacology and therapeutics, 2008-02, Vol.24 (1), p.34-42

2008

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Human serum albumin–polyethylenimine nanoparticles for gene delivery

Journal of controlled release, 2003-09, Vol.92 (1), p.199-208

2003

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Induction and Down-Regulation of PLK, a Human Serine/Threonine Kinase Expressed in Proliferating Cells and Tumors

Proceedings of the National Academy of Sciences - PNAS, 1994-03, Vol.91 (5), p.1736-1740

1994

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Genetic Relationships Determined by a DNA Heteroduplex Mobility Assay: Analysis of HIV-1 env Genes

Science (American Association for the Advancement of Science), 1993-11, Vol.262 (5137), p.1257-1261

1993

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Structure and Total Synthesis of Lysobactin (Katanosin B)

Angewandte Chemie, 2007-03, Vol.119 (12), p.2085-2088

2007

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Pyrido[3,2-e][1,4] diazepine - Synthese und Prüfung auf Anti-HIV-1-Wirkung

Archiv der Pharmazie (Weinheim), 1995, Vol.328 (3), p.247-255

1995

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Synthesis and bioactivity studies of 1-adamantanamine derivatives of peptides

Journal of peptide science, 1995-09, Vol.1 (5), p.303-310

1995

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Polo-like kinase, a novel marker for cellular proliferation

The American journal of pathology, 1997-04, Vol.150 (4), p.1165-1172

1997

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Second-generation non-nucleosidic reverse transcriptase inhibitor HBY097 and HIV-1 viral load

The Lancet (British edition), 1997-05, Vol.349 (9064), p.1517-1517

1997

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Individual Cell Analysis of the Cytokine Repertoire in Human Immunodeficiency Virus-1–Infected Monocytes/Macrophages by a Combination of Immunocytochemistry and In Situ Hybridization

Blood, 1998-06, Vol.91 (12), p.4752-4760

1998

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Frauen in der industriellen Forschung: Ein Alarmsignal für Europas Unternehmen

Europäische Kommission

2003

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A Novel Peptide Aldehyde with Activity against Human Cytomegalovirus in Two Different in Vivo Models

Antiviral chemistry & chemotherapy, 2000-01, Vol.11 (1), p.51-59

2000

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A highly divergent HIV-2-related isolate

Nature (London), 1989-12, Vol.342 (6252), p.948-950

1989

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Antivirals against DNA viruses (hepatitis B and the herpes viruses)

Current opinion in pharmacology, 2004-10, Vol.4 (5), p.453-464

2004

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New Drug Development for Known and Emerging Viruses

The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease

Potent In Vivo Antiviral Activity of the Herpes Simplex Virus Primase-Helicase Inhibitor BAY 57-1293

PDZ-Domain-Mediated Interaction of the Eph-Related Receptor Tyrosine Kinase EphB3 and the Ras-Binding Protein AF6 Depends on the Kinase Activity of the Receptor

Prognostic significance of polo-like kinase (PLK) expression in non-small cell lung cancer

Structure and Total Synthesis of Lysobactin (Katanosin B)

Biological Characterization of Novel Inhibitors of the Gram-Positive DNA Polymerase IIIC Enzyme

Novel Whole-Cell Antibiotic Biosensors for Compound Discovery

Inhibition of Hepatitis B Virus Replication by Drug-Induced Depletion of Nucleocapsids

Stimulated trans-acting factor of 50 kDa (Staf50) inhibits HIV-1 replication in human monocyte-derived macrophages

Human Immunodeficiency Virus (HIV)-Positive Sera Obtained Shortly after Seroconversion Neutralize Autologous HIV Type 1 Isolates on Primary Macrophages but Not on Lymphocytes

Efficacy of a helicase-primase inhibitor in animal models of ocular herpes simplex virus type 1 infection

Human serum albumin–polyethylenimine nanoparticles for gene delivery

Induction and Down-Regulation of PLK, a Human Serine/Threonine Kinase Expressed in Proliferating Cells and Tumors

Genetic Relationships Determined by a DNA Heteroduplex Mobility Assay: Analysis of HIV-1 env Genes

Structure and Total Synthesis of Lysobactin (Katanosin B)

Pyrido[3,2-e][1,4] diazepine - Synthese und Prüfung auf Anti-HIV-1-Wirkung

Synthesis and bioactivity studies of 1-adamantanamine derivatives of peptides

Polo-like kinase, a novel marker for cellular proliferation

Second-generation non-nucleosidic reverse transcriptase inhibitor HBY097 and HIV-1 viral load

Individual Cell Analysis of the Cytokine Repertoire in Human Immunodeficiency Virus-1–Infected Monocytes/Macrophages by a Combination of Immunocytochemistry and In Situ Hybridization

Frauen in der industriellen Forschung: Ein Alarmsignal für Europas Unternehmen

A Novel Peptide Aldehyde with Activity against Human Cytomegalovirus in Two Different in Vivo Models

A highly divergent HIV-2-related isolate

Antivirals against DNA viruses (hepatitis B and the herpes viruses)

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