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Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

Science (American Association for the Advancement of Science), 2011-04, Vol.332 (6029), p.600-603

2011

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Vitamin D Antagonises the Suppressive Effect of Inflammatory Cytokines on CTLA-4 Expression and Regulatory Function

PloS one, 2015-07, Vol.10 (7), p.e0131539-e0131539

2015

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Evidence for Functional P2X4/P2X7 Heteromeric Receptors

Molecular pharmacology, 2007-12, Vol.72 (6), p.1447-1456

2007

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Regulation of P2X₄ receptors by lysosomal targeting, glycan protection and exocytosis

Journal of cell science, 2007-11, Vol.120 (21), p.3838-3849

2007

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Interactions of the anti-FcRn monoclonal antibody, rozanolixizumab, with Fcγ receptors and functional impact on immune cells in vitro

mAbs, 2024, Vol.16 (1), p.2300155-2300155

2024

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Comparison of the intracellular trafficking itinerary of ctla-4 orthologues

PloS one, 2013-04, Vol.8 (4), p.e60903-e60903

2013

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ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages

BMC immunology, 2008-07, Vol.9 (1), p.35-35, Article 35

2008

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An immunofluorescence assay for extracellular matrix components highlights the role of epithelial cells in producing a stable, fibrillar extracellular matrix

Biology open, 2017-10, Vol.6 (10), p.1423-1433

2017

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Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation

Nature immunology, 2022-09, Vol.23 (9), p.1365

2022

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Availability of 25-Hydroxyvitamin D3 to APCs Controls the Balance between Regulatory and Inflammatory T Cell Responses

The Journal of immunology (1950), 2012-12, Vol.189 (11), p.5155-5164

2012

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1,25-Dihydroxyvitamin D3 and IL-2 Combine to Inhibit T Cell Production of Inflammatory Cytokines and Promote Development of Regulatory T Cells Expressing CTLA-4 and FoxP3

The Journal of immunology (1950), 2009-11, Vol.183 (9), p.5458-5467

2009

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Assembly and trafficking of P2X purinergic receptors (Review)

Molecular membrane biology, 2008-01, Vol.25 (4), p.321-331

2008

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Regulation of CTLA‐4 recycling by LRBA and Rab11

Immunology, 2021-09, Vol.164 (1), p.106-119

2021

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Measuring CTLA-4-Dependent Suppressive Function in Regulatory T Cells

Methods in molecular biology (Clifton, N.J.), 2019, Vol.1899, p.87

2019

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A transendocytosis model of CTLA-4 function predicts its suppressive behavior on regulatory T cells

The Journal of immunology (1950), 2015-03, Vol.194 (5), p.2148-2159

2015

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An Uncharged Region within the N Terminus of the P2X6 Receptor Inhibits Its Assembly and Exit from the Endoplasmic Reticulum

Molecular pharmacology, 2006-05, Vol.69 (5), p.1692

2006

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Triazole-derivatized near-infrared cyanine dyes enable local functional fluorescent imaging of ocular inflammation

Biosensors & bioelectronics, 2022-11, Vol.216, p.114623-114623, Article 114623

2022

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Constitutive Clathrin-mediated Endocytosis of CTLA-4 Persists during T Cell Activation

The Journal of biological chemistry, 2012-03, Vol.287 (12), p.9429-9440

2012

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A Transendocytosis Perspective on the CD28/CTLA-4 Pathway

Advances in Immunology, 2014, Vol.124, p.95-136

2014

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Cutting edge: cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells

The Journal of immunology (1950), 2012-08, Vol.189 (3), p.1118-1122

2012

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IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells

The Journal of immunology (1950), 2014-03, Vol.192 (5), p.2195-2201

2014

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CTLA-4 Controls Regulatory T Cell Peripheral Homeostasis and Is Required for Suppression of Pancreatic Islet Autoimmunity

The Journal of immunology (1950), 2009-01, Vol.182 (1), p.274-282

2009

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Abstract 3274: A robust enhancement of cytokine production in a human chronic activation model of T cell exhaustion in vitro through blockade of PD-1/PDL-1 interactions using pembrolizumab or nivolumab; correlation with dissociated tumor immune cell responses

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.3274-3274

2020

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Chapter Four: A Transendocytosis Perspective on the CD28/CTLA-4 Pathway

Advances in immunology, 2014-01, Vol.124, p.95

2014

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Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

Vitamin D Antagonises the Suppressive Effect of Inflammatory Cytokines on CTLA-4 Expression and Regulatory Function

Evidence for Functional P2X4/P2X7 Heteromeric Receptors

Regulation of P2X₄ receptors by lysosomal targeting, glycan protection and exocytosis

Interactions of the anti-FcRn monoclonal antibody, rozanolixizumab, with Fcγ receptors and functional impact on immune cells in vitro

Comparison of the intracellular trafficking itinerary of ctla-4 orthologues

ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages

An immunofluorescence assay for extracellular matrix components highlights the role of epithelial cells in producing a stable, fibrillar extracellular matrix

Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation

Availability of 25-Hydroxyvitamin D3 to APCs Controls the Balance between Regulatory and Inflammatory T Cell Responses

1,25-Dihydroxyvitamin D3 and IL-2 Combine to Inhibit T Cell Production of Inflammatory Cytokines and Promote Development of Regulatory T Cells Expressing CTLA-4 and FoxP3

Assembly and trafficking of P2X purinergic receptors (Review)

Regulation of CTLA‐4 recycling by LRBA and Rab11

Measuring CTLA-4-Dependent Suppressive Function in Regulatory T Cells

A transendocytosis model of CTLA-4 function predicts its suppressive behavior on regulatory T cells

An Uncharged Region within the N Terminus of the P2X6 Receptor Inhibits Its Assembly and Exit from the Endoplasmic Reticulum

Triazole-derivatized near-infrared cyanine dyes enable local functional fluorescent imaging of ocular inflammation

Constitutive Clathrin-mediated Endocytosis of CTLA-4 Persists during T Cell Activation

A Transendocytosis Perspective on the CD28/CTLA-4 Pathway

Cutting edge: cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells

IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells

CTLA-4 Controls Regulatory T Cell Peripheral Homeostasis and Is Required for Suppression of Pancreatic Islet Autoimmunity

A cell-based, SARS-CoV-2 spike protein interaction assay to inform the neutralising capacity of recombinant and patient sera antibodies

Abstract 3274: A robust enhancement of cytokine production in a human chronic activation model of T cell exhaustion in vitro through blockade of PD-1/PDL-1 interactions using pembrolizumab or nivolumab; correlation with dissociated tumor immune cell responses

Chapter Four: A Transendocytosis Perspective on the CD28/CTLA-4 Pathway

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