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Pharmacological Rescue of Conditionally Reprogrammed Cystic Fibrosis Bronchial Epithelial Cells

American journal of respiratory cell and molecular biology, 2017-05, Vol.56 (5), p.568-574

2017

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Enhanced delivery of peptide-morpholino oligonucleotides with a small molecule to correct splicing defects in the lung

Nucleic acids research, 2021-06, Vol.49 (11), p.6100

2021

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Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis

Science translational medicine, 2014-07, Vol.6 (246), p.246ra96

2014

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Treatment of cystic fibrosis airway cells with CFTR modulators reverses aberrant mucus properties via hydration

The European respiratory journal, 2022-02, Vol.59 (2), p.2100185

2022

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DNAJB12 and Hsp70 triage arrested intermediates of N1303K-CFTR for endoplasmic reticulum-associated autophagy

Molecular biology of the cell, 2021-04, Vol.32 (7), p.538-553

2021

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A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases

Science translational medicine, 2022-03, Vol.14 (638), p.eabl6328

2022

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A small-molecule inhibitor and degrader of the RNF5 ubiquitin ligase

Molecular biology of the cell, 2022-11, Vol.33 (13), p.ar120-ar120

2022

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Airway Epithelial Inflammation In Vitro Augments the Rescue of Mutant CFTR by Current CFTR Modulator Therapies

Frontiers in pharmacology, 2021-03, Vol.12, p.628722-628722

2021

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Personalised medicine for non-classic cystic fibrosis resulting from rare CFTR mutations

The European respiratory journal, 2020-07, Vol.56 (1), p.2000062

2020

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The cystic fibrosis airway milieu enhances rescue of F508del in a pre-clinical model

The European respiratory journal, 2018-12, Vol.52 (6), p.1801133

2018

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Accumulation and persistence of ivacaftor in airway epithelia with prolonged treatment

Journal of cystic fibrosis, 2020-09, Vol.19 (5), p.746-751

2020

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Restoration of R117H CFTR folding and function in human airway cells through combination treatment with VX-809 and VX-770

American journal of physiology. Lung cellular and molecular physiology, 2016-09, Vol.311 (3), p.L550-L559

2016

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A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent Pseudomonas aeruginosa Infection

Cells (Basel, Switzerland), 2023-11, Vol.12 (22), p.2618

2023

Volltextzugriff (PDF)

Cystic fibrosis airway inflammation enables elexacaftor/tezacaftor/ivacaftor-mediated rescue of N1303K CFTR mutation

ERJ open research, 2024-01, Vol.10 (1), p.746

2024

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Nasospheroids permit measurements of CFTR-dependent fluid transport

JCI insight, 2017-11, Vol.2 (22)

2017

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Multicenter intestinal current measurements in rectal biopsies from CF and non-CF subjects to monitor CFTR function

PloS one, 2013-09, Vol.8 (9), p.e73905-e73905

2013

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Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia

JCI insight, 2018-02, Vol.3 (3)

2018

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Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia

JCI insight, 2019-04, Vol.4 (7)

2019

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Generation of renewable mouse intestinal epithelial cell monolayers and organoids for functional analyses

BMC cell biology, 2018-08, Vol.19 (1), p.15

2018

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A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent IPseudomonas aeruginosa/I Infection

Cells (Basel, Switzerland), 2023-11, Vol.12 (22)

2023

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Telomere looping in P. sativum (common garden pea)

The Plant journal : for cell and molecular biology, 2003-10, Vol.36 (2), p.271-279

2003

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Bestrophin‐mediated Ca2+ activated Cl‐ conductance of the airway epithelium

The FASEB journal, 2006-03, Vol.20 (4), p.A798-A798

2006

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Reviews

Visual sociology, 1990-12, Vol.5 (2), p.41-47

1990

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Reviews

Visual Sociology, 1990, Vol.5 (2), p.41-47

1990

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Pharmacological Rescue of Conditionally Reprogrammed Cystic Fibrosis Bronchial Epithelial Cells

Enhanced delivery of peptide-morpholino oligonucleotides with a small molecule to correct splicing defects in the lung

Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis

Treatment of cystic fibrosis airway cells with CFTR modulators reverses aberrant mucus properties via hydration

DNAJB12 and Hsp70 triage arrested intermediates of N1303K-CFTR for endoplasmic reticulum-associated autophagy

A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases

A small-molecule inhibitor and degrader of the RNF5 ubiquitin ligase

Airway Epithelial Inflammation In Vitro Augments the Rescue of Mutant CFTR by Current CFTR Modulator Therapies

Personalised medicine for non-classic cystic fibrosis resulting from rare CFTR mutations

The cystic fibrosis airway milieu enhances rescue of F508del in a pre-clinical model

Accumulation and persistence of ivacaftor in airway epithelia with prolonged treatment

Restoration of R117H CFTR folding and function in human airway cells through combination treatment with VX-809 and VX-770

A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent Pseudomonas aeruginosa Infection

Cystic fibrosis airway inflammation enables elexacaftor/tezacaftor/ivacaftor-mediated rescue of N1303K CFTR mutation

Nasospheroids permit measurements of CFTR-dependent fluid transport

Multicenter intestinal current measurements in rectal biopsies from CF and non-CF subjects to monitor CFTR function

Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia

Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia

Generation of renewable mouse intestinal epithelial cell monolayers and organoids for functional analyses

A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent IPseudomonas aeruginosa/I Infection

Telomere looping in P. sativum (common garden pea)

Bestrophin‐mediated Ca2+ activated Cl‐ conductance of the airway epithelium

Reviews

Reviews

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