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Design and Synthesis of N-[(4-Methoxyphenoxy)carbonyl]-N-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a Novel Peroxisome Proliferator-Activated Receptor α/γ Dual Agonist with Efficacious Glucose and Lipid-Lowering Activities

Journal of medicinal chemistry, 2005-03, Vol.48 (6), p.2248-2250

2005

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Muraglitazar, a Novel Dual (α/γ) Peroxisome Proliferator–Activated Receptor Activator, Improves Diabetes and Other Metabolic Abnormalities and Preserves β-Cell Function in db/db Mice

Diabetes (New York, N.Y.), 2006-01, Vol.55 (1), p.240-248

2006

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Tetrazole based amides as growth hormone secretagogues

Bioorganic & medicinal chemistry, 2008-04, Vol.18 (8), p.2536-2539

2008

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Discovery of tertiary aminoacids as dual PPARα/γ agonists-I

Bioorganic & medicinal chemistry letters, 2007-04, Vol.17 (8), p.2312-2316

2007

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Tetrahydroisoquinoline 1-carboxamides as growth hormone secretagogues

Bioorganic & medicinal chemistry letters, 2005-04, Vol.15 (7), p.1799-1802

2005

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Synthesis and biological evaluation of novel pyrrolidine acid analogs as potent dual PPARα/γ agonists

Bioorganic & medicinal chemistry letters, 2015-03, Vol.25 (6), p.1196-1205

2015

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Anti-Epstein-Barr Virus (EBV) Activity of β-l-5-Iododioxolane Uracil Is Dependent on EBV Thymidine Kinase

Antimicrobial Agents and Chemotherapy, 2000-12, Vol.44 (12), p.3278-3284

2000

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Structure−Activity Relationships of l-Dioxolane Uracil Nucleosides as Anti-Epstein Barr Virus Agents

Journal of medicinal chemistry, 1999-06, Vol.42 (12), p.2212-2217

1999

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Discovery of tertiary aminoacids as dual PPARalpha/gamma agonists-I

Bioorganic & medicinal chemistry letters, 2007-04, Vol.17 (8), p.2312-2316

2007

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Asymmetric synthesis of (2′ R,4′ R) and (2′ S,4′ S)-1,3-dioxolanyl triazole C-nucleosides

Tetrahedron, 1999-07, Vol.55 (30), p.9073-9088

1999

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1,3-Dioxolane C-Nucleosides: Asymmetric Synthesis of Four Stereoisomers of 2-[2-(Hydroxymethyl)-1,3-Dioxolan-S-yl)-1,3-Thiazole-4-Carboxamide

Tetrahedron letters, 1995-11, Vol.36 (45), p.8167-8170

1995

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1,3-Dioxolane C-Nucleosides: Asymmetric Synthesis of Four Stereoisomers of 2-[2-(Hydroxymethyl)-1,3-Dioxolan-5-yl)]-1,3-Thiazole-4-Carboxamide

Tetrahedron letters, 1995-11, Vol.36 (45), p.8167-8170

Jinfa, D

1995

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LncRNA MIR31HG functions as a ceRNA to regulate c-Met function by sponging miR-34a in esophageal squamous cell carcinoma

Biomedicine & pharmacotherapy, 2020-08, Vol.128, p.110313-110313, Article 110313

2020

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LncRNA MNX1-AS1 promotes progression of esophageal squamous cell carcinoma by regulating miR-34a/SIRT1 axis

Biomedicine & pharmacotherapy, 2019-08, Vol.116, p.109029-109029, Article 109029

2019

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YAP Inhibits the Apoptosis and Migration of Human Rectal Cancer Cells via Suppression of JNK-Drp1-Mitochondrial Fission-HtrA2/Omi Pathways

Cellular physiology and biochemistry, 2017-01, Vol.44 (5), p.2073-2089

2017

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Stereoselective Synthesis of β, γ‐Fused Bicyclic γ‐Ureasultams via an Intramolecular Mannich and aza‐Michael Addition Cascade

Chemistry : a European journal, 2024-05, Vol.30 (28), p.e202400438-n/a

2024

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In situ synthesis of a gamma-Al2O3 whisker reinforced aluminium matrix composite by cold pressing and sintering

Materials science & engineering. A, Structural materials : properties, microstructure and processing, 2018-01, Vol.709, p.223-231

2018

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The P5-type ATPase Spf1 is required for development and virulence of the rice blast fungus Pyricularia oryzae

Current genetics, 2020-04, Vol.66 (2), p.385-395

2020

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Thallium exposure at low concentration leads to early damage on multiple organs in children: A case study followed-up for four years

Environmental pollution (1987), 2020-03, Vol.258, p.113319, Article 113319

2020

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Long Non-coding RNA ITIH4-AS1 Accelerates the Proliferation and Metastasis of Colorectal Cancer by Activating JAK/STAT3 Signaling

Molecular therapy. Nucleic acids, 2019-12, Vol.18, p.183-193

2019

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Discovery of precision targeting EZH2 degraders for triple-negative breast cancer

European journal of medicinal chemistry, 2022-08, Vol.238, p.114462-114462, Article 114462

2022

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Role refinement of melanin synthesis genes by gene knockout reveals their functional diversity in Pyricularia oryzae strains

Microbiological research, 2021-01, Vol.242, p.126620, Article 126620

2021

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Histone Deacetylase and Enhancer of Zeste Homologue 2 Dual Inhibitors Presenting a Synergistic Effect for the Treatment of Hematological Malignancies

Journal of medicinal chemistry, 2022-10, Vol.65 (19), p.12838-12859

2022

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Synthesis and evaluation of multi-target-directed ligands with BACE-1 inhibitory and Nrf2 agonist activities as potential agents against Alzheimer’s disease

European journal of medicinal chemistry, 2021-07, Vol.219, p.113441-113441, Article 113441

2021

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Design and Synthesis of N-[(4-Methoxyphenoxy)carbonyl]-N-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a Novel Peroxisome Proliferator-Activated Receptor α/γ Dual Agonist with Efficacious Glucose and Lipid-Lowering Activities

Muraglitazar, a Novel Dual (α/γ) Peroxisome Proliferator–Activated Receptor Activator, Improves Diabetes and Other Metabolic Abnormalities and Preserves β-Cell Function in db/db Mice

Tetrazole based amides as growth hormone secretagogues

Discovery of tertiary aminoacids as dual PPARα/γ agonists-I

Tetrahydroisoquinoline 1-carboxamides as growth hormone secretagogues

Discovery of a Tetrazole-Based Growth Hormone Secretagogue: 4-(Hydroxybutyl)carbamic Acid 2-{5-[1-(2-Amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl Ester (BMS-317180)

Synthesis and biological evaluation of novel pyrrolidine acid analogs as potent dual PPARα/γ agonists

Anti-Epstein-Barr Virus (EBV) Activity of β-l-5-Iododioxolane Uracil Is Dependent on EBV Thymidine Kinase

Structure−Activity Relationships of l-Dioxolane Uracil Nucleosides as Anti-Epstein Barr Virus Agents

Discovery of tertiary aminoacids as dual PPARalpha/gamma agonists-I

Asymmetric synthesis of (2′ R,4′ R) and (2′ S,4′ S)-1,3-dioxolanyl triazole C-nucleosides

1,3-Dioxolane C-Nucleosides: Asymmetric Synthesis of Four Stereoisomers of 2-[2-(Hydroxymethyl)-1,3-Dioxolan-S-yl)-1,3-Thiazole-4-Carboxamide

1,3-Dioxolane C-Nucleosides: Asymmetric Synthesis of Four Stereoisomers of 2-[2-(Hydroxymethyl)-1,3-Dioxolan-5-yl)]-1,3-Thiazole-4-Carboxamide

LncRNA MIR31HG functions as a ceRNA to regulate c-Met function by sponging miR-34a in esophageal squamous cell carcinoma

LncRNA MNX1-AS1 promotes progression of esophageal squamous cell carcinoma by regulating miR-34a/SIRT1 axis

YAP Inhibits the Apoptosis and Migration of Human Rectal Cancer Cells via Suppression of JNK-Drp1-Mitochondrial Fission-HtrA2/Omi Pathways

Stereoselective Synthesis of β, γ‐Fused Bicyclic γ‐Ureasultams via an Intramolecular Mannich and aza‐Michael Addition Cascade

In situ synthesis of a gamma-Al2O3 whisker reinforced aluminium matrix composite by cold pressing and sintering

The P5-type ATPase Spf1 is required for development and virulence of the rice blast fungus Pyricularia oryzae

Thallium exposure at low concentration leads to early damage on multiple organs in children: A case study followed-up for four years

Long Non-coding RNA ITIH4-AS1 Accelerates the Proliferation and Metastasis of Colorectal Cancer by Activating JAK/STAT3 Signaling

Discovery of precision targeting EZH2 degraders for triple-negative breast cancer

Role refinement of melanin synthesis genes by gene knockout reveals their functional diversity in Pyricularia oryzae strains

Histone Deacetylase and Enhancer of Zeste Homologue 2 Dual Inhibitors Presenting a Synergistic Effect for the Treatment of Hematological Malignancies

Synthesis and evaluation of multi-target-directed ligands with BACE-1 inhibitory and Nrf2 agonist activities as potential agents against Alzheimer’s disease

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