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Selective Elimination of Human Pluripotent Stem Cells by an Oleate Synthesis Inhibitor Discovered in a High-Throughput Screen

Cell stem cell, 2013-02, Vol.12 (2), p.167-179

2013

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Synthetic thick filaments: A new avenue for better understanding the myosin super-relaxed state in healthy, diseased, and mavacamten-treated cardiac systems

The Journal of biological chemistry, 2021-01, Vol.296, p.100114-100114, Article 100114

2021

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Metal Impurities Cause False Positives in High-Throughput Screening Campaigns

ACS medicinal chemistry letters, 2013-02, Vol.4 (2), p.197-200

2013

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A Small Molecule Ubiquitination Inhibitor Blocks NF-κB-dependent Cytokine Expression in Cells and Rats

The Journal of biological chemistry, 2002-06, Vol.277 (26), p.23573-23581

2002

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Defining the arachidonic acid binding site of human 15-lipoxygenase. Molecular modeling and mutagenesis

The Journal of biological chemistry, 1996-10, Vol.271 (41), p.25412-25418

1996

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Mechanisms of a novel regulatory light chain-dependent cardiac myosin inhibitor

The Journal of general physiology, 2024-10, Vol.156 (10)

2024

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Two Small Molecule Inhibitors of Myosin Decrease Force and Increase Rates of Relaxation in Demembranated Rat Left Ventricular Tissue

Biophysical journal, 2020-02, Vol.118 (3), p.327a-327a

2020

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Synthetic thick filaments: A new avenue for better understanding the myosin super-relaxed state in healthy, disease, and mavacamten-treated cardiac systems

The Journal of biological chemistry, 2020-12, p.100114

2020

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Identification of a Specific Methionine in Mammalian 15-Lipoxygenase Which Is Oxygenated by the Enzyme Product 13-HPODE: Dissociation of Sulfoxide Formation from Self-Inactivation

Biochemistry (Easton), 1995-05, Vol.34 (21), p.7069-7079

1995

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Near-infrared circular dichroism and magnetic circular dichroism and x-ray absorption spectral comparison of the non-heme ferrous active sites of plant and mammalian 15-lipoxygenases

Journal of the American Chemical Society, 1995-04, Vol.117 (15), p.4316-4327

1995

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A trinuclear copper(I) complex: reaction with dioxygen and the formation of a hexanuclear copper(II) cluster

Inorganic chemistry, 1990-07, Vol.29 (14), p.2549-2551

1990

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Defining the Arachidonic Acid Binding Site of Human 15-Lipoxygenase

The Journal of biological chemistry, 1996-10, Vol.271 (41), p.25412-25418

1996

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A model of arachidonic acid binding for 15-lipoxygenase

Advances in experimental medicine and biology, 1997, Vol.433, p.435

1997

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Abstract 15707: MYK-491, a Novel Small-Molecule Cardiac Myosin Activator Increases Cardiac Systolic Function and Preserves Mechanical Efficiency: Pre-Clinical in vivo and in vitro Evidence

Circulation (New York, N.Y.), 2019-11, Vol.140 (Suppl_1 Suppl 1), p.A15707-A15707

2019

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Clinical significance of pain in patients with chronic heart failure

Chinese medical journal, 2012-09, Vol.125 (18), p.3223-3227

2012

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Dioxygen mediated oxo-transfer to an amine and oxidative N-dealkylation chemistry with a dinuclear copper complex

Chemical communications (Cambridge, England), 2001-01 (7), p.631-632

2001

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A Small Molecule Ubiquitination Inhibitor Blocks NF-ÎºB-dependent Cytokine Expression in Cells and Rats

The Journal of biological chemistry, 2002-06, Vol.277 (26), p.23573

2002

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Dioxygen reactivity with new di- and trinuclear copper(I) complexes

Journal of inorganic biochemistry, 1992-07, Vol.47 (3), p.50-50

1992

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Magnetic circular dichroism spectroscopy of non-heme ferrous active sites: methodology and application to soybean and mammalian lipoxygenases

Journal of inorganic biochemistry, 1995-08, Vol.59 (2-3), p.391-391

1995

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EPR Definition of the Non-Heme Ferric Active Sites of Mammalian 15-Lipoxygenases: Major Spectral Differences Relative to Human 5-Lipoxygenases and Plant Lipoxygenases and Their Ligand Field Origin

Journal of the American Chemical Society, 1995-07, Vol.117 (28), p.7422-7427

1995

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Synthesis, characterization and dioxygen-reactivity of trinuclear and dinuclear copper(I) complexes

Gan, Qing-Fen

1993

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Impact of potentially lethal ventricular arrhythmias on long-term outcome in patients with chronic heart failure

Chinese medical journal, 2012-02, Vol.125 (4), p.563-568

2012

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Plasma exchange-centered artificial liver support system in hepatitis B virus-related acute-on- chronic liver failure： a nationwide prospective multicenter study in China

Hepatobiliary & pancreatic diseases international, 2016-06, Vol.15 (3), p.275-281

2016

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Selective Elimination of Human Pluripotent Stem Cells by an Oleate Synthesis Inhibitor Discovered in a High-Throughput Screen

Synthetic thick filaments: A new avenue for better understanding the myosin super-relaxed state in healthy, diseased, and mavacamten-treated cardiac systems

Metal Impurities Cause False Positives in High-Throughput Screening Campaigns

A Small Molecule Ubiquitination Inhibitor Blocks NF-κB-dependent Cytokine Expression in Cells and Rats

Defining the arachidonic acid binding site of human 15-lipoxygenase. Molecular modeling and mutagenesis

Mechanisms of a novel regulatory light chain-dependent cardiac myosin inhibitor

Two Small Molecule Inhibitors of Myosin Decrease Force and Increase Rates of Relaxation in Demembranated Rat Left Ventricular Tissue

Synthetic thick filaments: A new avenue for better understanding the myosin super-relaxed state in healthy, disease, and mavacamten-treated cardiac systems

Identification of a Specific Methionine in Mammalian 15-Lipoxygenase Which Is Oxygenated by the Enzyme Product 13-HPODE: Dissociation of Sulfoxide Formation from Self-Inactivation

Near-infrared circular dichroism and magnetic circular dichroism and x-ray absorption spectral comparison of the non-heme ferrous active sites of plant and mammalian 15-lipoxygenases

A trinuclear copper(I) complex: reaction with dioxygen and the formation of a hexanuclear copper(II) cluster

Defining the Arachidonic Acid Binding Site of Human 15-Lipoxygenase

A model of arachidonic acid binding for 15-lipoxygenase

Abstract 15707: MYK-491, a Novel Small-Molecule Cardiac Myosin Activator Increases Cardiac Systolic Function and Preserves Mechanical Efficiency: Pre-Clinical in vivo and in vitro Evidence

Clinical significance of pain in patients with chronic heart failure

Dioxygen mediated oxo-transfer to an amine and oxidative N-dealkylation chemistry with a dinuclear copper complex

A Small Molecule Ubiquitination Inhibitor Blocks NF-ÎºB-dependent Cytokine Expression in Cells and Rats

Dioxygen reactivity with new di- and trinuclear copper(I) complexes

Magnetic circular dichroism spectroscopy of non-heme ferrous active sites: methodology and application to soybean and mammalian lipoxygenases

EPR Definition of the Non-Heme Ferric Active Sites of Mammalian 15-Lipoxygenases: Major Spectral Differences Relative to Human 5-Lipoxygenases and Plant Lipoxygenases and Their Ligand Field Origin

Synthesis, characterization and dioxygen-reactivity of trinuclear and dinuclear copper(I) complexes

Impact of potentially lethal ventricular arrhythmias on long-term outcome in patients with chronic heart failure

Plasma exchange-centered artificial liver support system in hepatitis B virus-related acute-on- chronic liver failure： a nationwide prospective multicenter study in China

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