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Combined intermittent fasting and ERK inhibition enhance the anti-tumor effects of chemotherapy via the GSK3β-SIRT7 axis

Nature communications, 2021-08, Vol.12 (1), p.5058-5058, Article 5058

2021

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SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis

Nature communications, 2017-08, Vol.8 (1), p.318-14, Article 318

2017

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Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice

eLife, 2020-06, Vol.9

2020

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CRISPR screening identifies PRMT1 as a key pro-ferroptotic gene via a two-layer regulatory mechanism

Cell reports (Cambridge), 2024-09, Vol.43 (9), p.114662, Article 114662

2024

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Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria

eLife, 2018-05, Vol.7

2018

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Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity

Cell reports (Cambridge), 2024-04, Vol.43 (4), p.114003-114003, Article 114003

2024

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PML2‐mediated thread‐like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome

Aging cell, 2020-06, Vol.19 (6), p.e13147-n/a

2020

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Advances in pharmacological interventions of aging in mice

Translational medicine of aging, 2019, Vol.3, p.116-120

2019

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A small-molecule compound D6 overcomes EGFR-T790M-mediated resistance in non-small cell lung cancer

Communications biology, 2021-12, Vol.4 (1), p.1391-13, Article 1391

2021

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Lamin A buffers CK2 kinase activity to modulate aging in a progeria mouse model

Science advances, 2019-03, Vol.5 (3), p.eaav5078-eaav5078

2019

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Pharmaceutical Intervention of Aging

Aging and Aging-Related Diseases, 2018, Vol.1086, p.235-254

2018

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Deacetylase-independent function of SIRT6 couples GATA4 transcription factor and epigenetic activation against cardiomyocyte apoptosis

Nucleic acids research, 2020-05, Vol.48 (9), p.4992-5005

2020

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SIRT7 activates quiescent hair follicle stem cells to ensure hair growth in mice

The EMBO journal, 2020-09, Vol.39 (18), p.e104365-n/a

2020

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HDAC8 cooperates with SMAD3/4 complex to suppress SIRT7 and promote cell survival and migration

Nucleic acids research, 2020-04, Vol.48 (6), p.2912-2923

2020

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A SIRT1-centered circuitry regulates breast cancer stemness and metastasis

Oncogene, 2018-12, Vol.37 (49), p.6299-6315

2018

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Sirt1 Protects Subventricular Zone-Derived Neural Stem Cells from DNA Double-Strand Breaks and Contributes to Olfactory Function Maintenance in Aging Mice

Stem cells (Dayton, Ohio), 2022-05, Vol.40 (5), p.493-507

2022

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SIRT 7 activates quiescent hair follicle stem cells to ensure hair growth in mice

The EMBO journal, 2020-09, Vol.39 (18)

2020

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Vascular endothelium-targeted Sirt7 gene therapy rejuvenates blood vessels and extends life span in a Hutchinson-Gilford progeria model

Science advances, 2020-02, Vol.6 (8), p.eaay5556-eaay5556

2020

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Reactivation of MAPK-SOX2 pathway confers ferroptosis sensitivity in KRASG12C inhibitor resistant tumors

Redox biology, 2024-11, p.103419, Article 103419

2024

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mTORC1‐PGC1 axis regulates mitochondrial remodeling during reprogramming

The FEBS journal, 2020-01, Vol.287 (1), p.108-121

2020

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mTORC 1‐ PGC 1 axis regulates mitochondrial remodeling during reprogramming

The FEBS journal, 2020-01, Vol.287 (1), p.108-121

2020

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SIRT7 couples light-driven body temperature cues to hepatic circadian phase coherence and gluconeogenesis

Nature metabolism, 2019-11, Vol.1 (11), p.1141-1156

2019

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An exploratory study on the aqueous Cr(VI) removal by the sulfate reducing sludge-based biochar

Separation and purification technology, 2021-12, Vol.276, p.119314, Article 119314

2021

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Nitrogen-doped carbonized polyaniline (N-CPANI) for peroxydisulfate (PDS) activation towards efficient degradation of doxycycline (DOX) via the non-radical pathway dominated by electron transfer

Chemical engineering journal (Lausanne, Switzerland : 1996), 2023-02, Vol.453, p.139810, Article 139810

2023

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Nitrogen and phosphorus co-doped porous carbons (NPCs) for peroxydisulfate (PDS) activation towards tetracycline degradation: Defects enhanced adsorption and non-radical mechanism dominated by electron transfer

Chemical engineering journal (Lausanne, Switzerland : 1996), 2023-01, Vol.455, p.140615, Article 140615

2023

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Combined intermittent fasting and ERK inhibition enhance the anti-tumor effects of chemotherapy via the GSK3β-SIRT7 axis

SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis

Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice

CRISPR screening identifies PRMT1 as a key pro-ferroptotic gene via a two-layer regulatory mechanism

Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria

Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity

PML2‐mediated thread‐like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome

Advances in pharmacological interventions of aging in mice

A small-molecule compound D6 overcomes EGFR-T790M-mediated resistance in non-small cell lung cancer

Lamin A buffers CK2 kinase activity to modulate aging in a progeria mouse model

Pharmaceutical Intervention of Aging

Deacetylase-independent function of SIRT6 couples GATA4 transcription factor and epigenetic activation against cardiomyocyte apoptosis

SIRT7 activates quiescent hair follicle stem cells to ensure hair growth in mice

HDAC8 cooperates with SMAD3/4 complex to suppress SIRT7 and promote cell survival and migration

A SIRT1-centered circuitry regulates breast cancer stemness and metastasis

Sirt1 Protects Subventricular Zone-Derived Neural Stem Cells from DNA Double-Strand Breaks and Contributes to Olfactory Function Maintenance in Aging Mice

SIRT 7 activates quiescent hair follicle stem cells to ensure hair growth in mice

Vascular endothelium-targeted Sirt7 gene therapy rejuvenates blood vessels and extends life span in a Hutchinson-Gilford progeria model

Reactivation of MAPK-SOX2 pathway confers ferroptosis sensitivity in KRASG12C inhibitor resistant tumors

mTORC1‐PGC1 axis regulates mitochondrial remodeling during reprogramming

mTORC 1‐ PGC 1 axis regulates mitochondrial remodeling during reprogramming

SIRT7 couples light-driven body temperature cues to hepatic circadian phase coherence and gluconeogenesis

An exploratory study on the aqueous Cr(VI) removal by the sulfate reducing sludge-based biochar

Nitrogen-doped carbonized polyaniline (N-CPANI) for peroxydisulfate (PDS) activation towards efficient degradation of doxycycline (DOX) via the non-radical pathway dominated by electron transfer

Nitrogen and phosphorus co-doped porous carbons (NPCs) for peroxydisulfate (PDS) activation towards tetracycline degradation: Defects enhanced adsorption and non-radical mechanism dominated by electron transfer

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