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Abstract 1808: Discovery of highly selective novel MTA-cooperative PRMT5 inhibitors for the treatment of cancers

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.1808-1808

2024

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Abstract 3943: Discovery of a novel menin-MLL inhibitor for potential treatment of MLLr leukemias and NPM1c AML

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.3943-3943

2022

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Synthesis and evaluation of aminomethyl dihydrocinnamates as a new class of PPAR ligands

Bioorganic & medicinal chemistry letters, 2006-12, Vol.16 (24), p.6328-6333

2006

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Abstract B129: Preclinical studies with DCC-3116, an ULK kinase inhibitor designed to inhibit autophagy as a potential strategy to address mutant RAS cancers

Molecular cancer therapeutics, 2019-12, Vol.18 (12_Supplement), p.B129-B129

2019

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Synthesis of (.alpha.,.alpha.-difluoroalkyl)phosphonates by displacement of primary triflates

Journal of organic chemistry, 1993-11, Vol.58 (23), p.6174-6176

1993

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Synthesis of the (α,α-difluoroalkyl)phosphonate analogue of phosphoserine

Tetrahedron letters, 1994-08, Vol.35 (35), p.6445-6448

1994

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GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2

Nature (London), 1998-12, Vol.396 (6712), p.674-679

1998

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Research and application of big data technology in China southern grid

2016 IEEE International Conference on Power System Technology (POWERCON), 2016, p.1-6

2016

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Research on new principle of pole discrepancy protection based on voltage phasor difference

2016 IEEE International Conference on Power System Technology (POWERCON), 2016, p.1-6

2016

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In vitro studies on L-771,688 (SNAP 6383), a new potent and selective α1A-adrenoceptor antagonist

European journal of pharmacology, 2000-12, Vol.409 (3), p.301-312

2000

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GABAB receptors function as a heteromeric assembly of the subunits GABABR1 and GABABR2

Nature (London), 1998-12, Vol.396 (6712), p.674-679

1998

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Ready Access to Fluorinated Phosphonate Mimics of Secondary Phosphates. Synthesis of the (α,α-Difluoroalkyl)phosphonate Analogues of l-Phosphoserine, l-Phosphoallothreonine, and l-Phosphothreonine

Journal of organic chemistry, 1996-07, Vol.61 (14), p.4666-4675

1996

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Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 2. Approaches to eliminate opioid agonist metabolites via modification of linker and 4-methoxycarbonyl-4-phenylpiperidine moiety

Journal of medicinal chemistry, 1999-11, Vol.42 (23), p.4778-4793

1999

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Enantiomerically enriched α-vinyl amino acids via lipase-mediated “reverse transesterification”

Tetrahedron letters, 1994-11, Vol.35 (47), p.8743-8746

1994

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The α,α-Difluorinated Phosphonate L-pSer-Analogue: An Accessible Chemical Tool for Studying Kinase- Dependent Signal Transduction

Chemistry & biology, 2009-09, Vol.16 (9), p.928-936

2009

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Synthesis and evaluation of furo[3,4- d ]pyrimidinones as selective α 1a -adrenergic receptor antagonists

Bioorganic & medicinal chemistry letters, 2000-01, Vol.10 (2), p.175-178

2000

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Synthesis and evaluation of furo[3,4-d]pyrimidinones as selective α1a-Adrenergic receptor antagonists

Bioorganic & medicinal chemistry letters, 2000, Vol.10 (2), p.175-178

2000

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Displacement of Sugar Triflates with C-Nucleophiles: D-Glucopyranose and D-Ribofuranose Chain Extension and Functionalization

Synthetic communications, 1994-06, Vol.24 (11), p.1519-1530

1994

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De Novo Design of a Novel Oxazolidinone Analogue as a Potent and Selective α 1A Adrenergic Receptor Antagonist with High Oral Bioavailability

Journal of medicinal chemistry, 2000-07, Vol.43 (15), p.2775-2778

2000

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In vitro studies on L-771,688 (SNAP 6383), a new potent and selective α 1A-adrenoceptor antagonist

European journal of pharmacology, 2000, Vol.409 (3), p.301-312

2000

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De Novo Design of a Novel Oxazolidinone Analogue as a Potent and Selective α1A Adrenergic Receptor Antagonist with High Oral Bioavailability

Journal of medicinal chemistry, 2000-07, Vol.43 (15), p.2775-2778

2000

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GABA B receptors function as a heteromeric assembly of the subunits GABA B R1 and GABA B R2

Nature (London), 1998-12, Vol.396 (6712), p.674-679

1998

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GABA sub(B) receptors function as a heteromeric assembly of the subunits GABA sub(B)R1 and GABA sub(B)R2

Nature (London), 1998-12, Vol.396 (6712), p.674-679

1998

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Abstract 1808: Discovery of highly selective novel MTA-cooperative PRMT5 inhibitors for the treatment of cancers

Abstract 3943: Discovery of a novel menin-MLL inhibitor for potential treatment of MLLr leukemias and NPM1c AML

Synthesis and evaluation of aminomethyl dihydrocinnamates as a new class of PPAR ligands

Abstract B129: Preclinical studies with DCC-3116, an ULK kinase inhibitor designed to inhibit autophagy as a potential strategy to address mutant RAS cancers

Synthesis of (.alpha.,.alpha.-difluoroalkyl)phosphonates by displacement of primary triflates

Synthesis of the (α,α-difluoroalkyl)phosphonate analogue of phosphoserine

GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2

Research and application of big data technology in China southern grid

Research on new principle of pole discrepancy protection based on voltage phasor difference

In vitro studies on L-771,688 (SNAP 6383), a new potent and selective α1A-adrenoceptor antagonist

Design and Synthesis of Novel α1 a Adrenoceptor-Selective Antagonists. 2. Approaches To Eliminate Opioid Agonist Metabolites via Modification of Linker and 4-Methoxycarbonyl-4-phenylpiperidine Moiety

GABAB receptors function as a heteromeric assembly of the subunits GABABR1 and GABABR2

Ready Access to Fluorinated Phosphonate Mimics of Secondary Phosphates. Synthesis of the (α,α-Difluoroalkyl)phosphonate Analogues of l-Phosphoserine, l-Phosphoallothreonine, and l-Phosphothreonine

Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 2. Approaches to eliminate opioid agonist metabolites via modification of linker and 4-methoxycarbonyl-4-phenylpiperidine moiety

Enantiomerically enriched α-vinyl amino acids via lipase-mediated “reverse transesterification”

The α,α-Difluorinated Phosphonate L-pSer-Analogue: An Accessible Chemical Tool for Studying Kinase- Dependent Signal Transduction

Synthesis and evaluation of furo[3,4- d ]pyrimidinones as selective α 1a -adrenergic receptor antagonists

Synthesis and evaluation of furo[3,4-d]pyrimidinones as selective α1a-Adrenergic receptor antagonists

Displacement of Sugar Triflates with C-Nucleophiles: D-Glucopyranose and D-Ribofuranose Chain Extension and Functionalization

De Novo Design of a Novel Oxazolidinone Analogue as a Potent and Selective α 1A Adrenergic Receptor Antagonist with High Oral Bioavailability

In vitro studies on L-771,688 (SNAP 6383), a new potent and selective α 1A-adrenoceptor antagonist

De Novo Design of a Novel Oxazolidinone Analogue as a Potent and Selective α1A Adrenergic Receptor Antagonist with High Oral Bioavailability

Design and Synthesis of Novel α 1 a Adrenoceptor-Selective Antagonists. 2. Approaches To Eliminate Opioid Agonist Metabolites via Modification of Linker and 4-Methoxycarbonyl-4-phenylpiperidine Moiety

GABA B receptors function as a heteromeric assembly of the subunits GABA B R1 and GABA B R2

GABA sub(B) receptors function as a heteromeric assembly of the subunits GABA sub(B)R1 and GABA sub(B)R2

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