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Connecting copper and cancer: from transition metal signalling to metalloplasia

Nature reviews. Cancer, 2022-02, Vol.22 (2), p.102-113

2022

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Novel metals and metal complexes as platforms for cancer therapy

Current pharmaceutical design, 2010-06, Vol.16 (16), p.1813-1825

2010

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Tea in Health and Disease

Nutrients, 2019-04, Vol.11 (4), p.929

Dou, Q Ping

2019

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Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity

Cancer research (Chicago, Ill.), 2006-11, Vol.66 (21), p.10425-10433

2006

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Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4

Nature (London), 2017-12, Vol.552 (7684), p.194-199

2017

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Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system

Current cancer drug targets, 2014-01, Vol.14 (6), p.517-536

2014

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Targeting the ubiquitin-proteasome system for cancer treatment: discovering novel inhibitors from nature and drug repurposing

Cancer and metastasis reviews, 2017-12, Vol.36 (4), p.717-736

2017

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Celastrol, a triterpene extracted from the Chinese thunder of god vine, is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice

Cancer research (Chicago, Ill.), 2006-05, Vol.66 (9), p.4758-4765

2006

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Targeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer

Current drug targets, 2010-06, Vol.11 (6), p.733-744

2010

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Nanoparticle-mediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance

Journal of controlled release, 2010-01, Vol.141 (2), p.137-144

2010

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Recent Advances in Antabuse (Disulfiram): The Importance of its Metal-binding Ability to its Anticancer Activity

Current medicinal chemistry, 2018-02, Vol.25 (4), p.506-524

2018

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Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination

Oncogene, 2018-04, Vol.37 (14), p.1896-1910

2018

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Targeting the ubiquitin-proteasome system for cancer therapy

Expert opinion on therapeutic targets, 2013-09, Vol.17 (9), p.1091-1108

2013

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The ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention

Current protein & peptide science, 2010-09, Vol.11 (6), p.459-470

2010

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Novel Schiff Base Copper Complexes of Quinoline-2 Carboxaldehyde as Proteasome Inhibitors in Human Prostate Cancer Cells

Journal of medicinal chemistry, 2006-11, Vol.49 (24), p.7242-7246

2006

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Everolimus Inhibits Growth of Gemcitabine‐Resistant Pancreatic Cancer Cells via Induction of Caspase‐Dependent Apoptosis and G2/M Arrest

Journal of cellular biochemistry, 2017-09, Vol.118 (9), p.2722-2730

2017

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A novel anticancer gold(III) dithiocarbamate compound inhibits the activity of a purified 20S proteasome and 26S proteasome in human breast cancer cell cultures and xenografts

Cancer research (Chicago, Ill.), 2006-11, Vol.66 (21), p.10478-10486

2006

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Shikonin extracted from medicinal Chinese herbs exerts anti-inflammatory effect via proteasome inhibition

European journal of pharmacology, 2011-05, Vol.658 (2), p.242-247

2011

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Targeting the ubiquitin-proteasome pathway: an emerging concept in cancer therapy

Current topics in medicinal chemistry, 2011-12, Vol.11 (23), p.2888-2905

2011

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Gold(III)-dithiocarbamato peptidomimetics in the forefront of the targeted anticancer therapy: preclinical studies against human breast neoplasia

PloS one, 2014-01, Vol.9 (1), p.e84248

2014

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Recent Advances in Repurposing Disulfiram and Disulfiram Derivatives as Copper-Dependent Anticancer Agents

Frontiers in molecular biosciences, 2021-09, Vol.8, p.741316-741316

2021

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The tumor proteasome is a primary target for the natural anticancer compound Withaferin A isolated from "Indian winter cherry"

Molecular pharmacology, 2007-02, Vol.71 (2), p.426-437

2007

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Dithiocarbamate-based coordination compounds as potent proteasome inhibitors in human cancer cells

Mini reviews in medicinal chemistry, 2012-10, Vol.12 (12), p.1193-1201

2012

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The role of ferroptosis in lung cancer

Biomarker research, 2021-11, Vol.9 (1), p.82-82, Article 82

2021

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Ni(II), Cu(II), and Zn(II) Diethyldithiocarbamate Complexes Show Various Activities Against the Proteasome in Breast Cancer Cells

Journal of medicinal chemistry, 2008-10, Vol.51 (20), p.6256-6258

2008

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Connecting copper and cancer: from transition metal signalling to metalloplasia

Novel metals and metal complexes as platforms for cancer therapy

Tea in Health and Disease

Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4

Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system

Targeting the ubiquitin-proteasome system for cancer treatment: discovering novel inhibitors from nature and drug repurposing

Celastrol, a triterpene extracted from the Chinese thunder of god vine, is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice

Targeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer

Nanoparticle-mediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance

Recent Advances in Antabuse (Disulfiram): The Importance of its Metal-binding Ability to its Anticancer Activity

Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination

Targeting the ubiquitin-proteasome system for cancer therapy

The ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention

Novel Schiff Base Copper Complexes of Quinoline-2 Carboxaldehyde as Proteasome Inhibitors in Human Prostate Cancer Cells

Everolimus Inhibits Growth of Gemcitabine‐Resistant Pancreatic Cancer Cells via Induction of Caspase‐Dependent Apoptosis and G2/M Arrest

A novel anticancer gold(III) dithiocarbamate compound inhibits the activity of a purified 20S proteasome and 26S proteasome in human breast cancer cell cultures and xenografts

Shikonin extracted from medicinal Chinese herbs exerts anti-inflammatory effect via proteasome inhibition

Targeting the ubiquitin-proteasome pathway: an emerging concept in cancer therapy

Gold(III)-dithiocarbamato peptidomimetics in the forefront of the targeted anticancer therapy: preclinical studies against human breast neoplasia

Recent Advances in Repurposing Disulfiram and Disulfiram Derivatives as Copper-Dependent Anticancer Agents

The tumor proteasome is a primary target for the natural anticancer compound Withaferin A isolated from "Indian winter cherry"

Dithiocarbamate-based coordination compounds as potent proteasome inhibitors in human cancer cells

The role of ferroptosis in lung cancer

Ni(II), Cu(II), and Zn(II) Diethyldithiocarbamate Complexes Show Various Activities Against the Proteasome in Breast Cancer Cells

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