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Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

Angiogenesis (London), 2012-06, Vol.15 (2), p.171-185

2012

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Human Serum Albumin Mitigates Formation of Fatty Acid Particles in Polysorbate-Containing Solutions

Journal of pharmaceutical sciences, 2022-11, Vol.111 (11), p.3185-3188

2022

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Comprehensive chromatographic assessment of forced degraded in vitro transcribed mRNA

Journal of Chromatography A, 2024-05, Vol.1722, p.464885, Article 464885

2024

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Comparison of capillary electrophoresis-based methods for the analytical characterization of purity and stability of in vitro transcribed mRNA

Journal of pharmaceutical and biomedical analysis, 2024-10, Vol.249, p.116352, Article 116352

2024

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Development of a platform method for rapid detection and characterization of domain-specific post-translational modifications in bispecific antibodies

Journal of pharmaceutical and biomedical analysis, 2024-07, Vol.244, p.116120-116120, Article 116120

2024

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High-sensitivity and high-resolution therapeutic antibody charge variant and impurity characterization by microfluidic native capillary electrophoresis-mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2023-01, Vol.223, p.115147-115147, Article 115147

2023

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A single-nucleotide resolution capillary gel electrophoresis workflow for poly(A) tail characterization in the development of mRNA therapeutics and vaccines

Journal of pharmaceutical and biomedical analysis, 2023-11, Vol.236, p.115692-115692, Article 115692

2023

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VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade

Proceedings of the National Academy of Sciences - PNAS, 2007-11, Vol.104 (47), p.18363-18370

2007

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Deciphering the High Viscosity of a Therapeutic Monoclonal Antibody in High Concentration Formulations by Microdialysis-Hydrogen/Deuterium Exchange Mass Spectrometry

Journal of pharmaceutical sciences, 2022-05, Vol.111 (5), p.1335-1345

2022

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Enrichment strategy and initial characterization of heterodimers enriched from a co-formulated cocktail of therapeutic antibodies against SARS-COV-2

mAbs, 2024, Vol.16 (1), p.2338301-2338301

2024

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Cytokine traps: multi-component, high-affinity blockers of cytokine action

Nature medicine, 2003-01, Vol.9 (1), p.47-52

2003

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Comprehensive biophysical characterization of AAV-AAVR interaction uncovers serotype- and pH-dependent interaction

Journal of pharmaceutical and biomedical analysis, 2023-09, Vol.234, p.115562-115562, Article 115562

2023

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A Biparatopic Antibody That Modulates MET Trafficking Exhibits Enhanced Efficacy Compared with Parental Antibodies in MET-Driven Tumor Models

Clinical cancer research, 2020-03, Vol.26 (6), p.1408-1419

2020

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Mitigating target interference in bridging immunogenicity assay with target-blocking reagents and mild basic pH

Bioanalysis, 2019-09, Vol.11 (17), p.1569-1580

2019

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Mode of Selectivity in Cyclic AMP Receptor Protein-Dependent Promoters in Escherichia coli

Biochemistry (Easton), 1996-01, Vol.35 (4), p.1162-1172

1996

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Aflibercept exhibits VEGF binding stoichiometry distinct from bevacizumab and does not support formation of immune-like complexes

Angiogenesis (London), 2016-07, Vol.19 (3), p.389-406

2016

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Escherichia coli cAMP Receptor Protein−DNA Complexes. 2. Structural Asymmetry of DNA Bending

Biochemistry (Easton), 1998-04, Vol.37 (15), p.5201-5210

1998

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Escherichia coli cAMP Receptor Protein−DNA Complexes. 1. Energetic Contributions of Half-Sites and Flanking Sequences in DNA Recognition

Biochemistry (Easton), 1998-04, Vol.37 (15), p.5194-5200

1998

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Effect of the B ring and the C-7 substituent on the kinetics of colchicinoid-tubulin associations

Biochemistry (Easton), 1993-03, Vol.32 (9), p.2329-2336

1993

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Matrix interference from Fc-Fc interactions in immunoassays for detecting human IgG4 therapeutics

Bioanalysis, 2015-01, Vol.7 (20), p.2701-2712

2015

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Conformational analysis of colchicinoids containing an electron-deficient aromatic ring on the B ring

Journal of organic chemistry, 1993-05, Vol.58 (10), p.2751-2759

1993

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Effect of B-ring substituents on absorption and circular dichroic spectra of colchicine analogs

Biochemistry (Easton), 1992-02, Vol.31 (7), p.2034-2039

1992

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Role of the B-ring substituent in the fluorescence of colchicinoid-tubulin and allocolchicinoid-tubulin complexes

Biochemistry (Easton), 1992-08, Vol.31 (31), p.7086-7093

1992

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Kinetic and spectral properties of colchicine B-ring analogs binding to tubulin

Pyles, Erica Anne

1992

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The interaction of land-use history and tree species diversity in driving variation in the aboveground biomass of urban versus non-urban tropical forests

Ecological indicators, 2021-10, Vol.129, p.107915, Article 107915

2021

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Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

Human Serum Albumin Mitigates Formation of Fatty Acid Particles in Polysorbate-Containing Solutions

Comprehensive chromatographic assessment of forced degraded in vitro transcribed mRNA

Comparison of capillary electrophoresis-based methods for the analytical characterization of purity and stability of in vitro transcribed mRNA

Development of a platform method for rapid detection and characterization of domain-specific post-translational modifications in bispecific antibodies

High-sensitivity and high-resolution therapeutic antibody charge variant and impurity characterization by microfluidic native capillary electrophoresis-mass spectrometry

A single-nucleotide resolution capillary gel electrophoresis workflow for poly(A) tail characterization in the development of mRNA therapeutics and vaccines

VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade

Deciphering the High Viscosity of a Therapeutic Monoclonal Antibody in High Concentration Formulations by Microdialysis-Hydrogen/Deuterium Exchange Mass Spectrometry

Enrichment strategy and initial characterization of heterodimers enriched from a co-formulated cocktail of therapeutic antibodies against SARS-COV-2

Cytokine traps: multi-component, high-affinity blockers of cytokine action

Comprehensive biophysical characterization of AAV-AAVR interaction uncovers serotype- and pH-dependent interaction

A Biparatopic Antibody That Modulates MET Trafficking Exhibits Enhanced Efficacy Compared with Parental Antibodies in MET-Driven Tumor Models

Mitigating target interference in bridging immunogenicity assay with target-blocking reagents and mild basic pH

Mode of Selectivity in Cyclic AMP Receptor Protein-Dependent Promoters in Escherichia coli

Aflibercept exhibits VEGF binding stoichiometry distinct from bevacizumab and does not support formation of immune-like complexes

Escherichia coli cAMP Receptor Protein−DNA Complexes. 2. Structural Asymmetry of DNA Bending

Escherichia coli cAMP Receptor Protein−DNA Complexes. 1. Energetic Contributions of Half-Sites and Flanking Sequences in DNA Recognition

Effect of the B ring and the C-7 substituent on the kinetics of colchicinoid-tubulin associations

Matrix interference from Fc-Fc interactions in immunoassays for detecting human IgG4 therapeutics

Conformational analysis of colchicinoids containing an electron-deficient aromatic ring on the B ring

Effect of B-ring substituents on absorption and circular dichroic spectra of colchicine analogs

Role of the B-ring substituent in the fluorescence of colchicinoid-tubulin and allocolchicinoid-tubulin complexes

Kinetic and spectral properties of colchicine B-ring analogs binding to tubulin

The interaction of land-use history and tree species diversity in driving variation in the aboveground biomass of urban versus non-urban tropical forests

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