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CLC Chloride Channels and Transporters: Structure, Function, Physiology, and Disease

Physiological reviews, 2018-07, Vol.98 (3), p.1493-1590

2018

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Subunit‐dependent oxidative stress sensitivity of LRRC8 volume‐regulated anion channels

The Journal of physiology, 2017-11, Vol.595 (21), p.6719-6733

2017

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Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5

Nature, 2005-07, Vol.436 (7049), p.420-423

2005

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An Up-to-Date Overview of the Complexity of Genotype-Phenotype Relationships in Myotonic Channelopathies

Frontiers in neurology, 2020-01, Vol.10, p.1404-1404

2020

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The human two-pore channel 1 is modulated by cytosolic and luminal calcium

Scientific reports, 2017-03, Vol.7 (1), p.43900-43900, Article 43900

2017

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Oxidative Stress and Immune Response in Melanoma: Ion Channels as Targets of Therapy

International journal of molecular sciences, 2023-01, Vol.24 (1), p.887

2023

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d‐Galactose induced early aging in human erythrocytes: Role of band 3 protein

Journal of cellular physiology, 2022-02, Vol.237 (2), p.1586-1596

2022

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Conversion of the 2 Cl−/1 H+ antiporter ClC-5 in a NO3−/H+ antiporter by a single point mutation

The EMBO journal, 2009-02, Vol.28 (3), p.175-182

2009

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The VRAC blocker DCPIB directly gates the BK channels and increases intracellular Ca2+ in melanoma and pancreatic duct adenocarcinoma cell lines

British journal of pharmacology, 2022-07, Vol.179 (13), p.3452-3469

2022

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ClC-5: Physiological role and biophysical mechanisms

Cell calcium (Edinburgh), 2015-07, Vol.58 (1), p.57-66

2015

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IK Channel-Independent Effects of Clotrimazole and Senicapoc on Cancer Cells Viability and Migration

International journal of molecular sciences, 2023-11, Vol.24 (22), p.16285

2023

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BK Channel in the Physiology and in the Cancer of Pancreatic Duct: Impact and Reliability of BK Openers

Frontiers in pharmacology, 2022-05, Vol.13, p.906608-906608

2022

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TRPM2 Oxidation Activates Two Distinct Potassium Channels in Melanoma Cells through Intracellular Calcium Increase

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8359

2021

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Structure of the human ClC-1 chloride channel

PLoS biology, 2019-04, Vol.17 (4), p.e3000218-e3000218

2019

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Is Neuronal Fatigue the Cause of Migraine?

Brain sciences, 2022-05, Vol.12 (5), p.673

2022

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Mechanisms of Activation of LRRC8 Volume Regulated Anion Channels

Cellular physiology and biochemistry, 2021-02, Vol.55 (S1), p.41-56

2021

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Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine

The Lancet (British edition), 2005-07, Vol.366 (9483), p.371-377

2005

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ClC-1 Chloride Channel: Inputs on the Structure–Function Relationship of Myotonia Congenita-Causing Mutations

Biomedicines, 2023-09, Vol.11 (10), p.2622

2023

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Arginine-selective modulation of the lysosomal transporter PQLC2 through a gate-tuning mechanism

Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (32), p.1

2021

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Voltage-Gated Sodium Channel Dysfunctions in Neurological Disorders

Life (Basel, Switzerland), 2023-05, Vol.13 (5), p.1191

2023

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Small Molecules Targeting Kidney ClC-K Chloride Channels: Applications in Rare Tubulopathies and Common Cardiovascular Diseases

Biomolecules (Basel, Switzerland), 2023-04, Vol.13 (4), p.710

2023

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NS-11021 Modulates Cancer-Associated Processes Independently of BK Channels in Melanoma and Pancreatic Duct Adenocarcinoma Cell Lines

Cancers, 2021-12, Vol.13 (23), p.6144

2021

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Molecular Determinants of KCNQ (Kv7) K+ Channel Sensitivity to the Anticonvulsant Retigabine

The Journal of neuroscience, 2005-05, Vol.25 (20), p.5051-5060

2005

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Biophysical Aspects of Neurodegenerative and Neurodevelopmental Disorders Involving Endo-/Lysosomal CLC Cl - /H + Antiporters

Life (Basel, Switzerland), 2023-06, Vol.13 (6), p.1317

2023

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Ion Channel Involvement in Tumor Drug Resistance

Journal of personalized medicine, 2022-02, Vol.12 (2), p.210

2022

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CLC Chloride Channels and Transporters: Structure, Function, Physiology, and Disease

Subunit‐dependent oxidative stress sensitivity of LRRC8 volume‐regulated anion channels

Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5

An Up-to-Date Overview of the Complexity of Genotype-Phenotype Relationships in Myotonic Channelopathies

The human two-pore channel 1 is modulated by cytosolic and luminal calcium

Oxidative Stress and Immune Response in Melanoma: Ion Channels as Targets of Therapy

d‐Galactose induced early aging in human erythrocytes: Role of band 3 protein

Conversion of the 2 Cl−/1 H+ antiporter ClC-5 in a NO3−/H+ antiporter by a single point mutation

The VRAC blocker DCPIB directly gates the BK channels and increases intracellular Ca2+ in melanoma and pancreatic duct adenocarcinoma cell lines

ClC-5: Physiological role and biophysical mechanisms

IK Channel-Independent Effects of Clotrimazole and Senicapoc on Cancer Cells Viability and Migration

BK Channel in the Physiology and in the Cancer of Pancreatic Duct: Impact and Reliability of BK Openers

TRPM2 Oxidation Activates Two Distinct Potassium Channels in Melanoma Cells through Intracellular Calcium Increase

Structure of the human ClC-1 chloride channel

Is Neuronal Fatigue the Cause of Migraine?

Mechanisms of Activation of LRRC8 Volume Regulated Anion Channels

Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine

ClC-1 Chloride Channel: Inputs on the Structure–Function Relationship of Myotonia Congenita-Causing Mutations

Arginine-selective modulation of the lysosomal transporter PQLC2 through a gate-tuning mechanism

Voltage-Gated Sodium Channel Dysfunctions in Neurological Disorders

Small Molecules Targeting Kidney ClC-K Chloride Channels: Applications in Rare Tubulopathies and Common Cardiovascular Diseases

NS-11021 Modulates Cancer-Associated Processes Independently of BK Channels in Melanoma and Pancreatic Duct Adenocarcinoma Cell Lines

Molecular Determinants of KCNQ (Kv7) K+ Channel Sensitivity to the Anticonvulsant Retigabine

Biophysical Aspects of Neurodegenerative and Neurodevelopmental Disorders Involving Endo-/Lysosomal CLC Cl - /H + Antiporters

Ion Channel Involvement in Tumor Drug Resistance

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