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Computational modeling studies reveal the origin of the binding preference of 3‐(3,4‐di hydroisoquinolin‐2(1H)‐ylsulfonyl)benzoic acids for AKR1C3 over its isoforms

Protein science, 2022-12, Vol.31 (12), p.e4499-n/a

2022

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Multi-targeted therapy of cancer by niclosamide: A new application for an old drug

Cancer letters, 2014-07, Vol.349 (1), p.8-14

2014

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STAT3 Is Necessary for Proliferation and Survival in Colon Cancer―Initiating Cells

Cancer research (Chicago, Ill.), 2011-12, Vol.71 (23), p.7226-7237

2011

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Protective effect of suppressing STAT3 activity in LPS-induced acute lung injury

American journal of physiology. Lung cellular and molecular physiology, 2016-11, Vol.311 (5), p.L868-L880

2016

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BET Bromodomain Inhibitors: Novel Design Strategies and Therapeutic Applications

Molecules (Basel, Switzerland), 2023-03, Vol.28 (7), p.3043

2023

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Inhibition of STAT3 Signaling Blocks the Anti-apoptotic Activity of IL-6 in Human Liver Cancer Cells

The Journal of biological chemistry, 2010-08, Vol.285 (35), p.27429-27439

2010

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JAK-STAT Blockade Inhibits Tumor Initiation and Clonogenic Recovery of Prostate Cancer Stem-like Cells

Cancer research (Chicago, Ill.), 2013-08, Vol.73 (16), p.5288-5298

2013

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Novel STAT3 Phosphorylation Inhibitors Exhibit Potent Growth-Suppressive Activity in Pancreatic and Breast Cancer Cells

Cancer research (Chicago, Ill.), 2010-03, Vol.70 (6), p.2445-2454

2010

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Constitutively Active Androgen Receptor in Hepatocellular Carcinoma

International journal of molecular sciences, 2022-11, Vol.23 (22), p.13768

2022

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A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells

International journal of cancer, 2012-03, Vol.130 (6), p.1459-1469

2012

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Curcumin is a potent DNA hypomethylation agent

Bioorganic & medicinal chemistry letters, 2009-02, Vol.19 (3), p.706-709

2009

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A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppressive Activity in Human Cancer Cells

Neoplasia (New York, N.Y.), 2010-01, Vol.12 (1), p.39,IN5-50,IN5

2010

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Sorafenib Overcomes TRAIL Resistance of Hepatocellular Carcinoma Cells through the Inhibition of STAT3

Clinical cancer research, 2010-11, Vol.16 (21), p.5189-5199

2010

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First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy

Cancer discovery, 2012-08, Vol.2 (8), p.694-705

2012

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The small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells

PloS one, 2011-04, Vol.6 (4), p.e18820

2011

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Evaluation of STAT3 signaling in ALDH+ and ALDH+/CD44+/CD24- subpopulations of breast cancer cells

PloS one, 2013-12, Vol.8 (12), p.e82821-e82821

2013

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New curcumin analogues exhibit enhanced growth‐suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells

Cancer science, 2009-09, Vol.100 (9), p.1719-1727

2009

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Phosphoproteomic analysis of anaplastic lymphoma kinase (ALK) downstream signaling pathways identifies signal transducer and activator of transcription 3 as a functional target of activated ALK in neuroblastoma cells

The FEBS journal, 2013-11, Vol.280 (21), p.5269-5282

2013

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Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines

PloS one, 2012-08, Vol.7 (8), p.e40724

2012

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A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

Molecular cancer, 2010-08, Vol.9 (1), p.217-217

2010

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Glioma Cell Migration on Three-dimensional Nanofiber Scaffolds Is Regulated by Substrate Topography and Abolished by Inhibition of STAT3 Signaling

Neoplasia (New York, N.Y.), 2011-09, Vol.13 (9), p.831-IN22

2011

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Characterization of STAT3 activation and expression in canine and human osteosarcoma

BMC cancer, 2009-03, Vol.9 (1), p.81-81, Article 81

2009

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Modulation of DNA methylation by a sesquiterpene lactone parthenolide

The Journal of pharmacology and experimental therapeutics, 2009-05, Vol.329 (2), p.505-514

2009

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Rationally Designed ACE2-Derived Peptides Inhibit SARS-CoV‑2

Bioconjugate chemistry, 2021-01, Vol.32 (1), p.215-223

2021

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The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines

BMC cancer, 2011-03, Vol.11 (1), p.112-112, Article 112

2011

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Computational modeling studies reveal the origin of the binding preference of 3‐(3,4‐di hydroisoquinolin‐2(1H)‐ylsulfonyl)benzoic acids for AKR1C3 over its isoforms

Multi-targeted therapy of cancer by niclosamide: A new application for an old drug

STAT3 Is Necessary for Proliferation and Survival in Colon Cancer―Initiating Cells

Protective effect of suppressing STAT3 activity in LPS-induced acute lung injury

BET Bromodomain Inhibitors: Novel Design Strategies and Therapeutic Applications

Inhibition of STAT3 Signaling Blocks the Anti-apoptotic Activity of IL-6 in Human Liver Cancer Cells

JAK-STAT Blockade Inhibits Tumor Initiation and Clonogenic Recovery of Prostate Cancer Stem-like Cells

Novel STAT3 Phosphorylation Inhibitors Exhibit Potent Growth-Suppressive Activity in Pancreatic and Breast Cancer Cells

Constitutively Active Androgen Receptor in Hepatocellular Carcinoma

A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells

Curcumin is a potent DNA hypomethylation agent

A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppressive Activity in Human Cancer Cells

Sorafenib Overcomes TRAIL Resistance of Hepatocellular Carcinoma Cells through the Inhibition of STAT3

First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy

The small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells

Evaluation of STAT3 signaling in ALDH+ and ALDH+/CD44+/CD24- subpopulations of breast cancer cells

New curcumin analogues exhibit enhanced growth‐suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells

Phosphoproteomic analysis of anaplastic lymphoma kinase (ALK) downstream signaling pathways identifies signal transducer and activator of transcription 3 as a functional target of activated ALK in neuroblastoma cells

Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines

A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

Glioma Cell Migration on Three-dimensional Nanofiber Scaffolds Is Regulated by Substrate Topography and Abolished by Inhibition of STAT3 Signaling

Characterization of STAT3 activation and expression in canine and human osteosarcoma

Modulation of DNA methylation by a sesquiterpene lactone parthenolide

Rationally Designed ACE2-Derived Peptides Inhibit SARS-CoV‑2

The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines

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