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TMEM16A Inhibitors Reveal TMEM16A as a Minor Component of Calcium-activated Chloride Channel Conductance in Airway and Intestinal Epithelial Cells

The Journal of biological chemistry, 2011-01, Vol.286 (3), p.2365-2374

2011

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Anti-Aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica

Annals of neurology, 2012-03, Vol.71 (3), p.314-322

2012

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The aquaporin-4 water channel as a potential drug target in neurological disorders

Expert opinion on therapeutic targets, 2017-12, Vol.21 (12), p.1161-1170

2017

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Affinity-matured ‘aquaporumab’ anti-aquaporin-4 antibody for therapy of seropositive neuromyelitis optica spectrum disorders

Neuropharmacology, 2020-01, Vol.162, p.107827-107827, Article 107827

2020

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Biology of AQP4 and Anti-AQP4 Antibody: Therapeutic Implications for NMO

Brain pathology (Zurich, Switzerland), 2013-11, Vol.23 (6), p.684-695

2013

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Benzopyrimido‐pyrrolo‐oxazine‐dione CFTR inhibitor (R)‐BPO‐27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins

The FASEB journal, 2017-02, Vol.31 (2), p.751-760

2017

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Inhibition of Ca²⁺-activated Cl⁻ channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea

The FASEB journal, 2010-11, Vol.24 (11), p.4178-4186

2010

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Nanomolar-potency ‘co-potentiator’ therapy for cystic fibrosis caused by a defined subset of minimal function CFTR mutants

Scientific reports, 2019-11, Vol.9 (1), p.17640-12, Article 17640

2019

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Inhibitors of pendrin anion exchange identified in a small molecule screen increase airway surface liquid volume in cystic fibrosis

The FASEB journal, 2016-06, Vol.30 (6), p.2187-2197

2016

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Small‐molecule inhibitors of NMO‐IgG binding to aquaporin‐4 reduce astrocyte cytotoxicity in neuromyelitis optica

The FASEB journal, 2012-05, Vol.26 (5), p.2197-2208

2012

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Synergy-based small-molecule screen using a human lung epithelial cell line yields ΔF508-CFTR correctors that augment VX-809 maximal efficacy

Molecular pharmacology, 2014-07, Vol.86 (1), p.42-51

2014

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Nanomolar Potency and Metabolically Stable Inhibitors of Kidney Urea Transporter UT-B

Journal of medicinal chemistry, 2012-06, Vol.55 (12), p.5942-5950

2012

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High-Potency Phenylquinoxalinone Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activators

Journal of medicinal chemistry, 2017-03, Vol.60 (6), p.2401-2410

2017

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Potential therapeutic benefit of C1-esterase inhibitor in neuromyelitis optica evaluated in vitro and in an experimental rat model

PloS one, 2014-09, Vol.9 (9), p.e106824

2014

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Bioactive Thymosin Alpha-1 Does Not Influence F508del-CFTR Maturation and Activity

Scientific reports, 2019-07, Vol.9 (1), p.10310-13, Article 10310

2019

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Synthesis and evaluation of tetrahydropyrazolopyridine inhibitors of anion exchange protein SLC26A4 (pendrin)

Bioorganic & medicinal chemistry letters, 2019-08, Vol.29 (16), p.2119-2123

2019

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Diuresis and reduced urinary osmolality in rats produced by small‐molecule UT‐A‐selective urea transport inhibitors

The FASEB journal, 2014-09, Vol.28 (9), p.3878-3890

2014

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Cyanoquinolines with independent corrector and potentiator activities restore ΔPhe508-cystic fibrosis transmembrane conductance regulator chloride channel function in cystic fibrosis

Molecular pharmacology, 2011-10, Vol.80 (4), p.683-693

2011

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Small molecule screen yields inhibitors of pseudomonas homoserine lactone‐induced host responses

Cellular microbiology, 2014-01, Vol.16 (1), p.1-14

2014

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A Priori Theoretical Prediction of Selectivity in Asymmetric Catalysis: Design of Chiral Catalysts by Using Quantum Molecular Interaction Fields

Angewandte Chemie International Edition, 2006-08, Vol.45 (33), p.5502-5505

2006

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Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation

Translational research : the journal of laboratory and clinical medicine, 2017-04, Vol.182, p.14-26.e4

2017

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Complement-dependent Cytotoxicity in Neuromyelitis Optica Requires Aquaporin-4 Protein Assembly in Orthogonal Arrays

The Journal of biological chemistry, 2012-04, Vol.287 (17), p.13829-13839

2012

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Constrained Bithiazoles: Small Molecule Correctors of Defective ΔF508–CFTR Protein Trafficking

Journal of medicinal chemistry, 2014-08, Vol.57 (15), p.6729-6738

2014

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Cell division modulates prion accumulation in cultured cells

Proceedings of the National Academy of Sciences - PNAS, 2007-11, Vol.104 (46), p.17971-17976

2007

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Structure–Activity Relationships of Cyanoquinolines with Corrector–Potentiator Activity in ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator Protein

Journal of medicinal chemistry, 2012-02, Vol.55 (3), p.1242-1251

2012

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TMEM16A Inhibitors Reveal TMEM16A as a Minor Component of Calcium-activated Chloride Channel Conductance in Airway and Intestinal Epithelial Cells

Anti-Aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica

The aquaporin-4 water channel as a potential drug target in neurological disorders

Affinity-matured ‘aquaporumab’ anti-aquaporin-4 antibody for therapy of seropositive neuromyelitis optica spectrum disorders

Biology of AQP4 and Anti-AQP4 Antibody: Therapeutic Implications for NMO

Benzopyrimido‐pyrrolo‐oxazine‐dione CFTR inhibitor (R)‐BPO‐27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins

Inhibition of Ca²⁺-activated Cl⁻ channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea

Nanomolar-potency ‘co-potentiator’ therapy for cystic fibrosis caused by a defined subset of minimal function CFTR mutants

Inhibitors of pendrin anion exchange identified in a small molecule screen increase airway surface liquid volume in cystic fibrosis

Small‐molecule inhibitors of NMO‐IgG binding to aquaporin‐4 reduce astrocyte cytotoxicity in neuromyelitis optica

Synergy-based small-molecule screen using a human lung epithelial cell line yields ΔF508-CFTR correctors that augment VX-809 maximal efficacy

Nanomolar Potency and Metabolically Stable Inhibitors of Kidney Urea Transporter UT-B

High-Potency Phenylquinoxalinone Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activators

Potential therapeutic benefit of C1-esterase inhibitor in neuromyelitis optica evaluated in vitro and in an experimental rat model

Bioactive Thymosin Alpha-1 Does Not Influence F508del-CFTR Maturation and Activity

Synthesis and evaluation of tetrahydropyrazolopyridine inhibitors of anion exchange protein SLC26A4 (pendrin)

Diuresis and reduced urinary osmolality in rats produced by small‐molecule UT‐A‐selective urea transport inhibitors

Cyanoquinolines with independent corrector and potentiator activities restore ΔPhe508-cystic fibrosis transmembrane conductance regulator chloride channel function in cystic fibrosis

Small molecule screen yields inhibitors of pseudomonas homoserine lactone‐induced host responses

A Priori Theoretical Prediction of Selectivity in Asymmetric Catalysis: Design of Chiral Catalysts by Using Quantum Molecular Interaction Fields

Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation

Complement-dependent Cytotoxicity in Neuromyelitis Optica Requires Aquaporin-4 Protein Assembly in Orthogonal Arrays

Constrained Bithiazoles: Small Molecule Correctors of Defective ΔF508–CFTR Protein Trafficking

Cell division modulates prion accumulation in cultured cells

Structure–Activity Relationships of Cyanoquinolines with Corrector–Potentiator Activity in ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator Protein

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