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Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases

Molecular cell, 2012-09, Vol.47 (6), p.933-942

2012

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Bacteria make surgical strikes on host ubiquitin signaling

PLoS pathogens, 2021-03, Vol.17 (3), p.e1009341-e1009341

2021

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The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases

Molecular cell, 2016-07, Vol.63 (2), p.261-276

2016

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Bacterial usurpation of the OTU deubiquitinase fold

The FEBS journal, 2024-08, Vol.291 (15), p.3303-3316

2024

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Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin

Molecular cell, 2015-04, Vol.58 (1), p.95-109

2015

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Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis

The EMBO journal, 2015-02, Vol.34 (3), p.307-325

2015

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Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal

Nature (London), 2015-01, Vol.517 (7533), p.223-226

2015

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Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA

Molecular cell, 2023-01, Vol.83 (1), p.105-120.e5

2023

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Identification and characterization of diverse OTU deubiquitinases in bacteria

The EMBO journal, 2020-08, Vol.39 (15), p.e105127-n/a

2020

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OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function

Molecular cell, 2012-02, Vol.45 (3), p.384-397

2012

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A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes

Nature chemical biology, 2016-07, Vol.12 (7), p.523-530

2016

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Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (14), p.5287-5287

2013

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A High-Throughput Assay for Monitoring Ubiquitination in Real Time

Frontiers in chemistry, 2019-12, Vol.7, p.816-816

2019

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Ubiquitin in Motion: Structural Studies of the Ubiquitin-Conjugating Enzyme∼Ubiquitin Conjugate

Biochemistry (Easton), 2011-03, Vol.50 (10), p.1624-1633

2011

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The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation

eLife, 2024-02, Vol.12

2024

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Ubiquitylation: Sword and shield in the bacterial arsenal

Molecular cell, 2024-09, Vol.84 (18), p.3378-3380

2024

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Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays

eLife, 2023-12, Vol.12

2023

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A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation

Nature microbiology, 2018-12, Vol.3 (12), p.1377-1384

2018

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RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination

Biochimica et biophysica acta, 2014-01, Vol.1843 (1), p.47

2014

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Evaluating enzyme activities and structures of DUBs

Methods in enzymology, 2019, Vol.618, p.321-341

2019

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Bacterial lipids earmarked with ubiquitin for pathogen clearance

Molecular cell, 2021-07, Vol.81 (13), p.2690-2692

2021

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Insights into ubiquitin chain architecture using Ub-clipping

Nature (London), 2019-08, Vol.572 (7770), p.533-537

2019

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Ubiquitin-targeted bacterial effectors: rule breakers of the ubiquitin system

The EMBO journal, 2023-09, Vol.42 (18), p.e114318

2023

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Interplay between septins and ubiquitin-mediated xenophagy during Shigella entrapment

Autophagy reports, 2023-01, Vol.2 (1)

2023

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Bacterial ligases reveal fundamental principles of polyubiquitin specificity

Molecular cell, 2023-12, Vol.83 (24), p.4538-4554.e4

2023

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Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases

Bacteria make surgical strikes on host ubiquitin signaling

The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases

Bacterial usurpation of the OTU deubiquitinase fold

Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin

Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis

Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal

Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA

Identification and characterization of diverse OTU deubiquitinases in bacteria

OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function

A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes

Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis

A High-Throughput Assay for Monitoring Ubiquitination in Real Time

Ubiquitin in Motion: Structural Studies of the Ubiquitin-Conjugating Enzyme∼Ubiquitin Conjugate

The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation

Ubiquitylation: Sword and shield in the bacterial arsenal

Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays

A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation

RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination

Evaluating enzyme activities and structures of DUBs

Bacterial lipids earmarked with ubiquitin for pathogen clearance

Insights into ubiquitin chain architecture using Ub-clipping

Ubiquitin-targeted bacterial effectors: rule breakers of the ubiquitin system

Interplay between septins and ubiquitin-mediated xenophagy during Shigella entrapment

Bacterial ligases reveal fundamental principles of polyubiquitin specificity

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