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Whole-sporozoite malaria vaccines: where we are, where we are going

EMBO molecular medicine, 2024-09, Vol.16 (10), p.2279-2289

2024

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A new malaria vaccination tool based on replication-competent Plasmodium falciparum parasites

EMBO molecular medicine, 2024-04, Vol.16 (4), p.667-669

2024

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Molecular Design and Synthesis of Ivermectin Hybrids Targeting Hepatic and Erythrocytic Stages of Plasmodium Parasites

Journal of medicinal chemistry, 2020-02, Vol.63 (4), p.1750-1762

2020

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Repurposing Drugs to Fight Hepatic Malaria Parasites

Molecules (Basel, Switzerland), 2020-07, Vol.25 (15), p.3409

2020

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Five decades of clinical assessment of whole-sporozoite malaria vaccines

Frontiers in immunology, 2022-09, Vol.13, p.977472-977472

2022

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The silent path to thousands of merozoites: the Plasmodium liver stage

Nature reviews. Microbiology, 2006-11, Vol.4 (11), p.849-856

2006

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Liver-stage malaria parasites vulnerable to diverse chemical scaffolds

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (22), p.8511-8516

2012

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Targeting the Liver Stage of Malaria Parasites: A Yet Unmet Goal

Journal of medicinal chemistry, 2012-02, Vol.55 (3), p.995-1012

2012

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Maria M. Mota: Bringing Plasmodium Liver Infection to the Centre Stage of Malaria Research

Frontiers in cellular and infection microbiology, 2022-02, Vol.12, p.851484-851484

2022

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Inhibition of Plasmodium sporogonic stages by ivermectin and other avermectins

Parasites & vectors, 2019-11, Vol.12 (1), p.549-549, Article 549

2019

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Novel harmicines with improved potency against plasmodium

Molecules (Basel, Switzerland), 2020-09, Vol.25 (19), p.4376

2020

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In Fairness to Mosquitoes

Trends in parasitology, 2020-11, Vol.36 (11), p.876-877

Prudêncio, Miguel

2020

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Half-Sandwich Cyclopentadienylruthenium(II) Complexes: A New Antimalarial Chemotype

Inorganic chemistry, 2020-09, Vol.59 (17), p.12722-12732

2020

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N‑Cinnamoylated Chloroquine Analogues as Dual-Stage Antimalarial Leads

Journal of medicinal chemistry, 2013-01, Vol.56 (2), p.556-567

2013

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Antimalarial Pyrido[1,2‑a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model

Journal of medicinal chemistry, 2017-02, Vol.60 (4), p.1432-1448

2017

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The impact of antiretroviral therapy on malaria parasite transmission

Frontiers in microbiology, 2020-01, Vol.10, p.3048-3048

2020

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Portugal’s prominence in malaria research

EMBO reports, 2021-02, Vol.22 (2), p.n/a

Prudêncio, Miguel

2021

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Primaquine-based ionic liquids as a novel class of antimalarial hits

RSC advances, 2016, Vol.6 (61), p.56134-56138

2016

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Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside

Malaria journal, 2022-05, Vol.21 (1), p.151-151, Article 151

2022

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Portugal’s prominence in malaria research: How a small country became a key player in European research on one of the world’s deadliest diseases

EMBO reports, 2021-02, Vol.22 (2), p.e51692-e51692

Prudêncio, Miguel

2021

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Trypanosoma brucei infection protects mice against malaria

PLoS pathogens, 2019-11, Vol.15 (11), p.e1008145-e1008145

2019

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Structure–Activity Relationship Studies and Plasmodium Life Cycle Profiling Identifies Pan-Active N‑Aryl-3-trifluoromethyl Pyrido[1,2‑a]benzimidazoles Which Are Efficacious in an in Vivo Mouse Model of Malaria

Journal of medicinal chemistry, 2019-01, Vol.62 (2), p.1022-1035

2019

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Tetraoxane–Pyrimidine Nitrile Hybrids as Dual Stage Antimalarials

Journal of medicinal chemistry, 2014-06, Vol.57 (11), p.4916-4923

2014

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Impact of Dietary Protein Restriction on the Immunogenicity and Efficacy of Whole-Sporozoite Malaria Vaccination

Frontiers in immunology, 2022-04, Vol.13, p.869757-869757

2022

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Whole-sporozoite malaria vaccines: where we are, where we are going

A new malaria vaccination tool based on replication-competent Plasmodium falciparum parasites

Molecular Design and Synthesis of Ivermectin Hybrids Targeting Hepatic and Erythrocytic Stages of Plasmodium Parasites

Repurposing Drugs to Fight Hepatic Malaria Parasites

Five decades of clinical assessment of whole-sporozoite malaria vaccines

The silent path to thousands of merozoites: the Plasmodium liver stage

Liver-stage malaria parasites vulnerable to diverse chemical scaffolds

Targeting the Liver Stage of Malaria Parasites: A Yet Unmet Goal

Maria M. Mota: Bringing Plasmodium Liver Infection to the Centre Stage of Malaria Research

Inhibition of Plasmodium sporogonic stages by ivermectin and other avermectins

Novel harmicines with improved potency against plasmodium

In Fairness to Mosquitoes

Half-Sandwich Cyclopentadienylruthenium(II) Complexes: A New Antimalarial Chemotype

N‑Cinnamoylated Chloroquine Analogues as Dual-Stage Antimalarial Leads

Antimalarial Pyrido[1,2‑a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model

The impact of antiretroviral therapy on malaria parasite transmission

Portugal’s prominence in malaria research

Primaquine-based ionic liquids as a novel class of antimalarial hits

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside

Portugal’s prominence in malaria research: How a small country became a key player in European research on one of the world’s deadliest diseases

Trypanosoma brucei infection protects mice against malaria

Structure–Activity Relationship Studies and Plasmodium Life Cycle Profiling Identifies Pan-Active N‑Aryl-3-trifluoromethyl Pyrido[1,2‑a]benzimidazoles Which Are Efficacious in an in Vivo Mouse Model of Malaria

Tetraoxane–Pyrimidine Nitrile Hybrids as Dual Stage Antimalarials

Impact of Dietary Protein Restriction on the Immunogenicity and Efficacy of Whole-Sporozoite Malaria Vaccination

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