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Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide

Breast cancer research : BCR, 2014-01, Vol.16 (1), p.R7-R7, Article R7

2014

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Evidence for Functional Heterogeneity of Circulating B-Type Natriuretic Peptide

Journal of the American College of Cardiology, 2007-03, Vol.49 (10), p.1071-1078

2007

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Restricted Delivery of Talazoparib Across the Blood-Brain Barrier Limits the Sensitizing Effects of PARP Inhibition on Temozolomide Therapy in Glioblastoma

Molecular cancer therapeutics, 2017-12, Vol.16 (12), p.2735-2746

2017

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Elucidating host cell response pathways and repurposing therapeutics for SARS-CoV-2 and other coronaviruses

Scientific reports, 2022-11, Vol.12 (1), p.18811-11, Article 18811

2022

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Enzalutamide, an androgen receptor signaling inhibitor, induces tumor regression in a mouse model of castration-resistant prostate cancer

The Prostate, 2013-09, Vol.73 (12), p.1291-1305

2013

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Recombinant Vascular Endothelial Growth Factor 121 Attenuates Hypertension and Improves Kidney Damage in a Rat Model of Preeclampsia

Hypertension (Dallas, Tex. 1979), 2007-10, Vol.50 (4), p.686-692

2007

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Activation of p38 mitogen‐activated protein kinase in spinal microglia is a critical link in inflammation‐induced spinal pain processing

Journal of neurochemistry, 2003-09, Vol.86 (6), p.1534-1544

2003

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Progressive transforming growth factor β1-induced lung fibrosis is blocked by an orally active alk5 kinase inhibitor

American journal of respiratory and critical care medicine, 2005-04, Vol.171 (8), p.889-898

2005

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The precursor to B-type natriuretic peptide is an O-linked glycoprotein

Archives of biochemistry and biophysics, 2006-07, Vol.451 (2), p.160-166

2006

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Detection of endogenous B-type natriuretic peptide at very low concentrations in patients with heart failure

Circulation. Heart failure, 2008-11, Vol.1 (4), p.258-264

2008

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B-Type Natriuretic Peptide Exerts Broad Functional Opposition to Transforming Growth Factor-β in Primary Human Cardiac Fibroblasts: Fibrosis, Myofibroblast Conversion, Proliferation, and Inflammation

Circulation research, 2004-03, Vol.94 (4), p.453-461

2004

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Altered Patterns of Gene Expression in Response to Myocardial Infarction

Circulation research, 2000-05, Vol.86 (9), p.939-945

2000

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Temozolomide analogs with improved brain/plasma ratios – Exploring the possibility of enhancing the therapeutic index of temozolomide

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (20), p.5103-5109

2016

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Cognition-enhancing properties of Dimebon in a rat novel object recognition task are unlikely to be associated with acetylcholinesterase inhibition or N-methyl-D-aspartate receptor antagonism

The Journal of pharmacology and experimental therapeutics, 2010-06, Vol.333 (3), p.748-757

2010

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Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE2 release and thermal hyperalgesia

Neuroreport, 2003-06, Vol.14 (8), p.1153-1157

2003

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Discovery of pyrazolopyrimidine derivatives as novel inhibitors of ataxia telangiectasia and rad3 related protein (ATR)

Bioorganic & medicinal chemistry letters, 2017-02, Vol.27 (4), p.750-754

2017

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Transforming Growth Factor-β Blockade Down-Regulates the Renin-Angiotensin System and Modifies Cardiac Remodeling after Myocardial Infarction

Endocrinology (Philadelphia), 2008-11, Vol.149 (11), p.5828-5834

2008

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A p38 Mitogen‐Activated Protein Kinase Inhibitor Arrests Active Alveolar Bone Loss in a Rat Periodontitis Model

Journal of periodontology (1970), 2007-10, Vol.78 (10), p.1992-1998

2007

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Inhibiting TGF-beta signaling restores immune surveillance in the SMA-560 glioma model

Neuro-oncology (Charlottesville, Va.), 2007-07, Vol.9 (3), p.259-270

2007

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Effect of transforming growth factor-beta receptor I kinase inhibitor 2,4-disubstituted pteridine (SD-208) in chronic allergic airway inflammation and remodeling

The Journal of pharmacology and experimental therapeutics, 2006-11, Vol.319 (2), p.586-594

2006

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B-Type Natriuretic Peptide Inhibited Angiotensin II-Stimulated Cholesterol Biosynthesis, Cholesterol Transfer, and Steroidogenesis in Primary Human Adrenocortical Cells

Endocrinology (Philadelphia), 2007-08, Vol.148 (8), p.3722-3729

2007

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A selective p38 alpha mitogen-activated protein kinase inhibitor reverses cartilage and bone destruction in mice with collagen-induced arthritis

The Journal of pharmacology and experimental therapeutics, 2006-07, Vol.318 (1), p.132-141

2006

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Antitumor Activity of TGF-β Inhibitor is Dependent on the Microenvironment

Anticancer research, 2007-11, Vol.27 (6B), p.4149-4157

2007

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Transforming Growth Factor-β Receptor Type 1 (TGFβRI) Kinase Activity but Not p38 Activation Is Required for TGFβRI-Induced Myofibroblast Differentiation and Profibrotic Gene Expression

Molecular pharmacology, 2006-08, Vol.70 (2), p.518-531

2006

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Clinical Implications of Defective B‐Type Natriuretic Peptide

Clinical cardiology (Mahwah, N.J.), 2009-12, Vol.32 (12), p.E36-E41

2009

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Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide

Evidence for Functional Heterogeneity of Circulating B-Type Natriuretic Peptide

Restricted Delivery of Talazoparib Across the Blood-Brain Barrier Limits the Sensitizing Effects of PARP Inhibition on Temozolomide Therapy in Glioblastoma

Elucidating host cell response pathways and repurposing therapeutics for SARS-CoV-2 and other coronaviruses

Enzalutamide, an androgen receptor signaling inhibitor, induces tumor regression in a mouse model of castration-resistant prostate cancer

Recombinant Vascular Endothelial Growth Factor 121 Attenuates Hypertension and Improves Kidney Damage in a Rat Model of Preeclampsia

Activation of p38 mitogen‐activated protein kinase in spinal microglia is a critical link in inflammation‐induced spinal pain processing

Progressive transforming growth factor β1-induced lung fibrosis is blocked by an orally active alk5 kinase inhibitor

The precursor to B-type natriuretic peptide is an O-linked glycoprotein

Detection of endogenous B-type natriuretic peptide at very low concentrations in patients with heart failure

B-Type Natriuretic Peptide Exerts Broad Functional Opposition to Transforming Growth Factor-β in Primary Human Cardiac Fibroblasts: Fibrosis, Myofibroblast Conversion, Proliferation, and Inflammation

Altered Patterns of Gene Expression in Response to Myocardial Infarction

Temozolomide analogs with improved brain/plasma ratios – Exploring the possibility of enhancing the therapeutic index of temozolomide

Cognition-enhancing properties of Dimebon in a rat novel object recognition task are unlikely to be associated with acetylcholinesterase inhibition or N-methyl-D-aspartate receptor antagonism

Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE2 release and thermal hyperalgesia

Discovery of pyrazolopyrimidine derivatives as novel inhibitors of ataxia telangiectasia and rad3 related protein (ATR)

Transforming Growth Factor-β Blockade Down-Regulates the Renin-Angiotensin System and Modifies Cardiac Remodeling after Myocardial Infarction

A p38 Mitogen‐Activated Protein Kinase Inhibitor Arrests Active Alveolar Bone Loss in a Rat Periodontitis Model

Inhibiting TGF-beta signaling restores immune surveillance in the SMA-560 glioma model

Effect of transforming growth factor-beta receptor I kinase inhibitor 2,4-disubstituted pteridine (SD-208) in chronic allergic airway inflammation and remodeling

B-Type Natriuretic Peptide Inhibited Angiotensin II-Stimulated Cholesterol Biosynthesis, Cholesterol Transfer, and Steroidogenesis in Primary Human Adrenocortical Cells

A selective p38 alpha mitogen-activated protein kinase inhibitor reverses cartilage and bone destruction in mice with collagen-induced arthritis

Antitumor Activity of TGF-β Inhibitor is Dependent on the Microenvironment

Transforming Growth Factor-β Receptor Type 1 (TGFβRI) Kinase Activity but Not p38 Activation Is Required for TGFβRI-Induced Myofibroblast Differentiation and Profibrotic Gene Expression

Clinical Implications of Defective B‐Type Natriuretic Peptide

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