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Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin

Molecular therapy. Methods & clinical development, 2015-01, Vol.2, p.15040-15040, Article 15040

2015

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Screening for antiviral inhibitors of the HIV integrase-LEDGF/p75 interaction using the AlphaScreen luminescent proximity assay

Journal of biomolecular screening, 2008-06, Vol.13 (5), p.406-414

2008

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Crystal structure of dimeric HIV-1 capsid protein

Nature structural & molecular biology, 1996-09, Vol.3 (9), p.763-770

1996

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Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

Nature structural biology, 1999-03, Vol.6 (3), p.233-242

1999

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Discovery of the HCV NS3/4A Protease Inhibitor (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key Steps in Structure-Based Optimization

Journal of medicinal chemistry, 2007-05, Vol.50 (10), p.2310-2318

2007

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Thermodynamics of Nucleotide and Inhibitor Binding to Wild-Type and Ispinesib-Resistant Forms of Human Kinesin Spindle Protein

Biochemistry (Easton), 2009-11, Vol.48 (46), p.11045-11055

2009

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Design and Synthesis of Depeptidized Macrocyclic Inhibitors of Hepatitis C NS3-4A Protease Using Structure-Based Drug Design

Journal of medicinal chemistry, 2005-08, Vol.48 (16), p.5088-5091

2005

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Novel inhibitors of hepatitis C NS3–NS4A serine protease derived from 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (6), p.1628-1632

2006

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Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034

Journal of synchrotron radiation, 2008-05, Vol.15 (3), p.204-207

2008

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Towards the Determination of the Structure of HIV-1 p24: A Possible Target for Antiviral Therapy

American journal of pharmaceutical education, 1991, Vol.55 (4), p.391-394

Prongay, Andrew J

1991

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PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASES - OVERVIEW OF THE FAMILY AND SOME PROPERTIES OF THIOREDOXIN REDUCTASE ALTERED BY SITE DIRECTED MUTAGENESIS: C135S AND C138S

Flavins and Flavoproteins 1990, 2019, p.497-504

2019

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Site-directed mutagenesis of thioredoxin reductase

Flavins and Flavoproteins 1987, 2019, p.107-110

Originally published 1987, 2019

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Oxidation-reduction properties of Escherichia coli thioredoxin reductase altered at each active site cysteine residue

The Journal of biological chemistry, 1992-12, Vol.267 (35), p.25181-25188

1992

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Preparation and Crystallization of a Human Immunodeficiency Virus p24-Fab Complex

Proceedings of the National Academy of Sciences - PNAS, 1990-12, Vol.87 (24), p.9980-9984

1990

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Additions and Corrections

The Journal of biological chemistry, 1989-07, Vol.264 (20), p.12113-12113

1989

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Properties of Lipoamide Dehydrogenase and Thioredoxin Reductase from Escherichia coli Altered by Site-Directed Mutagenesis

Annals of the New York Academy of Sciences, 1989, Vol.573 (1), p.55-65

1989

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Novel Inhibitors of Hepatitis C NS3-NS4A Serine Protease Derived from 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic Acid

ChemInform, 2006-05, Vol.37 (22), p.no-no

2006

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Properties of Lipoamide Dehydrogenase and Thioredoxin Reductase from Escherichia coli Altered by Site‐Directed Mutagenesisa

Annals of the New York Academy of Sciences, 1989-12, Vol.573 (1), p.55-65

1989

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Reduced infant rhesus macaque growth rates due to environmental enteric dysfunction and association with histopathology in the large intestine

Nature communications, 2022-01, Vol.13 (1), p.234-234, Article 234

2022

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Campylobacter vaccination reduces diarrheal disease and infant growth stunting among rhesus macaques

Nature communications, 2023-06, Vol.14 (1), p.3806-3806, Article 3806

2023

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Standard growth and diarrhea‐associated growth faltering in captive infant rhesus macaques (Macaca mulatta)

American journal of primatology, 2018-09, Vol.80 (9), p.e22923-n/a

2018

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Infant diarrheal disease in rhesus macaques impedes microbiome maturation and is linked to uncultured Campylobacter species

Communications biology, 2024-01, Vol.7 (1), p.37-37, Article 37

2024

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Cerebral cysts of ependymal or ventricular origin in a juvenile rhesus macaque (Macaca mulatta) with neurologic signs

Journal of medical primatology, 2019-12, Vol.48 (6), p.378-380

2019

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Impact of Naturally Occurring Variants of HCV Protease on the Binding of Different Classes of Protease Inhibitors

Biochemistry (Easton), 2006-02, Vol.45 (5), p.1353-1361

2006

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Potent 7-Hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid-Based Macrocyclic Inhibitors of Hepatitis C Virus NS3 Protease

Journal of medicinal chemistry, 2006-01, Vol.49 (2), p.567-574

2006

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Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin

Screening for antiviral inhibitors of the HIV integrase-LEDGF/p75 interaction using the AlphaScreen luminescent proximity assay

Crystal structure of dimeric HIV-1 capsid protein

Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

Discovery of the HCV NS3/4A Protease Inhibitor (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key Steps in Structure-Based Optimization

Thermodynamics of Nucleotide and Inhibitor Binding to Wild-Type and Ispinesib-Resistant Forms of Human Kinesin Spindle Protein

Design and Synthesis of Depeptidized Macrocyclic Inhibitors of Hepatitis C NS3-4A Protease Using Structure-Based Drug Design

Novel inhibitors of hepatitis C NS3–NS4A serine protease derived from 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid

Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034

Towards the Determination of the Structure of HIV-1 p24: A Possible Target for Antiviral Therapy

PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASES - OVERVIEW OF THE FAMILY AND SOME PROPERTIES OF THIOREDOXIN REDUCTASE ALTERED BY SITE DIRECTED MUTAGENESIS: C135S AND C138S

Site-directed mutagenesis of thioredoxin reductase

Oxidation-reduction properties of Escherichia coli thioredoxin reductase altered at each active site cysteine residue

Preparation and Crystallization of a Human Immunodeficiency Virus p24-Fab Complex

Additions and Corrections

Properties of Lipoamide Dehydrogenase and Thioredoxin Reductase from Escherichia coli Altered by Site-Directed Mutagenesis

Novel Inhibitors of Hepatitis C NS3-NS4A Serine Protease Derived from 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic Acid

Properties of Lipoamide Dehydrogenase and Thioredoxin Reductase from Escherichia coli Altered by Site‐Directed Mutagenesisa

Reduced infant rhesus macaque growth rates due to environmental enteric dysfunction and association with histopathology in the large intestine

Campylobacter vaccination reduces diarrheal disease and infant growth stunting among rhesus macaques

Standard growth and diarrhea‐associated growth faltering in captive infant rhesus macaques (Macaca mulatta)

Infant diarrheal disease in rhesus macaques impedes microbiome maturation and is linked to uncultured Campylobacter species

Cerebral cysts of ependymal or ventricular origin in a juvenile rhesus macaque (Macaca mulatta) with neurologic signs

Impact of Naturally Occurring Variants of HCV Protease on the Binding of Different Classes of Protease Inhibitors

Potent 7-Hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid-Based Macrocyclic Inhibitors of Hepatitis C Virus NS3 Protease

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