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Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging

Science (American Association for the Advancement of Science), 2005-07, Vol.309 (5733), p.481-484

2005

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Gene-expression profile of the ageing brain in mice

Nature genetics, 2000-07, Vol.25 (3), p.294-297

2000

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Gene Expression Profile of Aging and Its Retardation by Caloric Restriction

Science (American Association for the Advancement of Science), 1999-08, Vol.285 (5432), p.1390-1393

1999

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Transcriptional Profiles Associated with Aging and Middle Age-Onset Caloric Restriction in Mouse Hearts

Proceedings of the National Academy of Sciences - PNAS, 2002-11, Vol.99 (23), p.14988-14993

2002

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Short-term consumption of a resveratrol-containing nutraceutical mixture mimics gene expression of long-term caloric restriction in mouse heart

Experimental gerontology, 2008-09, Vol.43 (9), p.859-866

2008

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Molecular mechanisms of brain aging and neurodegenerative disorders: lessons from dietary restriction

Trends in Neurosciences, 2001-11, Vol.24 (11), p.S21-S31

2001

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DNA Microarray Analysis of the Aging Brain

Chemical senses, 2002-03, Vol.27 (3), p.299-306

PROLLA, Tomas A

2002

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The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

Free radical biology & medicine, 2003-02, Vol.34 (4), p.496-502

2003

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Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

Nature (London), 1993-09, Vol.365 (6443), p.274-276

1993

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Reduction in Glutathione Peroxidase 4 Increases Life Span Through Increased Sensitivity to Apoptosis

The journals of gerontology. Series A, Biological sciences and medical sciences, 2007-09, Vol.62 (9), p.932-942

2007

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Gene Expression Profiling of Low Selenium Status in the Mouse Intestine: Transcriptional Activation of Genes Linked to DNA Damage, Cell Cycle Control and Oxidative Stress

The Journal of nutrition, 2001-12, Vol.131 (12), p.3175-3181

2001

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Influences of Aging and Caloric Restriction on the Transcriptional Profile of Skeletal Muscle from Rhesus Monkeys

Proceedings of the National Academy of Sciences - PNAS, 2001-04, Vol.98 (9), p.5093-5098

2001

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Lifelong voluntary exercise in the mouse prevents age-related alterations in gene expression in the heart

Physiological genomics, 2003-01, Vol.12 (2), p.129-138

2003

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Gene expression profiling studies of aging in cardiac and skeletal muscles

Cardiovascular research, 2005-05, Vol.66 (2), p.205-212

2005

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THE EVOLUTION OF GENE EXPRESSION IN MOUSE HIPPOCAMPUS IN RESPONSE TO SELECTIVE BREEDING FOR INCREASED LOCOMOTOR ACTIVITY

Evolution, 2004-09, Vol.58 (9), p.2079-2086

2004

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Microarray Profiling of Gene Expression in Aging and Its Alteration by Caloric Restriction in Mice

The Journal of nutrition, 2001-03, Vol.131 (3), p.918S-923S

2001

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MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast

Science (American Association for the Advancement of Science), 1994-08, Vol.265 (5175), p.1091-1093

1994

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Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene

Molecular and Cellular Biology, 1994-01, Vol.14 (1), p.407-415

1994

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Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutations

Molecular and Cellular Biology, 1997-08, Vol.17 (8), p.4465-4473

1997

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Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

Nature genetics, 1996-07, Vol.13 (3), p.336-342

1996

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Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair

Nature genetics, 1998-03, Vol.18 (3), p.276-279

1998

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Ionizing radiation-induced apoptosis via separate Pms2- and p53-dependent pathways

Cancer research (Chicago, Ill.), 2000-09, Vol.60 (17), p.4889-4893

2000

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Somatic Progenitor Cell Vulnerability to Mitochondrial DNA Mutagenesis Underlies Progeroid Phenotypes in Polg Mutator Mice

Cell metabolism, 2012-01, Vol.15 (1), p.100-109

2012

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Role of DNA mismatch repair in the cytotoxicity of ionizing radiation

Cancer research (Chicago, Ill.), 1997-11, Vol.57 (22), p.5143-5147

1997

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Age-related impairment of the transcriptional responses to oxidative stress in the mouse heart

Physiological genomics, 2003-04, Vol.13 (2), p.119-127

2003

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Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging

Gene-expression profile of the ageing brain in mice

Gene Expression Profile of Aging and Its Retardation by Caloric Restriction

Transcriptional Profiles Associated with Aging and Middle Age-Onset Caloric Restriction in Mouse Hearts

Short-term consumption of a resveratrol-containing nutraceutical mixture mimics gene expression of long-term caloric restriction in mouse heart

Molecular mechanisms of brain aging and neurodegenerative disorders: lessons from dietary restriction

DNA Microarray Analysis of the Aging Brain

The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

Reduction in Glutathione Peroxidase 4 Increases Life Span Through Increased Sensitivity to Apoptosis

Gene Expression Profiling of Low Selenium Status in the Mouse Intestine: Transcriptional Activation of Genes Linked to DNA Damage, Cell Cycle Control and Oxidative Stress

Influences of Aging and Caloric Restriction on the Transcriptional Profile of Skeletal Muscle from Rhesus Monkeys

Lifelong voluntary exercise in the mouse prevents age-related alterations in gene expression in the heart

Gene expression profiling studies of aging in cardiac and skeletal muscles

THE EVOLUTION OF GENE EXPRESSION IN MOUSE HIPPOCAMPUS IN RESPONSE TO SELECTIVE BREEDING FOR INCREASED LOCOMOTOR ACTIVITY

Microarray Profiling of Gene Expression in Aging and Its Alteration by Caloric Restriction in Mice

MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene

Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutations

Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair

Ionizing radiation-induced apoptosis via separate Pms2- and p53-dependent pathways

Somatic Progenitor Cell Vulnerability to Mitochondrial DNA Mutagenesis Underlies Progeroid Phenotypes in Polg Mutator Mice

Role of DNA mismatch repair in the cytotoxicity of ionizing radiation

Age-related impairment of the transcriptional responses to oxidative stress in the mouse heart

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