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The effect of rate of drug administration on the extent and time course of phencyclidine distribution in rat brain, testis, and serum

Drug metabolism and disposition, 2000-07, Vol.28 (7), p.742

2000

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SB-242235, a selective inhibitor of p38 mitogen-activated protein kinase. I: Preclinical pharmacokinetics

Xenobiotica, 2002-03, Vol.32 (3), p.221-233

2002

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Preclinical pharmacokinetics of SB-203580, a potent inhibitor of p38 mitogen-activated protein kinase

Xenobiotica, 2001, Vol.31 (11), p.783-797

2001

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SB-242235, a selective inhibitor of p38 mitogen-activated protein kinase. II: In vitro and in vivo metabolism studies and pharmacokinetic extrapolation to man

Xenobiotica, 2002-03, Vol.32 (3), p.235-250

2002

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Anti-phencyclidine monoclonal antibodies provide long-term reductions in brain phencyclidine concentrations during chronic phencyclidine administration in rats

The Journal of pharmacology and experimental therapeutics, 2000-03, Vol.292 (3), p.831

2000

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Effects of lipid A on calcium homeostasis in renal proximal tubules

The Journal of pharmacology and experimental therapeutics, 1996-02, Vol.276 (2), p.555

1996

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Development of an in vivo preclinical screen model to estimate absorption and bioavailability of xenobiotics

Drug metabolism and disposition, 2001-01, Vol.29 (1), p.82

2001

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Nitric oxide generation by renal proximal tubules: role of nitric oxide in the cytotoxicity of lipid A

The Journal of pharmacology and experimental therapeutics, 1996-10, Vol.279 (1), p.91

1996

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A52 PRECLINICAL TRIALS IN PULMONARY HYPERTENSION MODELS: NOVEL TARGETS AND DELIVERY: The Bardoxolone Methyl Analog Rta Dh404 Protects Rats From Monocrotaline-Induced Pulmonary Arterial Hypertension

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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Pharmacokinetics and pharmacodynamics of the novel Nrf2 activator omaveloxolone in primates

Drug design, development and therapy, 2019-01, Vol.13, p.1259-1270

2019

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Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors

OncoTargets and therapy, 2017-01, Vol.10, p.4239-4250

2017

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Pharmacodynamics of a monoclonal antiphencyclidine Fab with broad selectivity for phencyclidine-like drugs

The Journal of pharmacology and experimental therapeutics, 1998-06, Vol.285 (3), p.1113

1998

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SB-239063, a potent and selective inhibitor of p38 map kinase : Preclinical pharmacokinetics and species-specific reversible isomerization

Pharmaceutical research, 2001-09, Vol.18 (9), p.1336-1344

2001

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Pharmacokinetic mechanisms for obtaining high renal coelimination of phencyclidine and a monoclonal antiphencyclidine antigen-binding fragment of immunoglobulin G in the rat

The Journal of pharmacology and experimental therapeutics, 1998-11, Vol.287 (2), p.616

1998

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SB-242235, a selective inhibitor of p38 mitogenactivated protein kinase. I: Preclinical pharmacokinetics

Xenobiotica, 2002-01, Vol.32 (3), p.221-233

2002

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Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkey

Drug metabolism and disposition, 2004-02, Vol.32 (2), p.172-177

2004

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A single dose of monoclonal anti-phencyclidine IgG offers long-term reductions in phencyclidine behavioral effects in rats

The Journal of pharmacology and experimental therapeutics, 2002-07, Vol.302 (1), p.119-126

2002

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Phencyclidine (PCP) distribution in rats: Unique time profiles of brain and testis accumulation

Clinical pharmacology and therapeutics, 1999-02, Vol.65 (2), p.155-155

1999

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Bardoxolone methyl analog attenuates proteinuria‐induced tubular damage by modulating mitochondrial function

The FASEB journal, 2019-11, Vol.33 (11), p.12253-12263

2019

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Topical application of the synthetic triterpenoid RTA 408 protects mice from radiation-induced dermatitis

Radiation research, 2014-05, Vol.181 (5), p.512

2014

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Quantitative determination of besifloxacin, a novel fluoroquinolone antimicrobial agent, in human tears by liquid chromatography–tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-05, Vol.867 (1), p.105-110

2008

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From anti-fouling to biofilm inhibition: New cytotoxic secondary metabolites from two Indonesian Agelas sponges

Bioorganic & medicinal chemistry, 2010-02, Vol.18 (3), p.1297-1311

2010

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Topical application of the synthetic triterpenoid RTA 408 activates Nrf2 and induces cytoprotective genes in rat skin

Archives of Dermatological Research, 2014-07, Vol.306 (5), p.447-454

2014

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Pullularins E and F, two new peptides from the endophytic fungus Bionectria ochroleuca isolated from the mangrove plant Sonneratia caseolaris

Marine drugs, 2012-05, Vol.10 (5), p.1081-1091

2012

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Prenylation enhances cytotoxicity of apigenin and liquiritigenin in rat H4IIE hepatoma and C6 glioma cells

Food and chemical toxicology, 2007, Vol.45 (1), p.119-124

2007

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The effect of rate of drug administration on the extent and time course of phencyclidine distribution in rat brain, testis, and serum

SB-242235, a selective inhibitor of p38 mitogen-activated protein kinase. I: Preclinical pharmacokinetics

Preclinical pharmacokinetics of SB-203580, a potent inhibitor of p38 mitogen-activated protein kinase

SB-242235, a selective inhibitor of p38 mitogen-activated protein kinase. II: In vitro and in vivo metabolism studies and pharmacokinetic extrapolation to man

Anti-phencyclidine monoclonal antibodies provide long-term reductions in brain phencyclidine concentrations during chronic phencyclidine administration in rats

Effects of lipid A on calcium homeostasis in renal proximal tubules

Development of an in vivo preclinical screen model to estimate absorption and bioavailability of xenobiotics

Nitric oxide generation by renal proximal tubules: role of nitric oxide in the cytotoxicity of lipid A

A52 PRECLINICAL TRIALS IN PULMONARY HYPERTENSION MODELS: NOVEL TARGETS AND DELIVERY: The Bardoxolone Methyl Analog Rta Dh404 Protects Rats From Monocrotaline-Induced Pulmonary Arterial Hypertension

Pharmacokinetics and pharmacodynamics of the novel Nrf2 activator omaveloxolone in primates

Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors

Pharmacodynamics of a monoclonal antiphencyclidine Fab with broad selectivity for phencyclidine-like drugs

SB-239063, a potent and selective inhibitor of p38 map kinase : Preclinical pharmacokinetics and species-specific reversible isomerization

Pharmacokinetic mechanisms for obtaining high renal coelimination of phencyclidine and a monoclonal antiphencyclidine antigen-binding fragment of immunoglobulin G in the rat

SB-242235, a selective inhibitor of p38 mitogenactivated protein kinase. I: Preclinical pharmacokinetics

Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkey

A single dose of monoclonal anti-phencyclidine IgG offers long-term reductions in phencyclidine behavioral effects in rats

Phencyclidine (PCP) distribution in rats: Unique time profiles of brain and testis accumulation

Bardoxolone methyl analog attenuates proteinuria‐induced tubular damage by modulating mitochondrial function

Topical application of the synthetic triterpenoid RTA 408 protects mice from radiation-induced dermatitis

Quantitative determination of besifloxacin, a novel fluoroquinolone antimicrobial agent, in human tears by liquid chromatography–tandem mass spectrometry

From anti-fouling to biofilm inhibition: New cytotoxic secondary metabolites from two Indonesian Agelas sponges

Topical application of the synthetic triterpenoid RTA 408 activates Nrf2 and induces cytoprotective genes in rat skin

Pullularins E and F, two new peptides from the endophytic fungus Bionectria ochroleuca isolated from the mangrove plant Sonneratia caseolaris

Prenylation enhances cytotoxicity of apigenin and liquiritigenin in rat H4IIE hepatoma and C6 glioma cells

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