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Pd-Catalyzed Borylation in Water and Its Application to the Synthesis of Active Pharmaceutical Ingredient (API) Intermediates

Journal of organic chemistry, 2024-09, Vol.89 (17), p.12452-12461

2024

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Recent advances in the synthesis of active pharmaceutical and agrochemical ingredients in micellar media

Current opinion in green and sustainable chemistry, 2023-02, Vol.39, p.100729, Article 100729

2023

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Structure-guided design of antibacterials that allosterically inhibit DNA gyrase

Bioorganic & medicinal chemistry letters, 2019-06, Vol.29 (11), p.1407-1412

2019

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Regioselective synthesis of 1,3,5- and 1,3,4,5-substituted pyrazoles via acylation of N-Boc- N-substituted hydrazones

Tetrahedron, 2011-01, Vol.67 (3), p.612-617

2011

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Reaction of 2-alkyl pyridine N-oxide derivatives with Mosher’s acyl chloride: first example of stereoselective Boekelheide rearrangement

Tetrahedron letters, 2010-12, Vol.51 (50), p.6526-6530

2010

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Highly diastereoselective addition of nitromethane anion to chiral alpha-amidoalkylphenyl sulfones. Synthesis of optically active alpha-amino acid derivatives

Organic & biomolecular chemistry, 2003-12, Vol.1 (23), p.4275-4281

2003

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Discovery of N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a Novel Clinical AMPA Receptor Positive Modulator

Journal of medicinal chemistry, 2010-08, Vol.53 (15), p.5801-5812

2010

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Mechanism insights into an unexpected isomerisation reaction observed during conversion of N-benzyl piperazinones to corresponding N-benzyl thio-piperazinones

Tetrahedron letters, 2011-01, Vol.52 (3), p.448-452

2011

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Synthesis of 5-(3,4-dichlorophenyl)-4-[(methyloxy)methyl]-2-azabicyclo[3.2.1]octane derivatives as constrained aryl-piperidines with activity as triple re-uptake inhibitors

Tetrahedron letters, 2010-10, Vol.51 (42), p.5521-5524

2010

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Reactivity of Chiral α-Amidoalkylphenyl Sulfones with Stabilized Carbanions. Stereoselective Synthesis of Optically Active 1-Aminopyrrolizidine

Journal of organic chemistry, 2004-10, Vol.69 (21), p.7303-7308

2004

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Asymmetric route to spirotetracyclic (1S)-5′,11′-dihydro-3H-spiro[cyclopentane-1,10′-dibenzo[a,d]cyclohepten]-3-one derivatives

Tetrahedron letters, 2011-01, Vol.52 (2), p.329-331

2011

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Synthesis of 5-(3,4-dichlorophenyl)-4-[(methyloxy)methyl]-2-azabicyclo[3.2.1]oc t ane derivatives as constrained aryl-piperidines with activity as triple re-uptake inhibitors

Tetrahedron letters, 2010-10, Vol.51 (42), p.5521-5524

2010

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Reaction of Allylzinc Reagents and Zinc Enolates of Ketones with α-Amidoalkylphenyl Sulfones

Journal of organic chemistry, 2002-06, Vol.67 (13), p.4530-4535

2002

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Synthesis of advanced intermediates for the preparation of aza-analogues of podophyllotoxin

Tetrahedron letters, 2004-03, Vol.45 (10), p.2133-2136

2004

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Regioselective Preparation of N -Methylpyrazole Derivative

Synlett, 2008-09, Vol.2008 (15), p.2283-2286

2008

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Reactivity of chiral exocyclic N-acyliminium ions with aromatic derivatives

Tetrahedron: asymmetry, 2003-05, Vol.14 (9), p.1171-1178

2003

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Reaction of α-Amidoalkylphenyl Sulfones with Lithiated Nitriles: Syn-Selective Synthesis of β-Amino Nitriles

Journal of organic chemistry, 2001-11, Vol.66 (24), p.8264-8267

2001

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Synthesis of Secondary Amines by Reduction of α-Amidoalkylphenyl Sulfones with Sodium Acetoxyborohydride

Synlett, 2003-07, Vol.2003 (8)

2003

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An Efficient Scalable Route for the Synthesis of Enantiomerically Pure tert-Butyl-(1R,4S,6R)-4-(hydroxymethyl)-3-azabicyclo[4.1.0]heptane-3-carboxylate

Organic process research & development, 2010-09, Vol.14 (5), p.1239-1247

2010

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Synthesis of Secondary Aminesby Reduction of α-Amidoalkylphenyl Sulfones with SodiumAcetoxyborohydride

Synlett, 2003 (8), p.1129-1132

2003

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980 nm diode lasers in oral and facial practice: current state of the science and art

International journal of medical sciences, 2009-11, Vol.6 (6), p.358-364

2009

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ChemInform Abstract: Regioselective Synthesis of 1,3,5- and 1,3,4,5-Substituted Pyrazoles via Acylation of N-Boc-N-Substituted Hydrazones

ChemInform, 2011-05, Vol.42 (22), p.no-no

2011

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Reactivity of Chiral α-Amidoalkylphenyl Sulfones with Stabilized Carbanions. Stereoselective Synthesis of Optically Active 1-Aminopyrrolizidine

ChemInform, 2005-02, Vol.36 (8), p.no-no

2005

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Synthesis of Secondary Amines by Reduction of α-Amidoalkylphenyl Sulfones with Sodium Acetoxyborohydride

ChemInform, 2003-10, Vol.34 (41), p.no-no

2003

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Reactivity of Chiral Exocyclic N-Acyliminium Ions with Aromatic Derivatives

ChemInform, 2003-09, Vol.34 (36), p.no-no

2003

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Pd-Catalyzed Borylation in Water and Its Application to the Synthesis of Active Pharmaceutical Ingredient (API) Intermediates

Recent advances in the synthesis of active pharmaceutical and agrochemical ingredients in micellar media

Structure-guided design of antibacterials that allosterically inhibit DNA gyrase

Regioselective synthesis of 1,3,5- and 1,3,4,5-substituted pyrazoles via acylation of N-Boc- N-substituted hydrazones

Reaction of 2-alkyl pyridine N-oxide derivatives with Mosher’s acyl chloride: first example of stereoselective Boekelheide rearrangement

Highly diastereoselective addition of nitromethane anion to chiral alpha-amidoalkylphenyl sulfones. Synthesis of optically active alpha-amino acid derivatives

Discovery of N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a Novel Clinical AMPA Receptor Positive Modulator

Mechanism insights into an unexpected isomerisation reaction observed during conversion of N-benzyl piperazinones to corresponding N-benzyl thio-piperazinones

Synthesis of 5-(3,4-dichlorophenyl)-4-[(methyloxy)methyl]-2-azabicyclo[3.2.1]octane derivatives as constrained aryl-piperidines with activity as triple re-uptake inhibitors

Reactivity of Chiral α-Amidoalkylphenyl Sulfones with Stabilized Carbanions. Stereoselective Synthesis of Optically Active 1-Aminopyrrolizidine

Asymmetric route to spirotetracyclic (1S)-5′,11′-dihydro-3H-spiro[cyclopentane-1,10′-dibenzo[a,d]cyclohepten]-3-one derivatives

Synthesis of 5-(3,4-dichlorophenyl)-4-[(methyloxy)methyl]-2-azabicyclo[3.2.1]oc t ane derivatives as constrained aryl-piperidines with activity as triple re-uptake inhibitors

Reaction of Allylzinc Reagents and Zinc Enolates of Ketones with α-Amidoalkylphenyl Sulfones

Synthesis of advanced intermediates for the preparation of aza-analogues of podophyllotoxin

Regioselective Preparation of N -Methylpyrazole Derivative

Reactivity of chiral exocyclic N-acyliminium ions with aromatic derivatives

Reaction of α-Amidoalkylphenyl Sulfones with Lithiated Nitriles: Syn-Selective Synthesis of β-Amino Nitriles

Synthesis of Secondary Amines by Reduction of α-Amidoalkylphenyl Sulfones with Sodium Acetoxyborohydride

An Efficient Scalable Route for the Synthesis of Enantiomerically Pure tert-Butyl-(1R,4S,6R)-4-(hydroxymethyl)-3-azabicyclo[4.1.0]heptane-3-carboxylate

Synthesis of Secondary Aminesby Reduction of α-Amidoalkylphenyl Sulfones with SodiumAcetoxyborohydride

980 nm diode lasers in oral and facial practice: current state of the science and art

ChemInform Abstract: Regioselective Synthesis of 1,3,5- and 1,3,4,5-Substituted Pyrazoles via Acylation of N-Boc-N-Substituted Hydrazones

Reactivity of Chiral α-Amidoalkylphenyl Sulfones with Stabilized Carbanions. Stereoselective Synthesis of Optically Active 1-Aminopyrrolizidine

Synthesis of Secondary Amines by Reduction of α-Amidoalkylphenyl Sulfones with Sodium Acetoxyborohydride

Reactivity of Chiral Exocyclic N-Acyliminium Ions with Aromatic Derivatives

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