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Selective Plasma Hydrolysis of Glucocorticoid γ-Lactones and Cyclic Carbonates by the Enzyme Paraoxonase: An Ideal Plasma Inactivation Mechanism

Journal of medicinal chemistry, 2000-01, Vol.43 (1), p.19-21

2000

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A convergent strategy towards febrifugine and related compounds

Organic & biomolecular chemistry, 2018, Vol.16 (22), p.4159-4169

2018

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Synthesis and Characterization of Coronanes: Multicyclopropane-Fused Macrocyclic Arrays

Journal of organic chemistry, 2001-04, Vol.66 (7), p.2187-2196

2001

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Thrombin inhibitors based on [5,5] trans-fused indane lactams

Bioorganic & medicinal chemistry letters, 1999-06, Vol.9 (12), p.1657-1662

1999

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A convergent strategy towards febrifugine and related compoundsElectronic supplementary information (ESI) available. CCDC 1450620. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8ob00935j

2018-06

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Tandem Ireland−Claisen Rearrangement Ring-Closing Alkene Metathesis in the Construction of Bicyclic β-Lactam Carboxylic Esters

Journal of organic chemistry, 2000-06, Vol.65 (12), p.3716-3721

2000

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Oxazole Synthesis with Minimal Purification: Synthesis and Application of a ROMPgel Tosmic Reagent

Organic letters, 2001-01, Vol.3 (2), p.271-273

2001

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Solid-Phase Synthesis of Isoxazoles Using Vinyl Ethers as Chameleon Catches

Organic letters, 2001-10, Vol.3 (20), p.3165-3168

2001

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The Squalestatins: Decarboxy and 4-Deoxy Analogues as Potent Squalene Synthase Inhibitors

Journal of medicinal chemistry, 1996-01, Vol.39 (1), p.207-216

1996

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Novel Glucocorticoid Antedrugs Possessing a 17β-(γ-Lactone) Ring

Journal of medicinal chemistry, 2001-02, Vol.44 (4), p.602-612

2001

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The Squalestatins: Inhibitors of Squalene Synthase. Enzyme Inhibitory Activities and in Vivo Evaluation of C3-Modified Analogues

Journal of medicinal chemistry, 1996-03, Vol.39 (7), p.1413-1422

1996

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The Squalestatins: Novel Inhibitors of Squalene Synthase. Enzyme Inhibitory Activities and in vivo Evaluation of C1-Modified Analogs

Journal of medicinal chemistry, 1994-09, Vol.37 (20), p.3274-3281

1994

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The Squalestatins: Synthesis and Biological Activity of Some C3-Modified Analogs; Replacement of a Carboxylic Acid or Methyl Ester with an Isoelectronic Heterocyclic Functionality

Journal of medicinal chemistry, 1995-09, Vol.38 (18), p.3502-3513

1995

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THE SQUALESTATINS, NOVEL INHIBITORS OF SQUALENE SYNTHASE PRODUCED BY A SPECIES OF PHOMA: II. STRUCTURE ELUCIDATION

The Journal of Antibiotics, 1992/05/25, Vol.45(5), pp.648-658

1992

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The squalestatins: tricyclic 3,4-β-lactone and 3,4-oxetane systems

Tetrahedron letters, 2000-09, Vol.41 (39), p.7547-7550

2000

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An Extremely Powerful Acylation Reaction of Alcohols with Acid Anhydrides Catalyzed by Trimethylsilyl Trifluoromethanesulfonate

Journal of organic chemistry, 1998-04, Vol.63 (7), p.2342-2347

1998

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A novel cyclodehydration reaction of hydroxy-phenols using imidate esters as leaving groups

Tetrahedron letters, 1993-11, Vol.34 (46), p.7483-7486

1993

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Ritter-Type Reactions of N-Chlorosaccharin: A Method for the Electrophilic Diamination of Alkenes

Organic letters, 2003-09, Vol.5 (18), p.3313-3315

2003

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Novel glucocorticoid antedrugs possessing a 17beta-(gamma-lactone) ring

Journal of medicinal chemistry, 2001-02, Vol.44 (4), p.602-612

2001

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A recyclable ‘boomerang’ polymer-supported ruthenium catalyst for olefin metathesis

Tetrahedron letters, 1999-12, Vol.40 (49), p.8657-8662

1999

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Inhibitors of cholesterol biosynthesis. 2. 3,5-Dihydroxy-7-(N-pyrrolyl)-6-heptenoates, a novel series of HMG-CoA reductase inhibitors

Journal of medicinal chemistry, 1993-11, Vol.36 (23), p.3658-3662

1993

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Squalene synthase inhibitors : Their potential as hypocholesterolaemic agents

Progress in medicinal chemistry, 1996, Vol.33, p.331-378

1996

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Structurally simplified squalestatins : a convenient route to a 6,7-unsubstituted derivative

Tetrahedron letters, 1993-07, Vol.34 (27)

1993

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The squalestatins: C-3 Decarboxylation studies and rearrangement to the 6,8-dioxabicyclo[3.2.1]octane ring system

Tetrahedron letters, 1993-09, Vol.34 (38), p.6143-6146

1993

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Synthesis of Diverse Macrocyclic Peptidomimetics Utilizing Ring-Closing Metathesis and Solid-Phase Synthesis

Journal of organic chemistry, 2004-02, Vol.69 (4), p.1028-1037

2004

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Selective Plasma Hydrolysis of Glucocorticoid γ-Lactones and Cyclic Carbonates by the Enzyme Paraoxonase: An Ideal Plasma Inactivation Mechanism

A convergent strategy towards febrifugine and related compounds

Synthesis and Characterization of Coronanes: Multicyclopropane-Fused Macrocyclic Arrays

Thrombin inhibitors based on [5,5] trans-fused indane lactams

A convergent strategy towards febrifugine and related compoundsElectronic supplementary information (ESI) available. CCDC 1450620. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8ob00935j

Tandem Ireland−Claisen Rearrangement Ring-Closing Alkene Metathesis in the Construction of Bicyclic β-Lactam Carboxylic Esters

Oxazole Synthesis with Minimal Purification: Synthesis and Application of a ROMPgel Tosmic Reagent

Solid-Phase Synthesis of Isoxazoles Using Vinyl Ethers as Chameleon Catches

The Squalestatins: Decarboxy and 4-Deoxy Analogues as Potent Squalene Synthase Inhibitors

Novel Glucocorticoid Antedrugs Possessing a 17β-(γ-Lactone) Ring

The Squalestatins: Inhibitors of Squalene Synthase. Enzyme Inhibitory Activities and in Vivo Evaluation of C3-Modified Analogues

The Squalestatins: Novel Inhibitors of Squalene Synthase. Enzyme Inhibitory Activities and in vivo Evaluation of C1-Modified Analogs

The Squalestatins: Synthesis and Biological Activity of Some C3-Modified Analogs; Replacement of a Carboxylic Acid or Methyl Ester with an Isoelectronic Heterocyclic Functionality

THE SQUALESTATINS, NOVEL INHIBITORS OF SQUALENE SYNTHASE PRODUCED BY A SPECIES OF PHOMA: II. STRUCTURE ELUCIDATION

The squalestatins: tricyclic 3,4-β-lactone and 3,4-oxetane systems

An Extremely Powerful Acylation Reaction of Alcohols with Acid Anhydrides Catalyzed by Trimethylsilyl Trifluoromethanesulfonate

A novel cyclodehydration reaction of hydroxy-phenols using imidate esters as leaving groups

Ritter-Type Reactions of N-Chlorosaccharin: A Method for the Electrophilic Diamination of Alkenes

Novel glucocorticoid antedrugs possessing a 17beta-(gamma-lactone) ring

A recyclable ‘boomerang’ polymer-supported ruthenium catalyst for olefin metathesis

Inhibitors of cholesterol biosynthesis. 2. 3,5-Dihydroxy-7-(N-pyrrolyl)-6-heptenoates, a novel series of HMG-CoA reductase inhibitors

Squalene synthase inhibitors : Their potential as hypocholesterolaemic agents

Structurally simplified squalestatins : a convenient route to a 6,7-unsubstituted derivative

The squalestatins: C-3 Decarboxylation studies and rearrangement to the 6,8-dioxabicyclo[3.2.1]octane ring system

Synthesis of Diverse Macrocyclic Peptidomimetics Utilizing Ring-Closing Metathesis and Solid-Phase Synthesis

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