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Neoclerodanes as atypical opioid receptor ligands

Journal of medicinal chemistry, 2013-05, Vol.56 (9), p.3435-3443

Prisinzano, Thomas E

2013

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Role of Ventral Subiculum in Context-Induced Relapse to Alcohol Seeking after Punishment-Imposed Abstinence

The Journal of neuroscience, 2016-03, Vol.36 (11), p.3281-3294

2016

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Kappa opioids and the modulation of pain

Psychopharmacology, 2010-06, Vol.210 (2), p.109-119

2010

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The unique psychostimulant profile of (±)‐modafinil: investigation of behavioral and neurochemical effects in mice

The European journal of neuroscience, 2017-01, Vol.45 (1), p.167-174

2017

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Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors

The Journal of biological chemistry, 2013-12, Vol.288 (51), p.36703-36716

2013

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Impact of Pharmacological Manipulation of the κ -Opioid Receptor System on Self-grooming and Anhedonic-like Behaviors in Male Mice

The Journal of pharmacology and experimental therapeutics, 2019-07, Vol.370 (1), p.1

2019

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Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy- N -phenethyl-5-phenylmorphans

Molecules (Basel, Switzerland), 2024-04, Vol.29 (9), p.1926

2024

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Neuropharmacology of the naturally occurring kappa-opioid hallucinogen salvinorin A

Pharmacological reviews, 2011-06, Vol.63 (2), p.316

2011

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Salvinorin A regulates dopamine transporter function via a kappa opioid receptor and ERK1/2-dependent mechanism

Neuropharmacology, 2014-11, Vol.86, p.228-240

2014

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Discovery of Small-Molecule Inhibitors Targeting the E3 Ubiquitin Ligase Activity of the Herpes Simplex Virus 1 ICP0 Protein Using an In Vitro High-Throughput Screening Assay

Journal of virology, 2019-07, Vol.93 (13)

2019

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Natural Products as Tools for Neuroscience: Discovery and Development of Novel Agents to Treat Drug Abuse

Journal of natural products (Washington, D.C.), 2009-03, Vol.72 (3), p.581-587

Prisinzano, Thomas E

2009

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Synthesis and κ‑Opioid Receptor Activity of Furan-Substituted Salvinorin A Analogues

Journal of medicinal chemistry, 2014-12, Vol.57 (24), p.10464-10475

2014

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The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors

Molecules (Basel, Switzerland), 2023-06, Vol.28 (12), p.4848

2023

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Nalfurafine promotes myelination in vitro and facilitates recovery from cuprizone + rapamycin‐induced demyelination in mice

Glia, 2024-06

2024

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Behavioral and Physiological Effects of a Novel Kappa-Opioid Receptor-Based DREADD in Rats

Neuropsychopharmacology (New York, N.Y.), 2016-01, Vol.41 (2), p.402-409

2016

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The kappa-opioid receptor agonist, triazole 1.1, reduces oxycodone self-administration and enhances oxycodone-induced thermal antinociception in male rats

Psychopharmacology, 2021-12, Vol.238 (12), p.3463-3476

2021

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Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil

The Journal of pharmacology and experimental therapeutics, 2009-05, Vol.329 (2), p.738

2009

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Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity

Biochemical pharmacology, 2012-04, Vol.83 (7), p.952-961

2012

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Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans

Molecules (Basel, Switzerland), 2023-06, Vol.28 (12), p.4795

2023

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Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine

The Journal of pharmacology and experimental therapeutics, 2019-11, Vol.371 (2), p.487

2019

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Rapid-Onset Anti-Stress Effects of a Kappa-Opioid Receptor Antagonist, LY2795050, Against Immobility in an Open Space Swim Paradigm in Male and Female Mice

Frontiers in pharmacology, 2021-11, Vol.12, p.775317-775317

2021

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Psychopharmacology of the hallucinogenic sage Salvia divinorum

Life sciences (1973), 2005-12, Vol.78 (5), p.527-531

Prisinzano, Thomas E.

2005

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The G-protein biased kappa opioid agonists, triazole 1.1 and nalfurafine, produce non-uniform behavioral effects in male rhesus monkeys

Pharmacology, biochemistry and behavior, 2022-06, Vol.217, p.173394-173394, Article 173394

2022

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Dose-related effects of salvinorin A in humans: dissociative, hallucinogenic, and memory effects

Psychopharmacology, 2013-03, Vol.226 (2), p.381-392

2013

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Kappa opioid agonists reduce oxycodone self-administration in male rhesus monkeys

Psychopharmacology, 2020-05, Vol.237 (5), p.1471-1480

2020

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Neoclerodanes as atypical opioid receptor ligands

Role of Ventral Subiculum in Context-Induced Relapse to Alcohol Seeking after Punishment-Imposed Abstinence

Kappa opioids and the modulation of pain

The unique psychostimulant profile of (±)‐modafinil: investigation of behavioral and neurochemical effects in mice

Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors

Impact of Pharmacological Manipulation of the κ -Opioid Receptor System on Self-grooming and Anhedonic-like Behaviors in Male Mice

Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy- N -phenethyl-5-phenylmorphans

Neuropharmacology of the naturally occurring kappa-opioid hallucinogen salvinorin A

Salvinorin A regulates dopamine transporter function via a kappa opioid receptor and ERK1/2-dependent mechanism

Discovery of Small-Molecule Inhibitors Targeting the E3 Ubiquitin Ligase Activity of the Herpes Simplex Virus 1 ICP0 Protein Using an In Vitro High-Throughput Screening Assay

Natural Products as Tools for Neuroscience: Discovery and Development of Novel Agents to Treat Drug Abuse

Synthesis and κ‑Opioid Receptor Activity of Furan-Substituted Salvinorin A Analogues

The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors

Nalfurafine promotes myelination in vitro and facilitates recovery from cuprizone + rapamycin‐induced demyelination in mice

Behavioral and Physiological Effects of a Novel Kappa-Opioid Receptor-Based DREADD in Rats

The kappa-opioid receptor agonist, triazole 1.1, reduces oxycodone self-administration and enhances oxycodone-induced thermal antinociception in male rats

Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil

Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity

Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans

Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine

Rapid-Onset Anti-Stress Effects of a Kappa-Opioid Receptor Antagonist, LY2795050, Against Immobility in an Open Space Swim Paradigm in Male and Female Mice

Psychopharmacology of the hallucinogenic sage Salvia divinorum

The G-protein biased kappa opioid agonists, triazole 1.1 and nalfurafine, produce non-uniform behavioral effects in male rhesus monkeys

Dose-related effects of salvinorin A in humans: dissociative, hallucinogenic, and memory effects

Kappa opioid agonists reduce oxycodone self-administration in male rhesus monkeys

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